Research ArticleINTERVENTIONAL
mRNA Expression in Rabbit Experimental Aneurysms: A Study Using Gene Chip Microarrays
W.I. Mangrum, F. Farassati, R. Kadirvel, C.P. Kolbert, S. Raghavakaimal, D. Dai, Y.H. Ding, D. Grill, V.G. Khurana and D.F. Kallmes
American Journal of Neuroradiology May 2007, 28 (5) 864-869;
W.I. Mangrum
F. Farassati
R. Kadirvel
C.P. Kolbert
S. Raghavakaimal
D. Dai
Y.H. Ding
D. Grill
V.G. Khurana

References
- ↵Khurana VG, Smith LA, Baker TA, et al. Protective vasomotor effects of in vivo recombinant endothelial nitric oxide synthase gene expression in a canine model of cerebral vasospasm. Stroke 2002;33:782–89
- ↵Khurana VG, Sohni YR, Mangrum WI, et al. Section on cerebrovascular surgery: Galbraith Award: Endothelial nitric oxide synthase (eNOS) and heme oxygenase-1 (HO-1) gene polymorphisms predict susceptibility to aneurysmal subarachnoid hemorrhage (SAH) and post-SAH cerebral vasospasm. Clin Neurosurg 2004;51:343–50
- ↵Ribourtout E, Raymond J. Gene therapy and endovascular treatment of intracranial aneurysms. Stroke 2004;35:786–93
- Abrahams JM, Forman MS, Grady MS, et al. Delivery of human vascular endothelial growth factor with platinum coils enhances wall thickening and coil impregnation in a rat aneurysm model. AJNR Am J Neuroradiol 2001;22:1410–17
- ↵Peters DG, Kassam A, St Jean PL, et al. Functional polymorphism in the matrix metalloproteinase-9 promoter as a potential risk factor for intracranial aneurysm. Stroke 1999;30:2612–16
- ↵Stehbens WE. The ultrastructure of experimental aneurysms in rabbits. Pathology 1985;17:87–95
- Stehbens WE. In re: histological and morphologic comparison of experimental aneurysms with human intracranial aneurysms. AJNR Am J Neuroradiol 2000;21:1769–73
- ↵Abruzzo T, Shengelaia GG, Dawson RC 3rd, et al. Histologic and morphologic comparison of experimental aneurysms with human intracranial aneurysms. AJNR Am J Neuroradiol 1998;19:1309–14
- ↵Altes TA, Cloft HJ, Short JG, et al. 1999 ARRS Executive Council Award. Creation of saccular aneurysms in the rabbit: a model suitable for testing endovascular devices. American Roentgen Ray Society. AJR Am J Roentgenol 2000;174:349–54
- ↵Peters DG, Kassam AB, Feingold E, et al. Molecular anatomy of an intracranial aneurysm: coordinated expression of genes involved in wound healing and tissue remodeling. Stroke 2001;32:1036–42
- ↵
- ↵Takagi Y, Ishikawa M, Nozaki K, et al. Increased expression of phosphorylated c-Jun amino-terminal kinase and phosphorylated c-Jun in human cerebral aneurysms: role of the c-Jun amino-terminal kinase/c-Jun pathway in apoptosis of vascular walls. Neurosurgery 2002;51:997–1002; discussion 1002–04
- ↵Fukuda, S., et al. Prevention of rat cerebral aneurysm formation by inhibition of nitric oxide synthase. Circulation 2000;101:2532–38
- Ohkuma, H., et al. Role of a decreased expression of the local renin-angiotensin system in the etiology of cerebral aneurysms. Circulation 2003;108:785–87
- ↵Zhang B, Fugleholm K, Day LB, et al. Molecular pathogenesis of subarachnoid haemorrhage. Int J Biochem Cell Biol 2003;35:1341–60
- ↵Bruno G, Todor R, Lewis I, et al. Vascular extracellular matrix remodeling in cerebral aneurysms. J Neurosurg 1998;89:431–40
- St Jean P, Hart B, Webster M, et al. Alpha-1-antitrypsin deficiency in aneurysmal disease. Hum Hered 1996;46:92–97
- ↵Todor DR, Lewis I, Bruno G, et al. Identification of a serum gelatinase associated with the occurrence of cerebral aneurysms as pro-matrix metalloproteinase-2. Stroke 1998;29:1580–83
- ↵Kim SC, Singh M, Huang J, et al. Matrix metalloproteinase-9 in cerebral aneurysms. Neurosurgery 1997;41:642–66; discussion 646–47
- ↵Zhao J, Han L, Wang S. In situ localization of mRNA gelatinases in cerebral aneurysms. Chung-Hua i Hsueh Tsa Chih 1999;79:822–24
- ↵
- Neil-Dwyer G, Bartlett JR, Nicholls AC, et al. Collagen deficiency and ruptured cerebral aneurysms. A clinical and biochemical study. J Neurosurg 1983;59:16–20
- Pope FM, Nicholls AC, Narcisi P, et al. Some patients with cerebral aneurysms are deficient in type III collagen. Lancet 1981;1:973–75
- ↵Majamaa K, Savolainen ER, Myllyla VV. Synthesis of structurally unstable type III procollagen in patients with cerebral artery aneurysm. Biochim Biophys Acta 1992;1138:191–96
- ↵Brooks AR, Lelkes PI, Rubanyi GM. Gene expression profiling of human aortic endothelial cells exposed to disturbed flow and steady laminar flow. Physiol Genomics 2002;9:27–41
- Absi TS, Sundt TM 3rd, Tung WS, et al. Altered patterns of gene expression distinguishing ascending aortic aneurysms from abdominal aortic aneurysms: complementary DNA expression profiling in the molecular characterization of aortic disease. J Thoracic Cardiovasc Surg 2003;126:344–57; discussion 357
- Armstrong PJ, Johanning JM, Calton WC Jr, et al. Differential gene expression in human abdominal aorta: aneurysmal versus occlusive disease. J Vasc Surg 2002;35:346–55
- ↵Tung WS, Lee JK, Thompson RW. Simultaneous analysis of 1176 gene products in normal human aorta and abdominal aortic aneurysms using a membrane-based complementary DNA expression array. J Vasc Surg 2001;34:143–50
- ↵Yajima N, Masuda M, Miyazaki M, et al. Oxidative stress is involved in the development of experimental abdominal aortic aneurysm: a study of the transcription profile with complementary DNA microarray. J Vasc Surg 2002;36:379–85
- Dunn LT, Stewart E, Murray GD, et al. The influence of apolipoprotein E genotype on outcome after spontaneous subarachnoid hemorrhage: a preliminary study. Neurosurgery 1006;48:1006–10
- Khurana VG, Sohni YR, Mangrum WI, et al. Endothelial nitric oxide synthase T-786C single nucleotide polymorphism: a putative genetic marker differentiating small versus large ruptured intracranial aneurysms. Stroke 2003;34:2555–59
- ↵
- ↵Hara A, Yoshimi N, Mori H. Evidence for apoptosis in human intracranial aneurysms. Neurol Res 1998;20:127–30
- ↵Kondo S, Hashimoto N, Kikuchi H, et al. Apoptosis of medial smooth muscle cells in the development of saccular cerebral aneurysms in rats. Stroke 1998;29:181–88; discussion 189
- ↵
- ↵Stehbens WE. Apoptosis and matrix vesicles in the genesis of arterial aneurysms of cerebral arteries. Stroke 1998;29:1478–80
- ↵Austin G, Fisher S, Dickson D, et al. The significance of the extracellular matrix in intracranial aneurysms. Ann Clin Lab Sci 1993;23:97–105
- ↵
- ↵Eckel JE, Gennings C, Therneau TM, et al. Normalization of two-channel microarray experiments: a semiparametric approach. Bioinformatics 2005;21:1078–83
- ↵Lockhart DJ, Dong H, Byrne MC, et al. Expression monitoring by hybridization to high-density oligonucleotide arrays. Nat Biotechnol 1996;14:1675–80
- ↵Sadamasa N, Nozaki K, Hashimoto N. Disruption of gene for inducible nitric oxide synthase reduces progression of cerebral aneurysms. Stroke 2003;34:2980–84
- Torres VE, Cai Y, Chen X, et al. Vascular expression of polycystin-2. J Am Soc Nephrol 2001;12:1–9
- ↵
- ↵Lee DW, Yuki I, Murayama Y, et al. A histologic and molecular analysis of thrombus organization and healing in the swine experimental aneurysm model. Presentation at the American Society of Neuroradiology, San Diego, Calif; May 4,2006 .
- ↵Sakomura Y, Nagashima H, Aoka Y, et al, Expression of peroxisome proliferator-activated receptor-gamma in vascular smooth muscle cells is upregulated in cystic medial degeneration of annuloaortic ectasia in Marfan syndrome. Circulation 2002;106(12 Suppl 1):24
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W.I. Mangrum, F. Farassati, R. Kadirvel, C.P. Kolbert, S. Raghavakaimal, D. Dai, Y.H. Ding, D. Grill, V.G. Khurana, D.F. Kallmes
mRNA Expression in Rabbit Experimental Aneurysms: A Study Using Gene Chip Microarrays
American Journal of Neuroradiology May 2007, 28 (5) 864-869;
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