RT Journal Article
SR Electronic
T1 Trastuzumab (Herceptin)
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1373
OP 1374
DO 10.3174/ajnr.A2619
VO 32
IS 8
A1 Gemmete, J.J.
A1 Mukherji, S.K.
YR 2011
UL http://www.ajnr.org/content/32/8/1373.abstract
AB SUMMARY: Herceptin (trastuzumab) is a human monoclonal antibody that interferes with the HER2 receptor. It is currently the only FDA-approved therapeutic antibody for HER2-positive breast cancer. This article will present the mechanism at action as well as the clinical role at this monoclonal antibody. FDAUS Food and Drug AdministrationHER, HER2, HER3, and HER4human epidermal growth factor receptors