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Idiopathic Hypertrophic Spinal Pachymeningitis: Report of Two Cases with Typical MR Imaging Findings

S. Pai, C.T. Welsh, S. Patel and Z. Rumboldt
American Journal of Neuroradiology March 2007, 28 (3) 590-592;
S. Pai
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C.T. Welsh
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S. Patel
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Z. Rumboldt
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    Fig 1.

    A, Sagittal fast spin-echo (FSE) T2-weighted image of the cervical and upper thoracic spine shows a mass of very low signal intensity (arrows) within the spinal canal located adjacent to the posterior aspect of the T1 through T6 vertebral bodies. High signal intensity is present centrally within the spinal cord, indicative of cord edema. There is also thickening and hypointensity of the dura posterior to the spinal cord (arrowheads).

    B, Axial FSE T2-weighted image at T5 level shows a hypointense mass (arrow) in the anterior aspect of the spinal canal that appears to be arising from the dura. The lesion is displacing the spinal cord posteriorly and completely effacing the intradural subarachnoid spaces.

    C, Axial postcontrast T1-weighted image at a level similar to that of B reveals thick enhancement of the anterior epidural mass with central nonenhancing area (arrowheads).

    D, Photomicrograph shows fibrosis with plump reactive fibroblasts. Chronic inflammatory infiltrate is consisting chiefly of plasma cells (arrows) with additional lymphocytes (arrowheads) and scattered histiocytes (macrophages) (hematoxylin and eosin, original magnification 40×).

  • Fig 2.
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    Fig 2.

    A, Sagittal fast spin-echo (FSE) T2-weighted image shows a hypointense mass (arrowheads) in the anterior aspect of the spinal canal that extends from C3 to T1 level.

    B, Corresponding sagittal postcontrast T1-weighted image with fat suppression reveals attenuated enhancement of the mass, which is predominantly peripheral with central nonenhancing portions (arrowheads).

Tables

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  • Characteristics of reported cases of idiopathic hypertrophic spinal pachymeningitis (IHSP) that included MR imaging findings

    StudyPatient Age (years) and SexSpinal Levels InvolvedLesion Length in SegmentsLocation in Spinal CanalRelationship to DuraMRI Signal IntensityMRI Enhancement Pattern
    Ashkenazi et al865/FT1–T55DorsalDuralNAHomogenous*
    Botella et al1055/FCranial–C22Dorsal & ventralDural↓T2 ≈T1Peripheral
    Claus et al1831/FT3–L111CircumferentialIntradural↓T2 ≈T1Homogenous
    Digman et al1570/FAll25CircumferentialDuralNAPeripheral*
    Dumont et al1430/FC4–T37DorsalDural↓T2 ≈T1Peripheral
    Friedman and Flanders1324/FCranial–C77CircumferentialDural↓T2 ↓T1Peripheral
    Friedman and Flanders1351/MAll25DorsalDural↓T2 ↓T1Peripheral
    Friedman and Flanders1365/FCranial–C22CircumferentialDural↓T2 ↓T1Peripheral
    Kanamori et al1128/MT5–L29CircumferentialDuralNAPeripheral
    Mikawa et al958/FC7–T1112Dorsal & ventralDural↓T1Peripheral
    Park et al1656/FC6–T810Dorsal & ventralDural↓T2 ≈T1Peripheral
    Pai et al**47/FT1–T66Dorsal & ventralIntra- and extradural↓T2 ↓T1Peripheral
    Pai et al**68/FC3–T38Dorsal & ventralIntradural↓T2 ≈T1Peripheral
    Sridhar et al1248/FC7–T1112CircumferentialDural↓T2 ↓T1NA
    Voller et al1754/MCranial-C77DorsalDuralNAPeripheral
    • Note:—The imaging features were assessed based on inspection of the provided images or on the description of findings, in cases when the respective images were not included in the reports. ↓ indicates hypointense; ≈ , isointense; *, poor image quality; **, this study; NA, not applicable (not performed or not mentioned).

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American Journal of Neuroradiology: 28 (3)
American Journal of Neuroradiology
Vol. 28, Issue 3
March 2007
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S. Pai, C.T. Welsh, S. Patel, Z. Rumboldt
Idiopathic Hypertrophic Spinal Pachymeningitis: Report of Two Cases with Typical MR Imaging Findings
American Journal of Neuroradiology Mar 2007, 28 (3) 590-592;

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Idiopathic Hypertrophic Spinal Pachymeningitis: Report of Two Cases with Typical MR Imaging Findings
S. Pai, C.T. Welsh, S. Patel, Z. Rumboldt
American Journal of Neuroradiology Mar 2007, 28 (3) 590-592;
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