PT  - JOURNAL ARTICLE
AU  - Blustajn, J.
AU  - Krystal, S.
AU  - Taussig, D.
AU  - Ferrand-Sorbets, S.
AU  - Dorfmüller, G.
AU  - Fohlen, M.
TI  - Optimizing the Detection of Subtle Insular Lesions on MRI When Insular Epilepsy Is Suspected
AID  - 10.3174/ajnr.A6143
DP  - 2019 Sep 01
TA  - American Journal of Neuroradiology
PG  - 1581--1585
VI  - 40
IP  - 9
4099  - http://www.ajnr.org/content/40/9/1581.short
4100  - http://www.ajnr.org/content/40/9/1581.full
SO  - Am. J. Neuroradiol.2019 Sep 01; 40
AB  - SUMMARY: Insular epilepsy is underdiagnosed and accounts for a number of failed operations. Identifying insular target lesions on MR imaging can help guide intracranial electroencephalography and improve the outcome of surgery. In this study, we present a novel method of exploring the insular region for subtle lesions on 3D MR imaging by MPR postprocessing of slices in oblique reference planes. Using this method, we retrospectively reviewed presurgical MRIs that were initially considered to have normal findings in 7 pediatric patients with intractable insular epilepsy. Insular epilepsy was confirmed in these patients on stereo-electroencephalography and histopathology. The MPR postprocessing method we describe helped detect subtle insular lesions in all 7 patients.FCDfocal cortical dysplasiaSEEGstereo-electroencephalography