PT  - JOURNAL ARTICLE
AU  - Gupta, V.
AU  - Tanvir, R.
AU  - Garg, A.
AU  - Gaikwad, S.B.
AU  - Mishra, N.K.
TI  - Heparin-Induced Thrombocytopenia in a Case of Endovascular Aneurysm Coiling
DP  - 2007 Jan 01
TA  - American Journal of Neuroradiology
PG  - 155--158
VI  - 28
IP  - 1
4099  - http://www.ajnr.org/content/28/1/155.short
4100  - http://www.ajnr.org/content/28/1/155.full
SO  - Am. J. Neuroradiol.2007 Jan 01; 28
AB  - SUMMARY: We report a case of 46-year-old man who underwent endovascular coil embolization for left anterior inferior cerebellar and posterior inferior cerebellar aneurysms. During embolization of both aneurysms, thrombotic complications were observed along with a relative lack of response to heparin. Intra-arterial abciximab was used to recanalize an almost completely occluded posterior inferior cerebellar artery. A marked decrease in platelet counts was found soon after embolization, which normalized within a few days. Serologic tests confirmed heparin-induced thrombocytopenia. This syndrome should be considered in cases with thromboembolic complications during endovascular procedures, particularly in patients undergoing repeated heparin exposure. A sudden decrease in platelet counts and lack of response to heparin, manifested as a relative lack of increasing activated clotting time, should make one suspect this syndrome.