Table 2:

Regions of gray and white matter volume loss in patients with ALS compared with HCs

Cluster Size^{^a}	BA	Regions	MNI Coordinates (mm)			TValues
Cluster Size^{^a}	BA	Regions	X	Y	Z	TValues
Gray matter volume loss
54	BA 39	R angular gyrus	33	−57	45	4.28
29	BA 4	L precentral gyrus	−45	−6	30	4.02
65	BA 46	L middle frontal gyrus	−24	40	19	4.00
46	BA 4	R precentral gyrus	30	−16	41	3.72
	BA 4	R precentral gyrus	38	−10	43	3.43
22	BA 48	R rolandic operculum	56	2	14	3.62
White matter volume loss
51		L superior frontal lobe	−19	53	28	4.14
240		R supplementary motor area	8	−26	54	3.92
		R precentral region	17	−15	70	3.61
		R precentral region	16	−20	59	3.57
47		L supplementary motor area	−3	−21	56	3.80
25		L inferior temporal area	−40	−28	−13	3.59

a The number of voxels. P< .001 uncorrected within at least 20 contiguous voxels.