OtherRESEARCH PERSPECTIVES
Interventional Neuroradiology: The Role of Experimental Models in Scientific Progress
J. Raymond, I. Salazkin, G. Gevry and T.N. Nguyen
American Journal of Neuroradiology March 2007, 28 (3) 401-405;
J. Raymond
I. Salazkin
G. Gevry

References
- ↵Box GEP. Robustness in the strategy of scientific model building. In: Launer RL, Wilkinson GN, eds. Robustness in Statistics. New York: Academic Press;1979 :201–36
- ↵Raymond J, Guilbert F, Weill A, et al. Safety, science, and sales: a request for valid clinical trials to assess new devices for endovascular treatment of intracranial aneurysms. AJNR Am J Neuroradiol 2004;25:1128–30
- ↵Raymond J, Guilbert F, Weill A, et al. Unruptured intracranial aneurysms: a call for randomized clinical trials. AJNR Am J Neuroradiol 2006;27:242–43
- ↵Raymond J, Leblanc P, Chagnon M, et al. New devices designed to improve the long-term results of endovascular treatment of intracranial aneurysms. A proposition for a randomized clinical trial to assess their safety and efficacy. Interventional Neuroradiology 2004;10:93–102
- ↵Lieber BB, Stancampiano AP, Wakhloo AK. Alteration of hemodynamics in aneurysm models by stenting: influence of stent porosity. Ann Biomed Eng 1997;25:460–69
- ↵Ohta MHM, Wetzel S, Lylyk P, et al. Impact of stent design on intraaneurysmal flow: a computer simulation study. Intervenional Neuroradiology 2004;10:85–94
- ↵Ding YH, Dai D, Lewis DA, et al Angiographic and histologic analysis of experimental aneurysms embolized with platinum coils, Matrix, and HydroCoil. AJNR Am J Neuroradiol 2005;26:1757–63
- Murayama Y, Tateshima S, Gonzalez NR, et al. Matrix and bioabsorbable polymeric coils accelerate healing of intracranial aneurysms: long-term experimental study. Stroke 2003;34:2031–37
- ↵Raymond J, Leblanc P, Desfaits AC, et al. In situ beta radiation to prevent recanalization after coil embolization of cerebral aneurysms. Stroke 2002;33:421–27
- ↵Piotin M, Iijima A, Wada H, et al. Increasing the packing of small aneurysms with complex-shaped coils: an in vitro study. AJNR Am J Neuroradiol 2003;24:1446–48
- ↵Brisman JL, Song JK, Niimi Y, et al. Treatment options for wide-necked intracranial aneurysms using a self-expandable hydrophilic coil and a self-expandable stent combination. AJNR Am J Neuroradiol 2005;26:1237–40
- ↵Yoshino Y, Niimi Y, Song JK, et al. Endovascular treatment of intracranial aneurysms: comparative evaluation in a terminal bifurcation aneurysm model in dogs. J Neurosurg 2004;101:996–1003
- ↵Desfaits AC, Raymond J, Muizelaar JP. Growth factors stimulate neointimal cells in vitro and increase the thickness of the neointima formed at the neck of porcine aneurysms treated by embolization. Stroke 2000;31:498–507
- ↵Raymond J, Metcalfe A, Desfaits AC, et al. Alginate for endovascular treatment of aneurysms and local growth factor delivery. AJNR Am J Neuroradiol 2003;24:1214–21
- ↵Niimi Y, Song J, Madrid M, et al. Endosaccular treatment of intracranial aneurysms using matrix coils: early experience and midterm follow-up. Stroke 2006;37:1028–32
- ↵Gillies D. Introductory survey of the interpretations. In: Philosophical Theories of Probability. London, UK: Routledge;2000 :10
- ↵Raymond J, Mounayer C, Salazkin I, et al. Safety and effectiveness of radioactive coil embolization of aneurysms: effects of radiation on recanalization, clot organization, neointima formation, and surrounding nerves in experimental models. Stroke 2006;37:2147–52
- ↵Degrazie D. On the question of personhood beyond Homo Sapiens. In: Peter Singer, ed. In Defense of Animals: The Second Wave. 2nd ed. Malden, Mass: Blackwell Publishing;2005 :40–53
- ↵Canadian Council on Animal Care Website. Available at: http://www.ccac.ca. Accessed on July 22,2006
- ↵Ryder R. Speciesism in the laboratory. In: Peter Singer, ed. In Defense of Animals: The Second Wave. 2nd ed. Malden, Mass: Blackwell Publishing;2005 :87–103
In this issue
Advertisement
J. Raymond, I. Salazkin, G. Gevry, T.N. Nguyen
Interventional Neuroradiology: The Role of Experimental Models in Scientific Progress
American Journal of Neuroradiology Mar 2007, 28 (3) 401-405;
0 Responses
Jump to section
- Article
- Abstract
- The Fundamental Role of Research in Interventional Neuroradiology
- The Use of Experimental Models
- The Necessity for Animal Models
- The “Unrealistic” Nature of Animal Models
- The Moral Discomforts Associated with the Use of Healthy Animals in Research
- Consideration and Respect for Experimental Animals
- The Convergence of Moral, Scientific, and Pragmatic Aspects of a Research Program
- Acknowledgments
- Footnotes
- References
- Figures & Data
- Info & Metrics
- Responses
- References
Related Articles
- No related articles found.
Cited By...
- Current status of training environments in neuro-interventional practice: are animal models still contemporary?
- Dual-Lumen Balloon Catheters May Improve Liquid Embolization of Vascular Malformations: An Experimental Study in Swine
- Testing Flow Diverters in Giant Fusiform Aneurysms: A New Experimental Model Can Show Leaks Responsible for Failures
- Reply:
- A New Canine Carotid Artery Bifurcation Aneurysm Model for the Evaluation of Neurovascular Devices
- In Vivo Experimental Intracranial Aneurysm Models: A Systematic Review
- Endovascular Coiling of Cerebral Aneurysms Using "Bioactive" or Coated-Coil Technologies: A Systematic Review of the Literature
This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.
More in this TOC Section
Similar Articles
Advertisement