The Study of Cerebral Hemodynamics in the Hyperacute Stage of Fat Embolism Induced by Triolein Emulsion

American Journal of Neuroradiology

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Fig 1.
Sequential T2-weighted (A), Gd-enhanced T1-weighted (B), diffusion-weighted (C), and ADC map (D) images at 30 minutes (first column), 2 hours (second column), 4 hours (third column), and 6 hours (fourth column) after triolein emulsion infusion in cat 320. T2 hyperintensity (A) is shown at 30 minutes, extends into the subcortical white matter at 2 hours, is maximal in size and intensity at 4 hours, and decreases thereafter. Lesion enhancement on Gd-enhanced T1-weighted imaging (B) is revealed from 30 minutes, increases at 2 hours, and decreases thereafter. Diffusion-weighted images (C) show mild hyperintensity at 2, 4, and 6 hours. ADC map images (D) all reveal isointensity over time.

Table 3:

Signal intensity ratios of lesion to contralateral normal side on DWI and ADC map images

Time	n	Mean ± SD	Range
DWI
30 min	14	1.08 ± 0.09	0.95–1.23
2 h	14	1.15 ± 0.09	1.01–1.34
4 h	14	1.12 ± 0.18	0.77–1.40
6 h	14	1.11 ± 0.14	0.94–1.35
ADC
30 min	14	1.01 ± 0.12	0.86–1.29
2 h	14	1.17 ± 0.17	0.93–1.46
4 h	14	1.11 ± 0.19	0.84–1.36
6 h	14	1.05 ± 0.24	0.74–1.53

Table 4:

Relative ratios of lesion to contralateral normal side on perfusion-weighted images

Time	n	Mean ± SD	Range
rCBV
30 min	14	1.03 ± 0.20	0.72–1.35
2 h	14	0.96 ± 0.23	0.67–1.23
4 h	14	0.98 ± 0.09	0.82–1.14
6 h	14	1.00 ± 0.15	0.84–1.30
rCBF
30 min	14	1.12 ± 0.39	0.53–1.82
2 h	14	1.07 ± 0.36	0.25–1.38
4 h	14	1.14 ± 0.34	0.64–1.75
6 h	14	0.94 ± 094	0.53–1.15
MTT
30 min	14	0.98 ± 0.07	0.89–1.08
2 h	14	0.97 ± 0.15	0.70–1.21
4 h	14	0.95 ± 0.09	0.80–1.08
6 h	14	0.99 ± 0.10	0.87–1.17