Table 2:

The 96 genes that had a statistically significant (P < .05) differential expression between the aneurysm and the control artery

Rank	Gene	+/−
1	Fast skeletal muscle troponin C mRNA	−
2	Haptoglobin mRNA	+
3	Endothelial differentiation gene 1 protein	+
4	Muscle α-actinin subunit, N′-terminal region	−
5	Matrix metalloproteinase 9	+
6	Caveolin	−
7	Alcohol dehydrogenase, class I	+
8	Endothelin-1	−
9	Myosin light chain 2
10	Osteoglycin	−
11	Type VIII collagen α -1 chain	−
12	Osteopontin	+
13	Neutrophil attractant/activation protein-1 (NAP-1)	−
14	Interleukin 1 receptor antagonist	+
15	Apolipoprotein E	+
16	IL-8 receptor	−
17	Cytochrome P4B1 isoform	−
18	Monocyte chemoattractant protein-1 (MCP-1)	+
19	Tissue inhibitor of metalloproteinase-4 (TIMP-4)	+
20	Myosin heavy chain (MHC)	−
21	Transforming growth factor-β 2	−
22	Heme oxygenase 1 (HO1)	+
23	Al adenosine receptor	+
24	Osteonectin	+
25	p53 protein	−
26	Peroxisome proliferator activated receptor (PPAR) gamma 3	+
27	Cathepsin L	+
28	Apolipoprotein B	−
29	Elongation factor 1 β	+
30	Calmodulin-dependent protein kinase II-delta dash	−
31	Secreted frizzled-related protein 2	+
32	Glutathione S-transferase	−
33	Vascular cell adhesion molecule (VCAM-1)	+
34	Endothelin converting enzyme (ECE1)	−
35	Platelet-derived growth factor-β	+
36	Matrix metalloproteinase-12	+
37	Decorin=proteoglycan	−
38	Galectin-3	+
39	Glycoprotein IIb (GPIIb)	+
40	Metallo-elastase, macrophage	+
41	Fertilin α subunit	−
42	Growth response 1 zinc-finger transcription factor	−
43	α2 type I collagen	−
44	α3 type IV collagen	+
45	Apolipoprotein D	+
46	Endothelin B receptor	−
47	Insulin-like growth factor 1 precursor (IGF-1)	+
48	Neuregulin 1 α isoform	−
49	Protein phosphatase-1 catalytic subunit (EC 3.1.3.-)	+
50	Heme oxygenase-2	−
51	Class II alcohol dehydrogenase, isozyme 1	+
52	Functional messenger ribonucleoprotein particle major protein p50	−
53	factor XI	−
54	Rho-associated-Ser/Thr kinase	+
55	Acyl CoA binding protein	−
56	Protein kinase Cβ (PKC-β)	+
57	Bone morphogenetic protein 2 (BMP-2)	−
58	Heat shock protein 47	+
59	Retinoic acid receptor RXR α mRNA	+
60	α 1 type X collagen	+
61	Coagulation factor VII	−
62	Interleukin-2	−
63	Elongation factor 1 delta (Rabef1D)	+
64	fas antigen spliced variant	−
65	glucose transporter type 4 (GLUT4)	−
66	Cellular disintegrin ADAM 6e (ADAM 6e)	−
67	Atrial natriuretic polypeptides	+
68	Matrix metalloproteinase-2	+
69	Major histocompatibility complex class II RLA-DR-α gene	+
70	Tissue inhibitor of metalloproteinase-2 (TIMP2)	+
71	Adenosine A3 receptor mRNA	−
72	Bone morphogenetic protein 7	−
73	Forkhead transcription factor L2 (FoxL2) gene	−
74	Neuronal nitric oxide synthase NOS1	+
75	Tissue-type plasminogen activator mRNA	+
76	Endothelin receptor type A	−
77	Phosphorylase kinase α subunit mRNA	−
78	α-1-antitrypsin	+
79	Thrombomodulin precursor (Thbd)	−
80	Neutrophil-activating peptide 78 (ENA-78)	−
81	Calcineurin A β	−
82	α-1 type V collagen (COL5A1)	−
83	Interferon γ	−
84	NADPH-cytochrome P450 reductase	−
85	Fibroblast growth factor	−
86	Thrombospondin 2-like protein (THBS2)	+
87	Tryptophan hydroxylase	−
88	Hyperoxia induced (H1) 1 gene encoding a TIMP	+
89	Inducible nitric oxide synthase (NOS2)	−
90	Glycoprotein IIIa (GPIIIa)	+
91	Elongation factor 1 γ	+
92	CD86	−
93	Calmodulin-dependent protein kinase II-γ dash2	−
94	Protein inhibitor of neuronal nitric oxide synthase	+
95	Vascular endothelial growth factor receptor 3	+
96	Ksp-cadherin	−

Note:—The genes are ranked according to the degree of significance of the differential expression. + indicates that the gene was overexpressed in the aneurysm; −, the gene was underexpressed in the aneurysm.