RT Journal Article SR Electronic T1 Hypothalamus Syndrome in Opticospinal Multiple Sclerosis JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP E153 OP E155 DO 10.3174/ajnr.A2278 VO 32 IS 8 A1 Zhang, Y. A1 Dong, R. A1 Fan, H. A1 Li, S. A1 Geng, D. YR 2011 UL http://www.ajnr.org/content/32/8/E153.abstract AB SUMMARY: This study describes a case of a patient with OSMS who presented with somnolence, periodic fever, memory impairment, and amenorrhea. Serum prolactin levels were found to be higher than normal. MR imaging showed a bilateral involvement of the hypothalamus. The clinical presentation, laboratory examination, and MR imaging findings suggested a diagnosis of hypothalamus syndrome in this patient. AQP4aquaporin-4CMSconventional MSCNScentral nervous systemEAEexperimental autoimmune encephalomyelitisFLAIRfluid-attenuated inversion recoveryIgGimmunoglobulin GIL-6Interleukin-6LESCLlongitudinally extensive spinal cord lesionMSmultiple sclerosisNMOneuromyelitis opticaOSMSopticospinal MS