RT Journal Article
SR Electronic
T1 Central Tegmental Tract Involvement in an Infant with 6-Pyruvoyltetrahydropterin Synthetase Deficiency
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 584
OP 585
VO 27
IS 3
A1 Takanashi, J.
A1 Kanazawa, M.
A1 Kohno, Y.
YR 2006
UL http://www.ajnr.org/content/27/3/584.abstract
AB Summary: We report the case of an asymptomatic 2-month-old infant with 6-pyruvoyltetrahydropterin synthetase deficiency detected through a neonatal phenylketonuria screening program. MR imaging revealed symmetrical lesions in the central tegmental tract with reduced diffusion, which resolved after treatment. A possible explanation for these lesions is intramyelinic edema resulting from brain insults in utero.