RT Journal Article
SR Electronic
T1 Heparin-Induced Thrombocytopenia in a Case of Endovascular Aneurysm Coiling
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 155
OP 158
VO 28
IS 1
A1 Gupta, V.
A1 Tanvir, R.
A1 Garg, A.
A1 Gaikwad, S.B.
A1 Mishra, N.K.
YR 2007
UL http://www.ajnr.org/content/28/1/155.abstract
AB SUMMARY: We report a case of 46-year-old man who underwent endovascular coil embolization for left anterior inferior cerebellar and posterior inferior cerebellar aneurysms. During embolization of both aneurysms, thrombotic complications were observed along with a relative lack of response to heparin. Intra-arterial abciximab was used to recanalize an almost completely occluded posterior inferior cerebellar artery. A marked decrease in platelet counts was found soon after embolization, which normalized within a few days. Serologic tests confirmed heparin-induced thrombocytopenia. This syndrome should be considered in cases with thromboembolic complications during endovascular procedures, particularly in patients undergoing repeated heparin exposure. A sudden decrease in platelet counts and lack of response to heparin, manifested as a relative lack of increasing activated clotting time, should make one suspect this syndrome.