Article Figures & Data
Figures
- Fig 1.
The pie chart shows the distribution of 52 eyes in 26 patients into different clinical stages.
- Fig 2.
Oblique coronal localizer sequence demonstrates the orientation of acquired images for both the PD and GM sequences, perpendicular to the long axis of the temporal lobe or medial hippocampus.
- Fig 3.
PD (left) and GM (right) images obtained in the identical oblique coronal plane demonstrate LGN height measurements in a 43-year-old healthy male volunteer. Specifically, LGN height is determined by drawing a line from the apex of the convexity perpendicular to the base of the LGN. The left image is from the PD sequence, and the right one, from GM sequence.
- Fig 4.
A 36-year-old man with bilateral stage 4 open-angle glaucoma demonstrates bilateral LGN atrophy as shown on both PD (left) and GM (right) sequences.
- Fig 5.
GM images demonstrate visualization of the LGN on 2 different oblique coronal sections in a healthy volunteer and show outlining of the LGN as performed for volume analysis.
- Fig 6.
Temporal horns are measured on the GM sequence as a control brain region used to correct all the measurements of LGN size obtained from the PD and GM sequences.
- Fig 7.
Clearer demarcation of gray and white matter is demonstrated in the GM sequence image (right), compared with the PD sequence image (left). Higher signal intensity of the Virchow-Robin space (small white arrows) and the CSF (large white arrows) adjacent to the LGN is notable on the GM sequences.
Tables
- Table 1:
Comparison of LGN size in patients with glaucoma and volunteers as assessed by various parametersa,b
PDhR PDhL PDvR PDvL GMhR GMhL GMvR GMvL Patients 4.36 ± 0.61 4.31 ± 0.61 98.0 ± 27.2 93.7 ± 25.8 4.20 ± 0.71 4.00 ± 0.85 85.2 ± 27.1 80.5 ± 23.6 Controls 5.05 ± 0.41 4.99 ± 0.41 143.5 ± 22.3 143.1 ± 19.7 4.88 ± 0.51 4.77 ± 0.47 131.7 ± 18.5 129.6 ± 21.0 -
a Covariates appearing in the model are evaluated at the following value: temporal horn width (cumulative) = 4.3885.
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b All P values < 10−3.
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Stage PDhR PDhL Sum PDvR PDvL Sum GMhR GMhL Sum GMvR GMvL Sum L −.353a,b −.428 −.405 −.468 −.525 −.523 −.400 −.512 −.473 −.499 −.478 −.512 .077b,c .029 .040 .016 .006 .006 .043 .008 .015 .010 .014 .008 R −.374b −.514 −.461 −.460 −.401 −.455 −.330b −.395 −.375b −.350b −.386b −.379b .060c .007 .018 .018 .042 .020 .099c .046 .059c .080c .093c .057c A −.455 −.589 −.541 −.581 −.582 −.613 −.458 −.570 −.533 −.547 −.520 −.560 .019 .002 .004 .002 .002 .001 .019 .002 .005 .004 .006 .003 -
a r value.
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b Parameters without significant difference (P> .05).
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c P value.
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