More articles from Brain
- Mapping p53 Mutations in Low-Grade Glioma: A Voxel-Based Neuroimaging Analysis
Brain tumor location has prognostic implications so these authors explored whether location also correlated with p53 status in 182 patients. Tumors occurring in the left medial temporal and right anterior temporal lobes were associated with high expression of mutant p53 and had significantly worse progression-free survival.
- Percentage Insula Ribbon Infarction of >50% Identifies Patients Likely to Have Poor Clinical Outcome Despite Small DWI Infarct Volume
Using CT or DWI, the authors categorized percentages of insular ribbon infarctions as less or more than 50% and correlated these with clinical outcomes. Only insular ribbon involvement greater than 50% and low NIHSS score at admission correlated with poor outcomes. They concluded that DWI–percentage insula ribbon infarct of >50% independently predicted poor clinical outcome and can help identify patients with stroke likely to have poor outcome despite small admission DWI lesion volumes.
- Early Reperfusion Rates with IV tPA Are Determined by CTA Clot Characteristics
These authors evaluated CTA studies of 228 patients paying special attention to the clot features, and correlated these features with early reperfusion rates. Clot features that predicted successful early reperfusion included: shorter clot, residual flow within the clot, and distal location. Reperfusion was achieved in only 8% of patients with longer and proximal clots and in those without residual flow.