RT Journal Article
SR Electronic
T1 Metachronous, Multicentric Giant Cell Tumor of the Sphenoid Bone with Histologic, CT, MR Imaging, and Positron-Emission Tomography/CT Correlation
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 2199
OP 2201
VO 27
IS 10
A1 McKinney, A.M.
A1 Reichert, P.
A1 Short, J.
A1 Dhurairaj, T.
A1 SantaCruz, K.
A1 McKinney, Z.
A1 Kieffer, S.
YR 2006
UL http://www.ajnr.org/content/27/10/2199.abstract
AB SUMMARY: Giant cell tumor (GCT) of the sphenoid bone is a relatively rare entity and metachronous multicentric GCT of the sphenoid is even rarer; we are aware of only 3 previous cases in the literature. We describe here a tumor of the sphenoid bone that was identified 15 years after multiple resections of a GCT of the left inferior pubic ramus. Correlation is made between the histopathologic findings, MR imaging of the brain, CT of the head, and fusion positron-emission tomography (PET)/CT scan performed with fluorine-18 fluoro-2-deoxy-D-glucose (18F-FDG). This report is the first to describe the appearance of a GCT of the sphenoid bone on a fusion PET/CT examination. High metabolic activity in the base of the skull adjacent to the middle cranial fossa was demonstrated in a fashion similar to that of the known pelvic lesion. This case also demonstrates that the increased metabolic activity seen in a GCT of the sphenoid bone may be partially obscured by the adjacent physiologic high metabolic activity of the brain.