Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Other Publications
    • ajnr

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

Welcome to the new AJNR, Updated Hall of Fame, and more. Read the full announcements.


AJNR is seeking candidates for the position of Associate Section Editor, AJNR Case Collection. Read the full announcement.

 

Research ArticleInterventional

Thrombosis Heralding Aneurysmal Rupture: An Exploration of Potential Mechanisms in a Novel Giant Swine Aneurysm Model

J. Raymond, T.E. Darsaut, M. Kotowski, A. Makoyeva, G. Gevry, F. Berthelet and I. Salazkin
American Journal of Neuroradiology February 2013, 34 (2) 346-353; DOI: https://doi.org/10.3174/ajnr.A3407
J. Raymond
aFrom the Department of Radiology (J.R.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
T.E. Darsaut
bInterventional Neuroradiology Research Laboratory (T.E.D., M.K., A.M., G.G., I.S.)
dDivision of Neurosurgery (T.E.D.), Department of Surgery, University of Alberta Hospital, Mackenzie Health Sciences Centre, Edmonton, Alberta, Canada.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. Kotowski
bInterventional Neuroradiology Research Laboratory (T.E.D., M.K., A.M., G.G., I.S.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
A. Makoyeva
bInterventional Neuroradiology Research Laboratory (T.E.D., M.K., A.M., G.G., I.S.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
G. Gevry
bInterventional Neuroradiology Research Laboratory (T.E.D., M.K., A.M., G.G., I.S.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
F. Berthelet
cDepartment of Pathology (F.B.), Centre Hospitalier de l'Université de Montréal, Notre-Dame Hospital, Montreal, Quebec, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
I. Salazkin
bInterventional Neuroradiology Research Laboratory (T.E.D., M.K., A.M., G.G., I.S.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

Article Information

vol. 34 no. 2 346-353
DOI 
https://doi.org/10.3174/ajnr.A3407
PubMed 
23153870

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received December 14, 2011
  • Accepted after revision May 16, 2012
  • Published online February 13, 2013.

Copyright & Usage 
© 2013 by American Journal of Neuroradiology

Author Information

  1. J. Raymonda,
  2. T.E. Darsautb,d,
  3. M. Kotowskib,
  4. A. Makoyevab,
  5. G. Gevryb,
  6. F. Bertheletc and
  7. I. Salazkinb
  1. aFrom the Department of Radiology (J.R.)
  2. bInterventional Neuroradiology Research Laboratory (T.E.D., M.K., A.M., G.G., I.S.)
  3. cDepartment of Pathology (F.B.), Centre Hospitalier de l'Université de Montréal, Notre-Dame Hospital, Montreal, Quebec, Canada
  4. dDivision of Neurosurgery (T.E.D.), Department of Surgery, University of Alberta Hospital, Mackenzie Health Sciences Centre, Edmonton, Alberta, Canada.
  1. Please address correspondence to Jean Raymond, MD, CHUM–Notre-Dame Hospital, Interventional Neuroradiology, 1560 Sherbrooke East, Pavilion Simard, Room Z12909, Montreal, Quebec, Canada H2L 4M1; e-mail: jean.raymond{at}umontreal.ca
View Full Text

Altmetrics

Cited By...

  • 30 Citations
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Flow Diversion in Middle Cerebral Artery Aneurysms: Is It Really an All-Purpose Treatment?
    Osman Melih Topcuoglu, Erol Akgul, Ergun Daglioglu, Elif Dilara Topcuoglu, Ahmet Peker, Ilkay Akmangit, Deniz Belen, Anil Arat
    World Neurosurgery 2016 87
  • Recurrence of endovascularly and microsurgically treated intracranial aneurysms—review of the putative role of aneurysm wall biology
    Serge Marbacher, Mika Niemelä, Juha Hernesniemi, Juhana Frösén
    Neurosurgical Review 2019 42 1
  • In vivo cerebral aneurysm models
    John W. Thompson, Omar Elwardany, David J. McCarthy, Dallas L. Sheinberg, Carlos M. Alvarez, Ahmed Nada, Brian M. Snelling, Stephanie H. Chen, Samir Sur, Robert M. Starke
    Neurosurgical Focus 2019 47 1
  • Testing flow diversion in animal models: a systematic review
    Robert Fahed, Jean Raymond, Célina Ducroux, Jean-Christophe Gentric, Igor Salazkin, Daniela Ziegler, Guylaine Gevry, Tim E. Darsaut
    Neuroradiology 2016 58 4
  • Aneurysm Rupture after Endovascular Flow Diversion: The Possible Role of Persistent Flows through the Transition Zone Associated with Device Deformation
    T.E. Darsaut, E. Rayner-Hartley, A. Makoyeva, I. Salazkin, F. Berthelet, J. Raymond
    Interventional Neuroradiology 2013 19 2
  • Intraluminal Cell Transplantation Prevents Growth and Rupture in a Model of Rupture-Prone Saccular Aneurysms
    Serge Marbacher, Juhana Frösén, Johan Marjamaa, Andrey Anisimov, Petri Honkanen, Michael von Gunten, Usama Abo-Ramadan, Juha Hernesniemi, Mika Niemelä
    Stroke 2014 45 12
  • Trends in Cerebrovascular Surgery
    Takayuki Hara, Shintaro Arai, Yoshiaki Goto, Tsuguhito Takizawa, Tatsuya Uchida
    2016 123
  • Usefulness of the Pipeline Embolic Device for Large and Giant Carotid Cavernous Aneurysms
    Shigeru Miyachi, Ryo Hiramatsu, Hiroyuki Ohnishi, Ryokichi Yagi, Toshihiko Kuroiwa
    Neurointervention 2017 12 2
  • Flow Diversion of Giant Curved Sidewall and Bifurcation Experimental Aneurysms with Very-Low-Porosity Devices
    Tim E. Darsaut, Fabrice Bing, Alina Makoyeva, Guylaine Gevry, Igor Salazkin, Jean Raymond
    World Neurosurgery 2014 82 6
  • Innovations in Endovascular Treatment Strategies for Large Carotid Cavernous Aneurysms—The Safety and Efficacy of a Flow Diverter
    Shigeru Miyachi, Hiroyuki Ohnishi, Ryo Hiramatsu, Takashi Izumi, Noriaki Matsubara, Toshihiko Kuroiwa
    Journal of Stroke and Cerebrovascular Diseases 2017 26 5
  • Saccular Aneurysm Models Featuring Growth and Rupture: A Systematic Review
    Serge Marbacher, Stefan Wanderer, Fabio Strange, Basil E. Grüter, Javier Fandino
    Brain Sciences 2020 10 2
  • MR Imaging of Myeloperoxidase Activity in a Model of the Inflamed Aneurysm Wall
    M. J. Gounis, I. M. J. van der Bom, A. K. Wakhloo, S. Zheng, J.- Y. Chueh, A. L. Kuhn, A. A. Bogdanov
    American Journal of Neuroradiology 2015 36 1
  • Very large and giant microsurgical bifurcation aneurysms in rabbits: Proof of feasibility and comparability using computational fluid dynamics and biomechanical testing
    Camillo Sherif, Erwin Herbich, Roberto Plasenzotti, Helga Bergmeister, Ursula Windberger, Georg Mach, Gerhard Sommer, Gerhard A. Holzapfel, Thomas Haider, Martin Krssak, Guenther Kleinpeter
    Journal of Neuroscience Methods 2016 268
  • Flow diversion: what can clinicians learn from animal models?
    Robert Fahed, Tim E. Darsaut, Jean-Christophe Gentric, Behzad Farzin, Igor Salazkin, Guylaine Gevry, Jean Raymond
    Neuroradiology 2017 59 3
  • Reduced Activity of von Willebrand Factor after Flow-Diverting Stent Implantation for Intracranial Aneurysms: A Link to Acquired von Willebrand Disease?
    I. Oran, C. Cinar, H. Bozkaya, M. Parildar, S. Duman
    American Journal of Neuroradiology 2020 41 1
  • In situ decellularization of a large animal saccular aneurysm model: sustained inflammation and active aneurysm wall remodeling
    Robert M King, Jildaz Caroff, Erin T Langan, Anita Leporati, Aurora Rodriguez-Rodriguez, Christopher M Raskett, Suresh Gupta, Ajit S Puri, Peter Caravan, Matthew J Gounis, Alexei A Bogdanov, Jr.
    Journal of NeuroInterventional Surgery 2021 13 3
  • Activated Platelet-Homing Nanoplatform for Targeting Magnetic Resonance Imaging of Aneurysm-Related Thrombus in Rabbits
    Yang Zhang, Sijie Cheng, Yu He, Chaojie Tang, Feng Liu, Yun Sun, Shuo Zhao, Greta S. P. Mok, Hong Yang, Zhiguo Zhou, Wu Wang
    ACS Applied Materials & Interfaces 2021 13 43
  • Advances in Stroke
    Ajay K. Wakhloo, Matthew J. Gounis, Ju-Yu Chueh, Laurent Pierot
    Stroke 2014 45 2
  • Aneurysmal and Perianeurysmal Changes After Endovascular Treatment: from Inflammation to Microbleed. A Case Report
    L. Cirillo, F. Toni, M. Dall’Olio, C. Princiotta, M. Leonardi
    Clinical Neuroradiology 2016 26 2
  • Flow Diverter for Large Carotid Cavernous Aneurysms
    Shigeru MIYACHI, Hiroyuki OHNISHI, Ryo HIRAMATSU, Ryokichi YAGI, Toshihiko KUROIWA
    Surgery for Cerebral Stroke 2018 46 1
  • Intracranial aneurysm thrombosis precipitated by iodine injection may herald its rupture
    L. Calviere, F. Bonneville, T. Geeraerts, D. Brauge, C. Cognard, J.M. Olivot
    Revue Neurologique 2021 177 3
  • Secondary Histomorphological Changes in Cerebral Arteries of Normotensive and Hypertensive Rats following a Carotid-Jugular Fistula Induction
    Keith Ng, Masakazu Higurashi, Nahoko Uemiya, Yi Qian, Jeroen Hendrikse
    PLoS ONE 2014 9 3
  • Treatment of Complex Large or Thrombosed Cerebral Aneurysms
    Takayuki HARA, Tohru MIZUTANI
    Surgery for Cerebral Stroke 2016 44 2
  • Cardiovascular Thrombus
    Gemma Vilahur, Soumaya Ben-Aicha, Lina Badimon
    2018
  • Flow-diverting stent and delayed intracranial bleeding: the case for discussing acquired von Willebrand disease
    Ismail Oran
    Platelets 2021 32 3
  • Imaging of intracranial aneurysms in animals: a systematic review of modalities
    Anne F. Cayron, Sandrine Morel, Eric Allémann, Philippe Bijlenga, Brenda R. Kwak
    Neurosurgical Review 2023 46 1
  • Stroke
    Ajay K. Wakhloo, Matthew J. Gounis, Francesco Massari, Ajit S. Puri
    2016
  • Computational Neurosurgery
    Camillo Sherif, Gerhard Sommer, Peter Schiretz, Gerhard A. Holzapfel
    2024 1462
  • Evaluating Animal Models of Arteriovenous Malformation and Intracerebral Aneurysm: A Mechanistic Approach
    Dominic Franceschelli, Arianna D. Carfora, Blake T. Holthaus, Mayur S. Patel, Shahid M. Nimjee
    Stroke: Vascular and Interventional Neurology 2025
  • The surgical strategy and technical nuances of in situ side-to-side bypass for the management of complex intracranial aneurysms
    Hua-wei Wang, Zhe Xue, Cai-hong Sun, Dong-sheng Kong, Chen Wu, Zheng-hui Sun
    Frontiers in Neurology 2023 14
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 34 (2)
American Journal of Neuroradiology
Vol. 34, Issue 2
1 Feb 2013
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Thrombosis Heralding Aneurysmal Rupture: An Exploration of Potential Mechanisms in a Novel Giant Swine Aneurysm Model
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
J. Raymond, T.E. Darsaut, M. Kotowski, A. Makoyeva, G. Gevry, F. Berthelet, I. Salazkin
Thrombosis Heralding Aneurysmal Rupture: An Exploration of Potential Mechanisms in a Novel Giant Swine Aneurysm Model
American Journal of Neuroradiology Feb 2013, 34 (2) 346-353; DOI: 10.3174/ajnr.A3407

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Thrombosis Heralding Aneurysmal Rupture: An Exploration of Potential Mechanisms in a Novel Giant Swine Aneurysm Model
J. Raymond, T.E. Darsaut, M. Kotowski, A. Makoyeva, G. Gevry, F. Berthelet, I. Salazkin
American Journal of Neuroradiology Feb 2013, 34 (2) 346-353; DOI: 10.3174/ajnr.A3407
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • In situ decellularization of a large animal saccular aneurysm model: sustained inflammation and active aneurysm wall remodeling
  • Reduced Activity of von Willebrand Factor after Flow-Diverting Stent Implantation for Intracranial Aneurysms: A Link to Acquired von Willebrand Disease?
  • MR Imaging of Myeloperoxidase Activity in a Model of the Inflamed Aneurysm Wall
  • Intraluminal Cell Transplantation Prevents Growth and Rupture in a Model of Rupture-Prone Saccular Aneurysms
  • Advances in Stroke: Advances in Interventional Radiology 2013
  • Crossref (30)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Flow Diversion in Middle Cerebral Artery Aneurysms: Is It Really an All-Purpose Treatment?
    Osman Melih Topcuoglu, Erol Akgul, Ergun Daglioglu, Elif Dilara Topcuoglu, Ahmet Peker, Ilkay Akmangit, Deniz Belen, Anil Arat
    World Neurosurgery 2016 87
  • Recurrence of endovascularly and microsurgically treated intracranial aneurysms—review of the putative role of aneurysm wall biology
    Serge Marbacher, Mika Niemelä, Juha Hernesniemi, Juhana Frösén
    Neurosurgical Review 2019 42 1
  • In vivo cerebral aneurysm models
    John W. Thompson, Omar Elwardany, David J. McCarthy, Dallas L. Sheinberg, Carlos M. Alvarez, Ahmed Nada, Brian M. Snelling, Stephanie H. Chen, Samir Sur, Robert M. Starke
    Neurosurgical Focus 2019 47 1
  • Testing flow diversion in animal models: a systematic review
    Robert Fahed, Jean Raymond, Célina Ducroux, Jean-Christophe Gentric, Igor Salazkin, Daniela Ziegler, Guylaine Gevry, Tim E. Darsaut
    Neuroradiology 2016 58 4
  • Aneurysm Rupture after Endovascular Flow Diversion: The Possible Role of Persistent Flows through the Transition Zone Associated with Device Deformation
    T.E. Darsaut, E. Rayner-Hartley, A. Makoyeva, I. Salazkin, F. Berthelet, J. Raymond
    Interventional Neuroradiology 2013 19 2
  • Intraluminal Cell Transplantation Prevents Growth and Rupture in a Model of Rupture-Prone Saccular Aneurysms
    Serge Marbacher, Juhana Frösén, Johan Marjamaa, Andrey Anisimov, Petri Honkanen, Michael von Gunten, Usama Abo-Ramadan, Juha Hernesniemi, Mika Niemelä
    Stroke 2014 45 12
  • Trends in Cerebrovascular Surgery
    Takayuki Hara, Shintaro Arai, Yoshiaki Goto, Tsuguhito Takizawa, Tatsuya Uchida
    2016 123
  • Usefulness of the Pipeline Embolic Device for Large and Giant Carotid Cavernous Aneurysms
    Shigeru Miyachi, Ryo Hiramatsu, Hiroyuki Ohnishi, Ryokichi Yagi, Toshihiko Kuroiwa
    Neurointervention 2017 12 2
  • Flow Diversion of Giant Curved Sidewall and Bifurcation Experimental Aneurysms with Very-Low-Porosity Devices
    Tim E. Darsaut, Fabrice Bing, Alina Makoyeva, Guylaine Gevry, Igor Salazkin, Jean Raymond
    World Neurosurgery 2014 82 6
  • Innovations in Endovascular Treatment Strategies for Large Carotid Cavernous Aneurysms—The Safety and Efficacy of a Flow Diverter
    Shigeru Miyachi, Hiroyuki Ohnishi, Ryo Hiramatsu, Takashi Izumi, Noriaki Matsubara, Toshihiko Kuroiwa
    Journal of Stroke and Cerebrovascular Diseases 2017 26 5

More in this TOC Section

  • SAVE vs. Solumbra Techniques for Thrombectomy
  • CT Perfusion&Reperfusion in Acute Ischemic Stroke
  • Delayed Reperfusion Post-Thrombectomy&Thrombolysis
Show more Interventional

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editors Choice
  • Fellow Journal Club
  • Letters to the Editor

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

Special Collections

  • Special Collections

Resources

  • News and Updates
  • Turn around Times
  • Submit a Manuscript
  • Author Policies
  • Manuscript Submission Guidelines
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Submit a Case
  • Become a Reviewer/Academy of Reviewers
  • Get Peer Review Credit from Publons

Multimedia

  • AJNR Podcast
  • AJNR SCANtastic
  • Video Articles

About Us

  • About AJNR
  • Editorial Board
  • Not an AJNR Subscriber? Join Now
  • Alerts
  • Feedback
  • Advertise with us
  • Librarian Resources
  • Permissions
  • Terms and Conditions

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire