Summary of dependent variables in 10 consecutive patients who underwent basilar artery stenting for symptomatic athero-occlusive disease
Variables |
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Patient-related variables |
Age >70 years |
Sex |
Pre-existing history of diabetes |
Pre-existing history of significant heart disease |
Indication for stenting |
Rate of onset of index event (abrupt vs progressive) |
Recent failed balloon angioplasty |
Preoperative acute/subacute infarction |
Technique-related variables |
Experience (procedure performed 1999–2000 versus 2001–2003) |
Primary stenting (versus pre-dilation of target lesion with angioplasty balloon) |
More than one stent implanted |
Type of anesthesia (general versus conscious sedation) |
Major branch artery jailed by stent construct |
Residual stenosis <20% |
Perioperative antithrombotic therapy |
Preloaded with clopidogrel before procedure |
Intraoperative anticoagulation with documented activated clotting times ≥250 seconds |
Intraoperative IIb/IIIa inhibitors |
Postoperative IIb/IIIa inhibitors ≥12 hours |
Postoperative anticoagulation with heparin and/or warfarin for ≥48 hours |
Postoperative maintenance therapy with dual antiplatelet agents |
Anatomic characteristics |
Lesion location |
Lesion extension across basilar artery branch ostia |
Number of patent vertebral arteries contributing to basilar circulation |
At least moderate stenosis affecting 2 or more major basilar artery branches |
At least 1 posterior communicating artery giving collateral flow to the basilar artery |
Lesion characteristics |
Mori classification |
Pretreatment stenosis ≥80% |
Lesion ulceration |
Prestent lesion lumen ≤0.5 mm |
Lesion length >10 mm |
Lesion angle >45° |