Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Other Publications
    • ajnr

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

Welcome to the new AJNR, Updated Hall of Fame, and more. Read the full announcements.


AJNR is seeking candidates for the position of Associate Section Editor, AJNR Case Collection. Read the full announcement.

 

Research ArticleBrain

Persistent Diffusion-Restricted Lesions in Bevacizumab-Treated Malignant Gliomas Are Associated with Improved Survival Compared with Matched Controls

S. Mong, B.M. Ellingson, P.L. Nghiemphu, H.J. Kim, L. Mirsadraei, A. Lai, W. Yong, T.M. Zaw, T.F. Cloughesy and W.B. Pope
American Journal of Neuroradiology October 2012, 33 (9) 1763-1770; DOI: https://doi.org/10.3174/ajnr.A3053
S. Mong
aFrom the Departments of Radiological Sciences (S.M., B.M.E., W.B.P., H.J.K., T.M.Z.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
B.M. Ellingson
aFrom the Departments of Radiological Sciences (S.M., B.M.E., W.B.P., H.J.K., T.M.Z.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
P.L. Nghiemphu
bNeurology (T.F.C., A.L., P.L.N.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
H.J. Kim
aFrom the Departments of Radiological Sciences (S.M., B.M.E., W.B.P., H.J.K., T.M.Z.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
L. Mirsadraei
cPathology (W.Y., L.M.), David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
A. Lai
bNeurology (T.F.C., A.L., P.L.N.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
W. Yong
cPathology (W.Y., L.M.), David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
T.M. Zaw
aFrom the Departments of Radiological Sciences (S.M., B.M.E., W.B.P., H.J.K., T.M.Z.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
T.F. Cloughesy
bNeurology (T.F.C., A.L., P.L.N.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
W.B. Pope
aFrom the Departments of Radiological Sciences (S.M., B.M.E., W.B.P., H.J.K., T.M.Z.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

Article Information

vol. 33 no. 9 1763-1770
DOI 
https://doi.org/10.3174/ajnr.A3053
PubMed 
22538078

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received November 21, 2011
  • Accepted after revision January 17, 2012
  • Published online October 8, 2012.

Copyright & Usage 
© 2012 by American Journal of Neuroradiology

Author Information

  1. S. Monga,
  2. B.M. Ellingsona,
  3. P.L. Nghiemphub,
  4. H.J. Kima,
  5. L. Mirsadraeic,
  6. A. Laib,
  7. W. Yongc,
  8. T.M. Zawa,
  9. T.F. Cloughesyb and
  10. W.B. Popea
  1. aFrom the Departments of Radiological Sciences (S.M., B.M.E., W.B.P., H.J.K., T.M.Z.)
  2. bNeurology (T.F.C., A.L., P.L.N.)
  3. cPathology (W.Y., L.M.), David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California
  1. Please address correspondence to Whitney B. Pope, UCLA Radiological Sciences, Box 951721, BL-428 CHS, Los Angeles, CA 90095-1721; e-mail: wpope{at}mednet.ucla.edu
View Full Text

Altmetrics

Cited By...

  • 87 Citations
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Diffusion-Weighted Imaging in Cancer: Physical Foundations and Applications of Restriction Spectrum Imaging
    Nathan S. White, Carrie R. McDonald, Niky Farid, Josh Kuperman, David Karow, Natalie M. Schenker-Ahmed, Hauke Bartsch, Rebecca Rakow-Penner, Dominic Holland, Ahmed Shabaik, Atle Bjørnerud, Tuva Hope, Jona Hattangadi-Gluth, Michael Liss, J. Kellogg Parsons, Clark C. Chen, Steve Raman, Daniel Margolis, Robert E. Reiter, Leonard Marks, Santosh Kesari, Arno J. Mundt, Christopher J. Kane, Bob S. Carter, William G. Bradley, Anders M. Dale
    Cancer Research 2014 74 17
  • Metastatic Disease of the Nervous System
    Whitney B. Pope
    2018 149
  • Lessons From Anti–Vascular Endothelial Growth Factor and Anti–Vascular Endothelial Growth Factor Receptor Trials in Patients With Glioblastoma
    Christine Lu-Emerson, Dan G. Duda, Kyrre E. Emblem, Jennie W. Taylor, Elizabeth R. Gerstner, Jay S. Loeffler, Tracy T. Batchelor, Rakesh K. Jain
    Journal of Clinical Oncology 2015 33 10
  • Response Assessment in Neuro-Oncology Criteria for Gliomas: Practical Approach Using Conventional and Advanced Techniques
    D.J. Leao, P.G. Craig, L.F. Godoy, C.C. Leite, B. Policeni
    American Journal of Neuroradiology 2020 41 1
  • Advanced imaging techniques for neuro-oncologic tumor diagnosis, with an emphasis on PET-MRI imaging of malignant brain tumors
    Wynton B. Overcast, Korbin M. Davis, Chang Y. Ho, Gary D. Hutchins, Mark A. Green, Brian D. Graner, Michael C. Veronesi
    Current Oncology Reports 2021 23 3
  • Bevacizumab for malignant gliomas: current indications, mechanisms of action and resistance, and markers of response
    Ryota Tamura, Toshihide Tanaka, Keisuke Miyake, Kazunari Yoshida, Hikaru Sasaki
    Brain Tumor Pathology 2017 34 2
  • Physiologic MRI for assessment of response to therapy and prognosis in glioblastoma
    Mark S. Shiroishi, Jerrold L. Boxerman, Whitney B. Pope
    Neuro-Oncology 2016 18 4
  • Precise ex vivo histological validation of heightened cellularity and diffusion-restricted necrosis in regions of dark apparent diffusion coefficient in 7 cases of high-grade glioma
    Peter S. LaViolette, Nikolai J. Mickevicius, Elizabeth J. Cochran, Scott D. Rand, Jennifer Connelly, Joseph A. Bovi, Mark G. Malkin, Wade M. Mueller, Kathleen M. Schmainda
    Neuro-Oncology 2014 16 12
  • Conventional and advanced magnetic resonance imaging in patients with high-grade glioma
    Whitney B. Pope, Garth Brandal
    The Quarterly Journal of Nuclear Medicine and Molecular Imaging 2018 62 3
  • Progressing Bevacizumab-Induced Diffusion Restriction Is Associated with Coagulative Necrosis Surrounded by Viable Tumor and Decreased Overall Survival in Patients with Recurrent Glioblastoma
    H.S. Nguyen, N. Milbach, S.L. Hurrell, E. Cochran, J. Connelly, J.A. Bovi, C.J. Schultz, W.M. Mueller, S.D. Rand, K.M. Schmainda, P.S. LaViolette
    American Journal of Neuroradiology 2016 37 12
  • Imaging brain tumour microstructure
    Markus Nilsson, Elisabet Englund, Filip Szczepankiewicz, Danielle van Westen, Pia C. Sundgren
    NeuroImage 2018 182
  • Restriction spectrum imaging: An evolving imaging biomarker in prostate MRI
    Ryan L. Brunsing, Natalie M. Schenker-Ahmed, Nathan S. White, J. Kellogg Parsons, Christopher Kane, Joshua Kuperman, Hauke Bartsch, Andrew Karim Kader, Rebecca Rakow-Penner, Tyler M. Seibert, Daniel Margolis, Steven S. Raman, Carrie R. McDonald, Nikdokht Farid, Santosh Kesari, Donna Hansel, Ahmed Shabaik, Anders M. Dale, David S. Karow
    Journal of Magnetic Resonance Imaging 2017 45 2
  • Advanced MRI assessment to predict benefit of anti-programmed cell death 1 protein immunotherapy response in patients with recurrent glioblastoma
    Lei Qin, Xiang Li, Amanda Stroiney, Jinrong Qu, Jeffrey Helgager, David A. Reardon, Geoffrey S. Young
    Neuroradiology 2017 59 2
  • Current standards and new concepts in MRI and PET response assessment of antiangiogenic therapies in high-grade glioma patients
    M. Hutterer, E. Hattingen, C. Palm, M. A. Proescholdt, P. Hau
    Neuro-Oncology 2015 17 6
  • Multiparametric Evaluation in Differentiating Glioma Recurrence from Treatment-Induced Necrosis Using Simultaneous18F-FDG-PET/MRI: A Single-Institution Retrospective Study
    A. Jena, S. Taneja, A. Jha, N.K. Damesha, P. Negi, G.K. Jadhav, S.M. Verma, S.K. Sogani
    American Journal of Neuroradiology 2017 38 5
  • Brain Tumors
    Lara A. Brandão, Mark S. Shiroishi, Meng Law
    Magnetic Resonance Imaging Clinics of North America 2013 21 2
  • Current emerging MRI tools for radionecrosis and pseudoprogression diagnosis
    Lucia Nichelli, Stefano Casagranda
    Current Opinion in Oncology 2021 33 6
  • Comparison of 2D (RANO) and volumetric methods for assessment of recurrent glioblastoma treated with bevacizumab—a report from the BELOB trial
    Renske Gahrmann, Martin van den Bent, Bronno van der Holt, René Michel Vernhout, Walter Taal, Maaike Vos, Jan Cees de Groot, Laurens Victor Beerepoot, Jan Buter, Zwenneke Hendrieke Flach, Monique Hanse, Bas Jasperse, Marion Smits
    Neuro-Oncology 2017 19 6
  • Comparison of ADC metrics and their association with outcome for patients with newly diagnosed glioblastoma being treated with radiation therapy, temozolomide, erlotinib and bevacizumab
    Qiuting Wen, Laleh Jalilian, Janine M. Lupo, Annette M. Molinaro, Susan M. Chang, Jennifer Clarke, Michael Prados, Sarah J. Nelson
    Journal of Neuro-Oncology 2015 121 2
  • Longitudinal Restriction Spectrum Imaging Is Resistant to Pseudoresponse in Patients with High-Grade Gliomas Treated with Bevacizumab
    P.D. Kothari, N.S. White, N. Farid, R. Chung, J.M. Kuperman, H.M. Girard, A. Shankaranarayanan, S. Kesari, C.R. McDonald, A.M. Dale
    American Journal of Neuroradiology 2013 34 9
  • Large-volume low apparent diffusion coefficient lesions predict poor survival in bevacizumab-treated glioblastoma patients
    Myron Zhang, Bryanna Gulotta, Alissa Thomas, Thomas Kaley, Sasan Karimi, Igor Gavrilovic, Kaitlin M. Woo, Zhigang Zhang, Julio Arevalo-Perez, Andrei I. Holodny, Marc Rosenblum, Robert J. Young
    Neuro-Oncology 2016 18 5
  • Recurrent high-grade glioma treated with bevacizumab: prognostic value of MGMT methylation, EGFR status and pretreatment MRI in determining response and survival
    Christina Chen, Raymond Huang, Ainsley MacLean, Alona Muzikansky, Srinivasan Mukundan, Patrick Y. Wen, Andrew D. Norden
    Journal of Neuro-Oncology 2013 115 2
  • Regorafenib CSF Penetration, Efficacy, and MRI Patterns in Recurrent Malignant Glioma Patients
    Pia S. Zeiner, Martina Kinzig, Iris Divé, Gabriele D. Maurer, Katharina Filipski, Patrick N. Harter, Christian Senft, Oliver Bähr, Elke Hattingen, Joachim P. Steinbach, Fritz Sörgel, Martin Voss, Eike Steidl, Michael W. Ronellenfitsch
    Journal of Clinical Medicine 2019 8 12
  • Advanced MR Imaging in Pediatric Brain Tumors, Clinical Applications
    Maarten Lequin, Jeroen Hendrikse
    Neuroimaging Clinics of North America 2017 27 1
  • Emerging MRI Techniques to Redefine Treatment Response in Patients With Glioblastoma
    Fabrício Guimarães Gonçalves, Sanjeev Chawla, Suyash Mohan
    Journal of Magnetic Resonance Imaging 2020 52 4
  • Apparent diffusion coefficient changes predict survival after intra-arterial bevacizumab treatment in recurrent glioblastoma
    Naveen Galla, Gloria Chiang, Shamik Chakraborty, Ranjodh Singh, A. John Tsiouris, John Boockvar, Ilhami Kovanlikaya
    Neuroradiology 2017 59 5
  • Metabolic effects of antiangiogenic drugs in tumors: Therapeutic implications
    Luigi Quintieri, Mohamed Selmy, Stefano Indraccolo
    Biochemical Pharmacology 2014 89 2
  • Sustained focal antitumor activity of bevacizumab in recurrent glioblastoma
    Oliver Bähr, Patrick N. Harter, Lutz M. Weise, Se-Jong You, Michel Mittelbronn, Michael W. Ronellenfitsch, Johannes Rieger, Joachim P. Steinbach, Elke Hattingen
    Neurology 2014 83 3
  • Multi-modal imaging of tumor cellularity and Tryptophan metabolism in human Gliomas
    Jeong-Won Jeong, Csaba Juhász, Sandeep Mittal, Edit Bosnyák, David O. Kamson, Geoffrey R. Barger, Natasha L. Robinette, William J. Kupsky, Diane C. Chugani
    Cancer Imaging 2015 15 1
  • Posttreatment Evaluation of Brain Gliomas
    Mark F. Dalesandro, Jalal B. Andre
    Neuroimaging Clinics of North America 2016 26 4
  • Challenges, limitations, and pitfalls of PET and advanced MRI in patients with brain tumors: A report of the PET/RANO group
    Norbert Galldiks, Timothy J Kaufmann, Philipp Vollmuth, Philipp Lohmann, Marion Smits, Michael C Veronesi, Karl-Josef Langen, Roberta Rudà, Nathalie L Albert, Elke Hattingen, Ian Law, Markus Hutterer, Riccardo Soffietti, Michael A Vogelbaum, Patrick Y Wen, Michael Weller, Joerg-Christian Tonn
    Neuro-Oncology 2024 26 7
  • Early response evaluation for recurrent high grade gliomas treated with bevacizumab: a volumetric analysis using diffusion-weighted imaging
    Eui Jin Hwang, Yongjun Cha, A. Leum Lee, Tae Jin Yun, Tae Min Kim, Chul-Kee Park, Ji-Hoon Kim, Chul-Ho Sohn, Sung-Hye Park, Il Han Kim, Dae Seog Heo, Se-Hoon Lee, Seung Hong Choi
    Journal of Neuro-Oncology 2013 112 3
  • Imaging biomarkers for antiangiogenic therapy in malignant gliomas
    Kevin Leu, Whitney B Pope, Timothy F Cloughesy, Albert Lai, Phioanh L Nghiemphu, Wei Chen, Linda M Liau, Benjamin M Ellingson
    CNS Oncology 2013 2 1
  • PET/MR in recurrent glioblastoma patients treated with regorafenib: [18F]FET and DWI-ADC for response assessment and survival prediction
    Giuseppe Lombardi, Alessandro Spimpolo, Sara Berti, Cristina Campi, Maria Giulia Anglani, Rossella Simeone, Laura Evangelista, Francesco Causin, Giovanni Zorzi, Giancarlo Gorgoni, Mario Caccese, Marta Padovan, Vittorina Zagonel, Diego Cecchin
    The British Journal of Radiology 2022 95 1129
  • Standard clinical approaches and emerging modalities for glioblastoma imaging
    Joshua D Bernstock, Sam E Gary, Neil Klinger, Pablo A Valdes, Walid Ibn Essayed, Hannah E Olsen, Gustavo Chagoya, Galal Elsayed, Daisuke Yamashita, Patrick Schuss, Florian A Gessler, Pier Paolo Peruzzi, Asim K Bag, Gregory K Friedman
    Neuro-Oncology Advances 2022 4 1
  • Diffusion MRI is an early biomarker of overall survival benefit in IDH wild-type recurrent glioblastoma treated with immune checkpoint inhibitors
    Akifumi Hagiwara, Talia C Oughourlian, Nicholas S Cho, Jacob Schlossman, Chencai Wang, Jingwen Yao, Catalina Raymond, Richard Everson, Kunal Patel, Sergey Mareninov, Fausto J Rodriguez, Noriko Salamon, Whitney B Pope, Phioanh L Nghiemphu, Linda M Liau, Robert M Prins, Timothy F Cloughesy, Benjamin M Ellingson
    Neuro-Oncology 2022 24 6
  • Combining diffusion and perfusion differentiates tumor from bevacizumab-related imaging abnormality (bria)
    Nikdokht Farid, Daniela B. Almeida-Freitas, Nathan S. White, Carrie R. McDonald, Joshua M. Kuperman, Abdulrahman A. Almutairi, Karra A. Muller, Scott R. VandenBerg, Santosh Kesari, Anders M. Dale
    Journal of Neuro-Oncology 2014 120 3
  • The Added Prognostic Value of Metabolic Tumor Size on FDG‐PET at First Suspected Recurrence of Glioblastoma Multiforme
    Gloria C. Chiang, Naveen Galla, Richard Ferraro, Ilhami Kovanlikaya
    Journal of Neuroimaging 2017 27 2
  • Advanced MR Imaging Techniques in Daily Practice
    Marc C. Mabray, Soonmee Cha
    Neuroimaging Clinics of North America 2016 26 4
  • Conventional and Advanced Imaging Techniques in Post-treatment Glioma Imaging
    Anna Y. Li, Michael Iv
    Frontiers in Radiology 2022 2
  • Application of Diffusion Weighted Imaging and Diffusion Tensor Imaging in the Pretreatment and Post-treatment of Brain Tumor
    Ranliang Hu, Michael J. Hoch
    Radiologic Clinics of North America 2021 59 3
  • Diffusion-weighted imaging on an MRI-linear accelerator to identify adversely prognostic tumour regions in glioblastoma during chemoradiation
    Liam S.P. Lawrence, Rachel W. Chan, Hanbo Chen, James Stewart, Mark Ruschin, Aimee Theriault, Sten Myrehaug, Jay Detsky, Pejman J. Maralani, Chia-Lin Tseng, Hany Soliman, Mary Jane Lim-Fat, Sunit Das, Greg J. Stanisz, Arjun Sahgal, Angus Z. Lau
    Radiotherapy and Oncology 2023 188
  • Posttreatment Evaluation of Central Nervous System Gliomas
    Mark S. Shiroishi, Michael T. Booker, Manyoo Agarwal, Nidhi Jain, Ilana Naghi, Alexander Lerner, Meng Law
    Magnetic Resonance Imaging Clinics of North America 2013 21 2
  • Current Clinical State of Advanced Magnetic Resonance Imaging for Brain Tumor Diagnosis and Follow Up
    Michael Iv, Byung C. Yoon, Jeremy J. Heit, Nancy Fischbein, Max Wintermark
    Seminars in Roentgenology 2018 53 1
  • Utility of intravoxel incoherent motion magnetic resonance imaging and arterial spin labeling for recurrent glioma after bevacizumab treatment
    Fuminori Miyoshi, Yuki Shinohara, Atsushi Kambe, Keita Kuya, Atsushi Murakami, Masamichi Kurosaki, Toshihide Ogawa
    Acta Radiologica 2018 59 11
  • FDA-approved machine learning algorithms in neuroradiology: A systematic review of the current evidence for approval
    Alexander G. Yearley, Caroline M.W. Goedmakers, Armon Panahi, Joanne Doucette, Aakanksha Rana, Kavitha Ranganathan, Timothy R. Smith
    Artificial Intelligence in Medicine 2023 143
  • Imaging of the Posttherapeutic Brain
    Bruno A. Telles, Francesco D’Amore, Alexander Lerner, Meng Law, Mark S. Shiroishi
    Topics in Magnetic Resonance Imaging 2015 24 3
  • Diffusion abnormalities of the corpus callosum in patients receiving bevacizumab for malignant brain tumors: suspected treatment toxicity
    Stephen F. Futterer, Alexander J. Nemeth, Sean A. Grimm, Ann B. Ragin, James P. Chandler, Kenji Muro, Maryanne H. Marymont, Jeffrey J. Raizer
    Journal of Neuro-Oncology 2014 118 1
  • Gliomas
    Whitney B. Pope, Ibrahim Djoukhadar, Alan Jackson
    2016 134
  • Multiparametric MRI and [18F]Fluorodeoxyglucose Positron Emission Tomography Imaging Is a Potential Prognostic Imaging Biomarker in Recurrent Glioblastoma
    Comron Hassanzadeh, Yuan James Rao, Anupama Chundury, Jackson Rowe, Maria Rosana Ponisio, Akash Sharma, Michelle Miller-Thomas, Christina I. Tsien, Joseph E. Ippolito
    Frontiers in Oncology 2017 7
  • Bevacizumab: radiation combination produces restricted diffusion on brain MRI
    John R Hesselink, Matthew J Barkovich, Tyler M Seibert, Nikdokht Farid, Karra A Muller, Kevin T Murphy, Santosh Kesari
    CNS Oncology 2014 3 5
  • Bevacizumab-induced Coagulative Necrosis with Restricted Diffusion
    Amit Agarwal, Amit Desai, Vivek Gupta, Prasanna Vibhute
    Radiology: Imaging Cancer 2022 4 5
  • Evaluation of the malignant potential of gliomas using diffusion-weighted and gadolinium-enhanced magnetic resonance imaging
    Yoshinori Takaya, Hui Chen, Hirotomo TEN, Katsumi Hoya, Chuan-lu Jiang, Ken-ichi Oyama, Keisuke Onoda, Akira Matsuno
    Brain Science Advances 2021 7 4
  • Modification of MRI pattern of high‐grade glioma pseudoprogression in regorafenib therapy
    Mariam Mansour, Valerio Vitale, Giuseppe Lombardi, Giulio Riva, Francesca Pancheri, Mariano Zanusso
    Journal of Medical Imaging and Radiation Oncology 2022 66 3
  • Multimodal imaging findings in patients with glioblastoma with extensive coagulative necrosis related to regorafenib
    Jan-Michael Werner, Michael M Wollring, Caroline Tscherpel, Elena K Rosen, Lisa Werr, Isabelle Stetter, Daniel Rueß, Maximilian I Ruge, Anna Brunn, Abdulkader Al Shughri, Christoph Kabbasch, Gereon R Fink, Karl-Josef Langen, Norbert Galldiks
    Neuro-Oncology 2023 25 6
  • Neuroimaging and Genetic Influence in Treating Brain Neoplasms
    L. Celso Hygino da Cruz, Margareth Kimura
    Neuroimaging Clinics of North America 2015 25 1
  • Transforming approaches to treating TRK fusion cancer: historical comparison of larotrectinib and histology-specific therapies
    Megan Pollack, Karen Keating, Erika Wissinger, Louis Jackson, Evelyn Sarnes, Brian Cuffel
    Current Medical Research and Opinion 2021 37 1
  • Magnetic Resonance Imaging of Glioma in the Era of Antiangiogenic Therapy
    Sarah N. Khan, Michael Linetsky, Benjamin M. Ellingson, Whitney B. Pope
    PET Clinics 2013 8 2
  • Assessing Biological Response to Bevacizumab Using 18F-Fluoromisonidazole PET/MR Imaging in a Patient with Recurrent Anaplastic Astrocytoma
    Ramon F. Barajas, Miguel H. Pampaloni, Jennifer L. Clarke, Youngho Seo, Dragana Savic, Randall A. Hawkins, Spencer C. Behr, Susan M. Chang, Mitchel Berger, William P. Dillon, Soonmee Cha
    Case Reports in Radiology 2015 2015
  • Association of Diffusion and Anatomic Imaging Parameters with Survival for Patients with Newly Diagnosed Glioblastoma Participating in Two Different Clinical Trials
    Qiuting Wen, Laleh Jalilian, Janine M. Lupo, Yan Li, Ritu Roy, Annette M. Molinaro, Susan M. Chang, Michael Prados, Nicholas Butowski, Jennifer Clarke, Sarah J. Nelson
    Translational Oncology 2015 8 6
  • Diagnostic Accuracy of Centrally Restricted Diffusion Sign in Cerebral Metastatic Disease: Differentiating Radiation Necrosis from Tumor Recurrence
    Paulo Puac-Polanco, Nader Zakhari, Jacob Miller, David McComiskey, Rebecca E. Thornhill, Gerard H. Jansen, Vimoj J Nair, Thanh Binh Nguyen
    Canadian Association of Radiologists Journal 2023 74 1
  • Diffusion restriction in a non-enhancing metastatic brain tumor treated with bevacizumab — recurrent tumor or atypical necrosis?
    Lakshmanan Sivasundaram, Saman Hazany, Naveed Wagle, Gabriel Zada, Thomas C. Chen, Alexander Lerner, John L. Go, Francesco D'Amore, Meng Law, Mark S. Shiroishi
    Clinical Imaging 2014 38 5
  • Radiographic patterns of recurrence and pathologic correlation in malignant gliomas treated with bevacizumab
    Alissa Thomas, Marc Rosenblum, Sasan Karimi, Lisa M DeAngelis, Antonio Omuro, Thomas J Kaley
    CNS Oncology 2018 7 1
  • Early assessment of recurrent glioblastoma response to bevacizumab treatment by diffusional kurtosis imaging: a preliminary report
    Chu-Yu Lee, Amandeep Kalra, Maria V Spampinato, Ali Tabesh, Jens H Jensen, Joseph A Helpern, Maria de Fatima Falangola, Mark H Van Horn, Pierre Giglio
    The Neuroradiology Journal 2019 32 5
  • The relationship between radiation dose and bevacizumab-related imaging abnormality in patients with brain tumors: A voxel-wise normal tissue complication probability (NTCP) analysis
    Mia Salans, Jordan Houri, Roshan Karunamuni, Austin Hopper, Rachel Delfanti, Tyler M. Seibert, Naeim Bahrami, Yasamin Sharifzadeh, Carrie McDonald, Anders Dale, Vitali Moiseenko, Nikdokht Farid, Jona A. Hattangadi-Gluth, Michael C Burger
    PLOS ONE 2023 18 2
  • The utility of arterial spin labeling imaging for predicting prognosis after a recurrence of high-grade glioma in patients under bevacizumab treatment
    Atsushi Kambe, Shinichiro Kitao, Ryoya Ochiai, Tomohiro Hosoya, Shinya Fujii, Masamichi Kurosaki
    Journal of Neuro-Oncology 2024 166 1
  • Functional Neuroradiology
    Shah Islam, Melanie A. Morrison, Adam D. Waldman
    2023
  • Glioma Imaging
    Peter S. LaViolette
    2020
  • Neurology
    Jeremy Rees, Robert Bradford, Sebastian Brandner, Naomi Fersht, Rolf Jäger, Elena Wilson
    2016
  • Response Assessment of Bevacizumab for Treatment of Malignant Glioma by Neuroimaging
    Keisuke Miyake, Takashi Tamiya
    Japanese Journal of Neurosurgery 2016 25 11
  • Adult CNS Radiation Oncology
    Mihir D. Shanker, Timothy J. Kaufmann, Caroline Chung
    2024
  • Advanced Neuroradiology Cases
    2016
  • Advanced imaging characterization of post-chemoradiation glioblastoma stratified by diffusion MRI phenotypes known to predict favorable anti-VEGF response
    Francesco Sanvito, Irina Kryukov, Jingwen Yao, Ashley Teraishi, Catalina Raymond, John Gao, Cole Miller, Phioanh L. Nghiemphu, Albert Lai, Linda M. Liau, Kunal Patel, Richard G. Everson, Blaine S.C. Eldred, Robert M. Prins, David A. Nathanson, Noriko Salamon, Timothy F. Cloughesy, Benjamin M. Ellingson
    Journal of Neuro-Oncology 2025
  • Advanced neuroimaging techniques for diagnosis and treatment evaluation in neuro-oncology
    Bernhard Schuknecht, Krisztina Baráth, Silvia Hofer
    memo - Magazine of European Medical Oncology 2012 5 3
  • Auf dem Weg zu mehr Präzision in der Hirntumortherapie
    A. Radbruch, E. Hattingen
    Der Nervenarzt 2015 86 6
  • Brain Tumor Imaging
    Peter Raab, Heinrich Lanfermann
    2015
  • Comprehensive Overview of Modern Surgical Approaches to Intrinsic Brain Tumors
    William Clifton, Bryson Hauck, Vivek Gupta
    2019
  • Diffusion basis spectrum imaging as an adjunct to conventional MRI leads to earlier diagnosis of high-grade glioma tumor progression versus treatment effect
    Rowland H Han, Tanner M Johanns, Kaleigh F Roberts, Yu Tao, Jingqin Luo, Zezhong Ye, Peng Sun, Jacob Blum, Tsen-Hsuan Lin, Sheng-Kwei Song, Albert H Kim
    Neuro-Oncology Advances 2023 5 1
  • Functional Imaging in Oncology
    L. Celso Hygino da Cruz, Raquel Ribeiro Batista, Claudio de Carvalho Rangel
    2014
  • Functional Neuroradiology
    Juan Márquez, Thiparom Sananmuang, Ashok Srinivasan, Pamela W. Schaefer, Reza Forghani
    2023
  • Glioblastoma
    James Eric Schmitt, Joel M. Stein
    2016
  • Handbook of Neuro-Oncology Neuroimaging
    Diogo Goulart Corrêa, Luiz Celso Hygino da Cruz
    2022
  • Handbook of Neuro-Oncology Neuroimaging
    Geoffrey S. Young, Jinrong Qu, Lei Qin
    2022
  • High Field Brain MRI
    Antonella Bacci, Gianluca Marucci, Caterina Budai, Federico Sacchetti, Raffaele Agati
    2017
  • Mechanism and significance of diffusion restriction followed by calcification in high-grade glioma treated with bevacizumab
    Tomohiro Hosoya, Atsushi Kambe, Irfan Kesumayadi, Karen Makishima, Shuntaro Sueyoshi, Makoto Sakamoto, Masamichi Kurosaki
    Scientific Reports 2024 14 1
  • Relative cerebral blood volume as response predictor in the treatment of recurrent glioblastoma with anti-angiogenic therapy
    Michele Breda-Yepes, Luis A. Rodríguez-Hernández, Enrique Gómez-Figueroa, Michel G. Mondragón-Soto, Gerardo Arellano-Flores, Alan Hernández-Hernández, Héctor A. Rodríguez-Rubio, Pablo Martínez, Ignacio Reyes-Moreno, Juan A. Álvaro-Heredia, Guillermo A. Gutiérrez Aceves, Eliezer Villanueva-Castro, Marcos V. Sangrador-Deitos, Mario Alonso-Vanegas, Vicente Guerrero-Juárez, Alberto González-Aguilar
    Clinical Neurology and Neurosurgery 2023 233
  • The Use of Apparent Diffusion Coefficient Values for Differentiating Bevacizumab-Related Cytotoxicity from Tumor Recurrence and Radiation Necrosis in Glioblastoma
    Kamand Khalaj, Michael A. Jacobs, Jay-Jiguang Zhu, Yoshua Esquenazi, Sigmund Hsu, Nitin Tandon, Alireza Akhbardeh, Xu Zhang, Roy Riascos, Arash Kamali
    Cancers 2024 16 13
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 33 (9)
American Journal of Neuroradiology
Vol. 33, Issue 9
1 Oct 2012
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Persistent Diffusion-Restricted Lesions in Bevacizumab-Treated Malignant Gliomas Are Associated with Improved Survival Compared with Matched Controls
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
S. Mong, B.M. Ellingson, P.L. Nghiemphu, H.J. Kim, L. Mirsadraei, A. Lai, W. Yong, T.M. Zaw, T.F. Cloughesy, W.B. Pope
Persistent Diffusion-Restricted Lesions in Bevacizumab-Treated Malignant Gliomas Are Associated with Improved Survival Compared with Matched Controls
American Journal of Neuroradiology Oct 2012, 33 (9) 1763-1770; DOI: 10.3174/ajnr.A3053

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Persistent Diffusion-Restricted Lesions in Bevacizumab-Treated Malignant Gliomas Are Associated with Improved Survival Compared with Matched Controls
S. Mong, B.M. Ellingson, P.L. Nghiemphu, H.J. Kim, L. Mirsadraei, A. Lai, W. Yong, T.M. Zaw, T.F. Cloughesy, W.B. Pope
American Journal of Neuroradiology Oct 2012, 33 (9) 1763-1770; DOI: 10.3174/ajnr.A3053
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Response Assessment in Neuro-Oncology Criteria for Gliomas: Practical Approach Using Conventional and Advanced Techniques
  • Multiparametric Evaluation in Differentiating Glioma Recurrence from Treatment-Induced Necrosis Using Simultaneous 18F-FDG-PET/MRI: A Single-Institution Retrospective Study
  • Progressing Bevacizumab-Induced Diffusion Restriction Is Associated with Coagulative Necrosis Surrounded by Viable Tumor and Decreased Overall Survival in Patients with Recurrent Glioblastoma
  • Lessons From Anti-Vascular Endothelial Growth Factor and Anti-Vascular Endothelial Growth Factor Receptor Trials in Patients With Glioblastoma
  • Diffusion-Weighted Imaging in Cancer: Physical Foundations and Applications of Restriction Spectrum Imaging
  • Sustained focal antitumor activity of bevacizumab in recurrent glioblastoma
  • Longitudinal Restriction Spectrum Imaging Is Resistant to Pseudoresponse in Patients with High-Grade Gliomas Treated with Bevacizumab
  • Crossref (87)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Diffusion-Weighted Imaging in Cancer: Physical Foundations and Applications of Restriction Spectrum Imaging
    Nathan S. White, Carrie R. McDonald, Niky Farid, Josh Kuperman, David Karow, Natalie M. Schenker-Ahmed, Hauke Bartsch, Rebecca Rakow-Penner, Dominic Holland, Ahmed Shabaik, Atle Bjørnerud, Tuva Hope, Jona Hattangadi-Gluth, Michael Liss, J. Kellogg Parsons, Clark C. Chen, Steve Raman, Daniel Margolis, Robert E. Reiter, Leonard Marks, Santosh Kesari, Arno J. Mundt, Christopher J. Kane, Bob S. Carter, William G. Bradley, Anders M. Dale
    Cancer Research 2014 74 17
  • Metastatic Disease of the Nervous System
    Whitney B. Pope
    2018 149
  • Lessons From Anti–Vascular Endothelial Growth Factor and Anti–Vascular Endothelial Growth Factor Receptor Trials in Patients With Glioblastoma
    Christine Lu-Emerson, Dan G. Duda, Kyrre E. Emblem, Jennie W. Taylor, Elizabeth R. Gerstner, Jay S. Loeffler, Tracy T. Batchelor, Rakesh K. Jain
    Journal of Clinical Oncology 2015 33 10
  • Response Assessment in Neuro-Oncology Criteria for Gliomas: Practical Approach Using Conventional and Advanced Techniques
    D.J. Leao, P.G. Craig, L.F. Godoy, C.C. Leite, B. Policeni
    American Journal of Neuroradiology 2020 41 1
  • Advanced imaging techniques for neuro-oncologic tumor diagnosis, with an emphasis on PET-MRI imaging of malignant brain tumors
    Wynton B. Overcast, Korbin M. Davis, Chang Y. Ho, Gary D. Hutchins, Mark A. Green, Brian D. Graner, Michael C. Veronesi
    Current Oncology Reports 2021 23 3
  • Bevacizumab for malignant gliomas: current indications, mechanisms of action and resistance, and markers of response
    Ryota Tamura, Toshihide Tanaka, Keisuke Miyake, Kazunari Yoshida, Hikaru Sasaki
    Brain Tumor Pathology 2017 34 2
  • Physiologic MRI for assessment of response to therapy and prognosis in glioblastoma
    Mark S. Shiroishi, Jerrold L. Boxerman, Whitney B. Pope
    Neuro-Oncology 2016 18 4
  • Precise ex vivo histological validation of heightened cellularity and diffusion-restricted necrosis in regions of dark apparent diffusion coefficient in 7 cases of high-grade glioma
    Peter S. LaViolette, Nikolai J. Mickevicius, Elizabeth J. Cochran, Scott D. Rand, Jennifer Connelly, Joseph A. Bovi, Mark G. Malkin, Wade M. Mueller, Kathleen M. Schmainda
    Neuro-Oncology 2014 16 12
  • Conventional and advanced magnetic resonance imaging in patients with high-grade glioma
    Whitney B. Pope, Garth Brandal
    The Quarterly Journal of Nuclear Medicine and Molecular Imaging 2018 62 3
  • Progressing Bevacizumab-Induced Diffusion Restriction Is Associated with Coagulative Necrosis Surrounded by Viable Tumor and Decreased Overall Survival in Patients with Recurrent Glioblastoma
    H.S. Nguyen, N. Milbach, S.L. Hurrell, E. Cochran, J. Connelly, J.A. Bovi, C.J. Schultz, W.M. Mueller, S.D. Rand, K.M. Schmainda, P.S. LaViolette
    American Journal of Neuroradiology 2016 37 12

More in this TOC Section

  • SWI or T2*: Which MRI Sequence to Use in the Detection of Cerebral Microbleeds? The Karolinska Imaging Dementia Study
  • Progression of Microstructural Damage in Spinocerebellar Ataxia Type 2: A Longitudinal DTI Study
  • Usefulness of Quantitative Susceptibility Mapping for the Diagnosis of Parkinson Disease
Show more Brain

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editors Choice
  • Fellow Journal Club
  • Letters to the Editor

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

Special Collections

  • Special Collections

Resources

  • News and Updates
  • Turn around Times
  • Submit a Manuscript
  • Author Policies
  • Manuscript Submission Guidelines
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Submit a Case
  • Become a Reviewer/Academy of Reviewers
  • Get Peer Review Credit from Publons

Multimedia

  • AJNR Podcast
  • AJNR SCANtastic
  • Video Articles

About Us

  • About AJNR
  • Editorial Board
  • Not an AJNR Subscriber? Join Now
  • Alerts
  • Feedback
  • Advertise with us
  • Librarian Resources
  • Permissions
  • Terms and Conditions

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire