Table 2:

Mean fcMRI values for MS and healthy control groups, by sex

Region	MNI Coordinates	Mean fcMRI Value (SD)						P Value^a
Region	MNI Coordinates	Female Control Subjects	Female Patients	Male Control Subjects	Male Patients	All Control Subjects	All Patients	P Value^a
Left medial frontal gyrus	[−7 61 3.8]	0.432 (0.773)	1.768 (1.833)	−0.044 (0.899)	1.050 (0.857)	0.194 (0.860)	1.409 (1.454)	.0001
Right medial frontal gyrus	[7 59 7.4]	1.292 (1.057)	2.317 (1.352)	1.101 (1.543)	2.367 (1.076)	1.197 (1.305)	2.342 (1.202)	.0005
Left anterior cingulate	[−7 40 −11.8]	−0.094 (0.471)	0.510 (1.017)	−0.430 (0.509	0.603 (1.145)	−0.262 (0.512)	0.556 (1.066)	.0002
Right putamen	[27 10 −15.4]	−0.550 (0.913)	0.436 (0.681)	−0.339 (0.735)	0.237 (0.689)	−0.445 (0.823)	0.336 (0.681)	.0001
Left middle temporal gyrus	[−56 −4 −23.8]	0.376 (0.404)	0.991 (1.010)	0.162 (0.332)	1.253 (1.142)	0.269 (0.380)	1.122 (1.068)	.0001
Left DLPFC	[−25 40 19.4]	−0.986 (0.660)	−0.147 (0.809)	−0.194 (0.637)	0.848 (0.830)	−0.590 (0.754)	−0.497 (0.881)	NS
Right caudate	[19 24 3.8]	−0.642 (0.909)	0.210 (0.651)	0.094 (0.818)	−0.463 (0.612)	−0.274 (0.929)	−0.127 (0.710)	NS