Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Other Publications
    • ajnr

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

Welcome to the new AJNR, Updated Hall of Fame, and more. Read the full announcements.


AJNR is seeking candidates for the position of Associate Section Editor, AJNR Case Collection. Read the full announcement.

 

  • Getting new auth cookie, if you see this message a lot, tell someone!
  • Getting new auth cookie, if you see this message a lot, tell someone!
Research ArticleINTERVENTIONAL

mRNA Expression in Rabbit Experimental Aneurysms: A Study Using Gene Chip Microarrays

W.I. Mangrum, F. Farassati, R. Kadirvel, C.P. Kolbert, S. Raghavakaimal, D. Dai, Y.H. Ding, D. Grill, V.G. Khurana and D.F. Kallmes
American Journal of Neuroradiology May 2007, 28 (5) 864-869;
W.I. Mangrum
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
F. Farassati
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
R. Kadirvel
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
C.P. Kolbert
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
S. Raghavakaimal
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
D. Dai
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Y.H. Ding
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
D. Grill
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
V.G. Khurana
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
D.F. Kallmes
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. ↵
    Khurana VG, Smith LA, Baker TA, et al. Protective vasomotor effects of in vivo recombinant endothelial nitric oxide synthase gene expression in a canine model of cerebral vasospasm. Stroke 2002;33:782–89
    Abstract/FREE Full Text
  2. ↵
    Khurana VG, Sohni YR, Mangrum WI, et al. Section on cerebrovascular surgery: Galbraith Award: Endothelial nitric oxide synthase (eNOS) and heme oxygenase-1 (HO-1) gene polymorphisms predict susceptibility to aneurysmal subarachnoid hemorrhage (SAH) and post-SAH cerebral vasospasm. Clin Neurosurg 2004;51:343–50
    PubMed
  3. ↵
    Ribourtout E, Raymond J. Gene therapy and endovascular treatment of intracranial aneurysms. Stroke 2004;35:786–93
    Abstract/FREE Full Text
  4. Abrahams JM, Forman MS, Grady MS, et al. Delivery of human vascular endothelial growth factor with platinum coils enhances wall thickening and coil impregnation in a rat aneurysm model. AJNR Am J Neuroradiol 2001;22:1410–17
    Abstract/FREE Full Text
  5. ↵
    Peters DG, Kassam A, St Jean PL, et al. Functional polymorphism in the matrix metalloproteinase-9 promoter as a potential risk factor for intracranial aneurysm. Stroke 1999;30:2612–16
    Abstract/FREE Full Text
  6. ↵
    Stehbens WE. The ultrastructure of experimental aneurysms in rabbits. Pathology 1985;17:87–95
    PubMedWeb of Science
  7. Stehbens WE. In re: histological and morphologic comparison of experimental aneurysms with human intracranial aneurysms. AJNR Am J Neuroradiol 2000;21:1769–73
    FREE Full Text
  8. ↵
    Abruzzo T, Shengelaia GG, Dawson RC 3rd, et al. Histologic and morphologic comparison of experimental aneurysms with human intracranial aneurysms. AJNR Am J Neuroradiol 1998;19:1309–14
    Abstract
  9. ↵
    Altes TA, Cloft HJ, Short JG, et al. 1999 ARRS Executive Council Award. Creation of saccular aneurysms in the rabbit: a model suitable for testing endovascular devices. American Roentgen Ray Society. AJR Am J Roentgenol 2000;174:349–54
    CrossRefPubMedWeb of Science
  10. ↵
    Peters DG, Kassam AB, Feingold E, et al. Molecular anatomy of an intracranial aneurysm: coordinated expression of genes involved in wound healing and tissue remodeling. Stroke 2001;32:1036–42
    Abstract/FREE Full Text
  11. ↵
    Krex D, Schackert HK, Schackert G. Genesis of cerebral aneurysms—an update. Acta Neurochirurgica 2001;143:429–48; discussion 448–49
    CrossRefPubMed
  12. ↵
    Takagi Y, Ishikawa M, Nozaki K, et al. Increased expression of phosphorylated c-Jun amino-terminal kinase and phosphorylated c-Jun in human cerebral aneurysms: role of the c-Jun amino-terminal kinase/c-Jun pathway in apoptosis of vascular walls. Neurosurgery 2002;51:997–1002; discussion 1002–04
    CrossRefPubMedWeb of Science
  13. ↵
    Fukuda, S., et al. Prevention of rat cerebral aneurysm formation by inhibition of nitric oxide synthase. Circulation 2000;101:2532–38
    Abstract/FREE Full Text
  14. Ohkuma, H., et al. Role of a decreased expression of the local renin-angiotensin system in the etiology of cerebral aneurysms. Circulation 2003;108:785–87
    Abstract/FREE Full Text
  15. ↵
    Zhang B, Fugleholm K, Day LB, et al. Molecular pathogenesis of subarachnoid haemorrhage. Int J Biochem Cell Biol 2003;35:1341–60
    CrossRefPubMedWeb of Science
  16. ↵
    Bruno G, Todor R, Lewis I, et al. Vascular extracellular matrix remodeling in cerebral aneurysms. J Neurosurg 1998;89:431–40
    PubMedWeb of Science
  17. St Jean P, Hart B, Webster M, et al. Alpha-1-antitrypsin deficiency in aneurysmal disease. Hum Hered 1996;46:92–97
    CrossRefPubMedWeb of Science
  18. ↵
    Todor DR, Lewis I, Bruno G, et al. Identification of a serum gelatinase associated with the occurrence of cerebral aneurysms as pro-matrix metalloproteinase-2. Stroke 1998;29:1580–83
    Abstract/FREE Full Text
  19. ↵
    Kim SC, Singh M, Huang J, et al. Matrix metalloproteinase-9 in cerebral aneurysms. Neurosurgery 1997;41:642–66; discussion 646–47
    CrossRefPubMedWeb of Science
  20. ↵
    Zhao J, Han L, Wang S. In situ localization of mRNA gelatinases in cerebral aneurysms. Chung-Hua i Hsueh Tsa Chih 1999;79:822–24
  21. ↵
    Mimata C, Kitaoka M, Nagahiro S, et al. Differential distribution and expressions of collagens in the cerebral aneurysmal wall. Acta Neuropathologica 1997;94:197–206
    CrossRefPubMed
  22. Ostergaard JR, Reske-Nielsen E, Buhl J. Deficiency of reticular fibers in cerebral arteries. On the etiology of saccular aneurysms in childhood. Br J Neurosurg 1989;3:113–15
    CrossRefPubMed
  23. Neil-Dwyer G, Bartlett JR, Nicholls AC, et al. Collagen deficiency and ruptured cerebral aneurysms. A clinical and biochemical study. J Neurosurg 1983;59:16–20
    PubMedWeb of Science
  24. Pope FM, Nicholls AC, Narcisi P, et al. Some patients with cerebral aneurysms are deficient in type III collagen. Lancet 1981;1:973–75
    PubMedWeb of Science
  25. ↵
    Majamaa K, Savolainen ER, Myllyla VV. Synthesis of structurally unstable type III procollagen in patients with cerebral artery aneurysm. Biochim Biophys Acta 1992;1138:191–96
    PubMed
  26. ↵
    Brooks AR, Lelkes PI, Rubanyi GM. Gene expression profiling of human aortic endothelial cells exposed to disturbed flow and steady laminar flow. Physiol Genomics 2002;9:27–41
    Abstract/FREE Full Text
  27. Absi TS, Sundt TM 3rd, Tung WS, et al. Altered patterns of gene expression distinguishing ascending aortic aneurysms from abdominal aortic aneurysms: complementary DNA expression profiling in the molecular characterization of aortic disease. J Thoracic Cardiovasc Surg 2003;126:344–57; discussion 357
    CrossRefPubMedWeb of Science
  28. Armstrong PJ, Johanning JM, Calton WC Jr, et al. Differential gene expression in human abdominal aorta: aneurysmal versus occlusive disease. J Vasc Surg 2002;35:346–55
    CrossRefPubMedWeb of Science
  29. ↵
    Tung WS, Lee JK, Thompson RW. Simultaneous analysis of 1176 gene products in normal human aorta and abdominal aortic aneurysms using a membrane-based complementary DNA expression array. J Vasc Surg 2001;34:143–50
    CrossRefPubMedWeb of Science
  30. ↵
    Yajima N, Masuda M, Miyazaki M, et al. Oxidative stress is involved in the development of experimental abdominal aortic aneurysm: a study of the transcription profile with complementary DNA microarray. J Vasc Surg 2002;36:379–85
    CrossRefPubMedWeb of Science
  31. Dunn LT, Stewart E, Murray GD, et al. The influence of apolipoprotein E genotype on outcome after spontaneous subarachnoid hemorrhage: a preliminary study. Neurosurgery 1006;48:1006–10
  32. Khurana VG, Sohni YR, Mangrum WI, et al. Endothelial nitric oxide synthase T-786C single nucleotide polymorphism: a putative genetic marker differentiating small versus large ruptured intracranial aneurysms. Stroke 2003;34:2555–59
    Abstract/FREE Full Text
  33. ↵
    Suzuki Y, et al. Nitric oxide metabolites in the cisternal cerebral spinal fluid of patients with subarachnoid hemorrhage. Neurosurgery 1997;41:807–11; discussion 811–12
    CrossRefPubMed
  34. ↵
    Hara A, Yoshimi N, Mori H. Evidence for apoptosis in human intracranial aneurysms. Neurol Res 1998;20:127–30
    PubMedWeb of Science
  35. ↵
    Kondo S, Hashimoto N, Kikuchi H, et al. Apoptosis of medial smooth muscle cells in the development of saccular cerebral aneurysms in rats. Stroke 1998;29:181–88; discussion 189
    Abstract/FREE Full Text
  36. ↵
    Sakaki T, Kohmura E, Kishiguchi T, et al. Loss and apoptosis of smooth muscle cells in intracranial aneurysms. Studies with in situ DNA end labeling and antibody against single-stranded DNA. Acta Neurochir (Wien) 1997;139:469–74; discussion 474–75
    CrossRefPubMed
  37. ↵
    Stehbens WE. Apoptosis and matrix vesicles in the genesis of arterial aneurysms of cerebral arteries. Stroke 1998;29:1478–80
    FREE Full Text
  38. ↵
    Austin G, Fisher S, Dickson D, et al. The significance of the extracellular matrix in intracranial aneurysms. Ann Clin Lab Sci 1993;23:97–105
    Abstract/FREE Full Text
  39. ↵
    Gaetani P, Rodriguez y Baena R, Tartara F, et al. Metalloproteases and intracranial vascular lesions. Neurol Res 1999;21:385–90
    CrossRefPubMed
  40. ↵
    Eckel JE, Gennings C, Therneau TM, et al. Normalization of two-channel microarray experiments: a semiparametric approach. Bioinformatics 2005;21:1078–83
    Abstract/FREE Full Text
  41. ↵
    Lockhart DJ, Dong H, Byrne MC, et al. Expression monitoring by hybridization to high-density oligonucleotide arrays. Nat Biotechnol 1996;14:1675–80
    CrossRefPubMedWeb of Science
  42. ↵
    Sadamasa N, Nozaki K, Hashimoto N. Disruption of gene for inducible nitric oxide synthase reduces progression of cerebral aneurysms. Stroke 2003;34:2980–84
    Abstract/FREE Full Text
  43. Coutard M. Experimental cerebral aneurysms in the female heterozygous Blotchy mouse. Int J Exp Pathol 1999;80:357–67
    CrossRefPubMed
  44. Torres VE, Cai Y, Chen X, et al. Vascular expression of polycystin-2. J Am Soc Nephrol 2001;12:1–9
    Abstract/FREE Full Text
  45. ↵
    Arnaout MA. The vasculopathy of autosomal dominant polycystic kidney disease: insights from animal models. Kidney Int 2000;58:2599–610
    CrossRefPubMed
  46. ↵
    Lee DW, Yuki I, Murayama Y, et al. A histologic and molecular analysis of thrombus organization and healing in the swine experimental aneurysm model. Presentation at the American Society of Neuroradiology, San Diego, Calif; May 4,2006 .
  47. ↵
    Sakomura Y, Nagashima H, Aoka Y, et al, Expression of peroxisome proliferator-activated receptor-gamma in vascular smooth muscle cells is upregulated in cystic medial degeneration of annuloaortic ectasia in Marfan syndrome. Circulation 2002;106(12 Suppl 1):24
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 28 (5)
American Journal of Neuroradiology
Vol. 28, Issue 5
May 2007
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
mRNA Expression in Rabbit Experimental Aneurysms: A Study Using Gene Chip Microarrays
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
W.I. Mangrum, F. Farassati, R. Kadirvel, C.P. Kolbert, S. Raghavakaimal, D. Dai, Y.H. Ding, D. Grill, V.G. Khurana, D.F. Kallmes
mRNA Expression in Rabbit Experimental Aneurysms: A Study Using Gene Chip Microarrays
American Journal of Neuroradiology May 2007, 28 (5) 864-869;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
mRNA Expression in Rabbit Experimental Aneurysms: A Study Using Gene Chip Microarrays
W.I. Mangrum, F. Farassati, R. Kadirvel, C.P. Kolbert, S. Raghavakaimal, D. Dai, Y.H. Ding, D. Grill, V.G. Khurana, D.F. Kallmes
American Journal of Neuroradiology May 2007, 28 (5) 864-869;
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Rabbit aneurysm models mimic histologic wall types identified in human intracranial aneurysms
  • Differential Gene Expression in Coiled versus Flow-Diverter-Treated Aneurysms: RNA Sequencing Analysis in a Rabbit Aneurysm Model
  • Gene expression comparison of flow diversion and coiling in an experimental aneurysm model
  • RNA-Sequencing Analysis of Messenger RNA/MicroRNA in a Rabbit Aneurysm Model Identifies Pathways and Genes of Interest
  • Healing of saccular aneurysms following platinum coil embolization: lack of improved efficacy with vitamin C supplementation
  • MicroRNA-29 in Aortic Dilation: Implications for Aneurysm Formation
  • Genomics of Human Intracranial Aneurysm Wall
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • SAVE vs. Solumbra Techniques for Thrombectomy
  • Contrast-Induced Encephalopathy after NeuroIR
  • CT Perfusion&Reperfusion in Acute Ischemic Stroke
Show more Interventional

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editors Choice
  • Fellow Journal Club
  • Letters to the Editor

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

Special Collections

  • Special Collections

Resources

  • News and Updates
  • Turn around Times
  • Submit a Manuscript
  • Author Policies
  • Manuscript Submission Guidelines
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Submit a Case
  • Become a Reviewer/Academy of Reviewers
  • Get Peer Review Credit from Publons

Multimedia

  • AJNR Podcast
  • AJNR SCANtastic
  • Video Articles

About Us

  • About AJNR
  • Editorial Board
  • Not an AJNR Subscriber? Join Now
  • Alerts
  • Feedback
  • Advertise with us
  • Librarian Resources
  • Permissions
  • Terms and Conditions

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire