RT Journal Article
SR Electronic
T1 Diagnostic Accuracy and Failure Mode Analysis of a Deep Learning Algorithm for the Detection of Cervical Spine Fractures
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1550
OP 1556
DO 10.3174/ajnr.A7179
VO 42
IS 8
A1 Voter, A.F.
A1 Larson, M.E.
A1 Garrett, J.W.
A1 Yu, J.-P.J.
YR 2021
UL http://www.ajnr.org/content/42/8/1550.abstract
AB BACKGROUND AND PURPOSE: Artificial intelligence decision support systems are a rapidly growing class of tools to help manage ever-increasing imaging volumes. The aim of this study was to evaluate the performance of an artificial intelligence decision support system, Aidoc, for the detection of cervical spinal fractures on noncontrast cervical spine CT scans and to conduct a failure mode analysis to identify areas of poor performance.MATERIALS AND METHODS: This retrospective study included 1904 emergent noncontrast cervical spine CT scans of adult patients (60 [SD, 22] years, 50.3% men). The presence of cervical spinal fracture was determined by Aidoc and an attending neuroradiologist; discrepancies were independently adjudicated. Algorithm performance was assessed by calculation of the diagnostic accuracy, and a failure mode analysis was performed.RESULTS: Aidoc and the neuroradiologist's interpretation were concordant in 91.5% of cases. Aidoc correctly identified 67 of 122 fractures (54.9%) with 106 false-positive flagged studies. Diagnostic performance was calculated as the following: sensitivity, 54.9% (95% CI, 45.7%–63.9%); specificity, 94.1% (95% CI, 92.9%–95.1%); positive predictive value, 38.7% (95% CI, 33.1%–44.7%); and negative predictive value, 96.8% (95% CI, 96.2%–97.4%). Worsened performance was observed in the detection of chronic fractures; differences in diagnostic performance were not altered by study indication or patient characteristics.CONCLUSIONS: We observed poor diagnostic accuracy of an artificial intelligence decision support system for the detection of cervical spine fractures. Many similar algorithms have also received little or no external validation, and this study raises concerns about their generalizability, utility, and rapid pace of deployment. Further rigorous evaluations are needed to understand the weaknesses of these tools before widespread implementation.AIartificial intelligenceASiRadaptive statistical iterative reconstructionDSSdecision support systemCSFxcervical spinal fractures