Embolization of Intracranial Aneurysms with HydroSoft Coils: Results of the Korean Multicenter Study

Article Figures & Data

Download figure
Open in new tab
Download powerpoint
Fig 1.
Pre- and postexpansion state of the HydroSoft coil. This platinum coil consists of an inner core of hydrogel and a stretch-resistant filament. It expands and fills up to 40% more volume than a bare platinum coil.
Download figure
Open in new tab
Download powerpoint
Fig 2.
Improved degree of occlusion. A, A 70-year-old woman with elective coiling of a posterior communicating artery aneurysm. Postembolization angiogram shows residual filling into the aneurysm sac (arrow). B, A 7-month follow-up angiogram shows complete obliteration of the aneurysm lumen (arrow).
Download figure
Open in new tab
Download powerpoint
Fig 3.
Improved degree of occlusion. A, A 40-year-old man with a ruptured anterior communicating artery aneurysm. Immediate postembolization angiogram demonstrates residual filling into the aneurysmal sac. B, An 8-month follow-up angiogram shows complete occlusion of aneurysmal sac.
Download figure
Open in new tab
Download powerpoint
Fig 4.
Worsened degree of occlusion. A, A 60-year-old woman with a paraclinoid aneurysm. Immediate postembolization angiogram shows complete occlusion of the aneurysm. B, A 1-year follow-up angiogram reveals minor recanalization at the neck.

Table 1:

Demographics of patients treated with HydroSoft coils

Table 3:

Degree of aneurysmal occlusion at immediately postprocedure and at the last follow-up

Table 4:

Cases showing recanalization in HydroSoft coil group

Patient No./Sex/ Age (yr)	Type of Recanalization	H-H	Location	Size (mm)	PD (%)	%HS	Interval (mo)
8/M/47	Minor	1	SCA	6.1 × 5.3 × 4.9	24	64	8
21/M/46	Major	4	ACA	3.8 × 2.4 × 2.3	73	100	6
75/F/63	Major	2	Basilar	7.0 × 7.5 × 8.5	30	51	10

H-H indicates Hunt and Hess grade; PD, packing density; % HS, % length of HydroSoft coils among total coils deployed; Interval, interval from coil embolization to diagnosis of aneurysm recanalization; SCA, superior cerebellar artery; ACA, anterior cerebral artery.

Table 5:

Results of regression analysis for variables related to aneurysm recanalization

Variable	P Value
Variable	Simple Logistic Regression Analysis	Multiple Logistic Regression Analysis
% length of HydroSoft coils	0.581	0.622
Presentation, ruptured versus unruptured	0.001^*	0.002^*
Maximal aneurysm diameter	0.890	0.440
Aneurysm volume	0.081	0.062
Aneurysm location, anterior versus posterior circulation	0.440	0.542
Degree of occlusion, incomplete versus complete or near complete	0.061	0.155
Packing attenuation	0.417	0.103

Table 6:

Bare platinum or coated coil experiences with follow-up results in the literature

Series (ref. no.)	Coating Material	No. of Aneurysms	Major Recanalization	Mean Follow-Up Interval	Study Design
Sluzewski et al.²⁰	None	145	28%	6 months	Retrospective, single-center
Kagn et al.²	PGLA	39	13%	6 months	Retrospective, single-center
Niimi et al.²¹	PGLA	47	21%	12 months	Retrospective, single-center
Gunnarsson et al.²²	Hydrogel	121	22%	16 months	Retrospective, single-center
Current study	Hydrogel	127	2%	11 months	Prospective, multicenter