PT  - JOURNAL ARTICLE
AU  - Erbay, Sami H.
AU  - Oljeski, Stephen A.
AU  - Bhadelia, Rafeeque
TI  - Rapid Development of Optic Glioma in a Patient with Hybrid Phakomatosis: Neurofibromatosis Type 1 and Tuberous Sclerosis
DP  - 2004 Jan 01
TA  - American Journal of Neuroradiology
PG  - 36--38
VI  - 25
IP  - 1
4099  - http://www.ajnr.org/content/25/1/36.short
4100  - http://www.ajnr.org/content/25/1/36.full
SO  - Am. J. Neuroradiol.2004 Jan 01; 25
AB  - Summary: Increased propensity for tumor formation in neurofibromatosis and tuberous sclerosis exists because of defective tumor-suppressor genes. Although different tumor-suppressor genes may be involved in neurofibromatosis and tuberous sclerosis, at the cellular level these genes share rather common enzymatic pathways. We believe these genetic malfunctions have resulted in a cumulative or additive effect for rapid growth of optic glioma in the following unusual case that has hybrid phakomatosis.