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MRA Versus DSA for Follow-Up of Coiled Intracranial Aneurysms: A Meta-Analysis

M.J. van Amerongen, H.D. Boogaarts, J. de Vries, A.L.M. Verbeek, F.J.A. Meijer, M. Prokop and R.H.M.A. Bartels
American Journal of Neuroradiology September 2014, 35 (9) 1655-1661; DOI: https://doi.org/10.3174/ajnr.A3700
M.J. van Amerongen
aFrom the Departments of Neurosurgery (M.J.v.A., H.D.B., J.d.V., R.H.M.A.B.)
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H.D. Boogaarts
aFrom the Departments of Neurosurgery (M.J.v.A., H.D.B., J.d.V., R.H.M.A.B.)
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J. de Vries
aFrom the Departments of Neurosurgery (M.J.v.A., H.D.B., J.d.V., R.H.M.A.B.)
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A.L.M. Verbeek
bEpidemiology and Biostatistics (A.L.M.V.)
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F.J.A. Meijer
cRadiology/Neuroradiology (F.J.A.M., M.P.), Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
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M. Prokop
cRadiology/Neuroradiology (F.J.A.M., M.P.), Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
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R.H.M.A. Bartels
aFrom the Departments of Neurosurgery (M.J.v.A., H.D.B., J.d.V., R.H.M.A.B.)
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Abstract

SUMMARY: MR angiography is proposed as a safer and less expensive alternative to the reference standard, DSA, in the follow-up of intracranial aneurysms treated with endovascular coil occlusion. We performed a systematic review and meta-analysis to evaluate the accuracy of TOF-MRA and contrast-enhanced MRA in detecting residual flow in the follow-up of coiled intracranial aneurysms. Literature was reviewed through the PubMed, Cochrane, and EMBASE data bases. In comparison with DSA, the sensitivity of TOF-MRA was 86% (95% CI: 82–89%), with a specificity of 84% (95% CI: 81–88%), for the detection of any recurrent flow. For contrast-enhanced MRA, the sensitivity and specificity were 86% (95% CI: 82–89%) and 89% (95% CI: 85–92%), respectively. Both TOF-MRA and contrast-enhanced MRA are shown to be highly accurate for detection of any recanalization in intracranial aneurysms treated with endovascular coil occlusion.

ABBREVIATIONS:

CE
contrast-enhanced
GRADE
grades of recommendation, assessment, development, and evaluation
SROC
summary receiver operating characteristic
  • © 2014 by American Journal of Neuroradiology

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American Journal of Neuroradiology: 35 (9)
American Journal of Neuroradiology
Vol. 35, Issue 9
1 Sep 2014
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M.J. van Amerongen, H.D. Boogaarts, J. de Vries, A.L.M. Verbeek, F.J.A. Meijer, M. Prokop, R.H.M.A. Bartels
MRA Versus DSA for Follow-Up of Coiled Intracranial Aneurysms: A Meta-Analysis
American Journal of Neuroradiology Sep 2014, 35 (9) 1655-1661; DOI: 10.3174/ajnr.A3700

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MRA Versus DSA for Follow-Up of Coiled Intracranial Aneurysms: A Meta-Analysis
M.J. van Amerongen, H.D. Boogaarts, J. de Vries, A.L.M. Verbeek, F.J.A. Meijer, M. Prokop, R.H.M.A. Bartels
American Journal of Neuroradiology Sep 2014, 35 (9) 1655-1661; DOI: 10.3174/ajnr.A3700
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