RT Journal Article
SR Electronic
T1 MR Spectroscopy in Sinus Mucocele: <em>N</em>-Acetyl Mimics of Brain <em>N</em>-Acetylaspartate
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 2210
OP 2213
VO 27
IS 10
A1 Andre, E.
A1 Xu, M.
A1 Yang, D.
A1 Siow, J.K.
A1 Yeo, T.T.
A1 Xu, Y.
A1 Lim, C.C.T.
YR 2006
UL http://www.ajnr.org/content/27/10/2210.abstract
AB SUMMARY: We describe MR spectroscopy in 2 patients with frontal sinus mucoceles that showed a dominant metabolite peak at 2.0-ppm chemical shift, simulating N-acetylaspartate (NAA) of normal neuronal tissue. In vitro analysis of postsurgical mucocele samples confirmed that the signal at 2.0 ppm was arising from the methyl moiety of an N-acetyl compound. This is probably caused by N-acetylgalactosamine or N-acetylglucosamine, which are glycoproteins found in normal respiratory mucus produced by the paranasal sinus epithelium.