RT Journal Article
SR Electronic
T1 C-Arm CT Measurement of Cerebral Blood Volume: An Experimental Study in Canines
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 917
OP 922
DO 10.3174/ajnr.A1513
VO 30
IS 5
A1 Ahmed, A.S.
A1 Zellerhoff, M.
A1 Strother, C.M.
A1 Pulfer, K.A.
A1 Redel, T.
A1 Deuerling-Zheng, Y.
A1 Royalty, K.
A1 Consigny, D.
A1 Niemann, D.B.
YR 2009
UL http://www.ajnr.org/content/30/5/917.abstract
AB BACKGROUND AND PURPOSE: Cerebral blood volume (CBV) is an important parameter in estimating the viability of brain tissue following an ischemic event. We tested the hypothesis that C-arm CT measurements of CBV would correlate well with those made with perfusion CT (PCT).MATERIALS AND METHODS: CBV was measured in 12 canines by using PCT and C-arm CT. Two measurements with each technique were made on each animal; a different injection protocol was used for each of these techniques. PCT was performed by using a 64-section V-scanner. C-arm CT was performed by using a biplane Artis dBA system. PCT images were transferred to a commercially available workstation for postprocessing and analysis; C-arm CT images were transferred to a commercially available workstation for postprocessing and analysis by using prototype software. From each animal, 2 sections from each technique were selected for analysis.RESULTS: There was good agreement of both the color maps and absolute numbers between the 2 techniques. The maximum and mean deviations of values between the 2 techniques for the first 5 animals were 30.20% and 7.82%; for the second 7 animals, these values were 26.79% and 7.40%. The maximum and mean deviations between the 2 C-arm CT studies performed on the first 5 animals were 33.15% and 12.24%; for the second 7 animals, these values were 41.15% and 10.89%.CONCLUSIONS: In these healthy animals, measurement of CBV with C-arm CT compared well with measurements made with PCT.