Multiple linear regression analysis of the absolute change of CBF during acetazolamide administration as the dependent variable
| Variable | Coefficient | Standard Error | t | P value |
|---|---|---|---|---|
| Model 1: | ||||
| CBV (mL/100g) | −7.9 | 2.5 | −3.0 | <.005 |
| Model 2: | ||||
| CBV (mL/100g) | −15.6 | 2.5 | −6.1 | <.0001 |
| CMRO2 (mL/100g/min) | 14.0 | 2.9 | 4.8 | <.0001 |
Note.—CBV signifies cerebral blood volume; CMRO2, cerebral metabolic rate of oxygen.