Article Figures & Data
Figures
- Fig 1.
Distribution of lesions in MR imaging–positive cases.
- Fig 2.
MR images of the brain of a 25-year-old woman with antepartum eclampsia. A, FLAIR MR image shows edema involving the cortex and subcortical white matter of the bilateral occipital and parietal regions and the splenium of the corpus callosum. B, DWI shows hyperintensity in corresponding areas. C, ADC image shows hyperintensity in the bilateral occipital and parietal regions but hypointensity in the splenium of the corpus callosum.
- Fig 3.
FLAIR MR images of the brain of a 19-year-old woman with antepartum eclampsia showing involvement of bilateral frontal, parietal (A), and cerebellar (B) regions.
- Fig 4.
Brain MR images of a 20-year-old woman with early postpartum eclampsia. A, FLAIR MR image shows edema involving the bilateral frontal and parietal regions. FLAIR (B), DWI (C), and ADC (D) show involvement of the right thalamus with cytotoxic edema.
Tables
Parameters 95% Confidence Interval P Value Lower Upper Systolic blood pressure −0.09 0.07 .87 Diastolic blood pressure −0.08 0.14 .56 Serum UA −0.19 0.83 .22 Serum LDH 0.00 0.02 .26 Serum creatinine −3.12 2.33 .78 - Table 2:
Comparison of demographic data, clinical features, and laboratory data between MRI-positive and MRI-negative patients
MRI-Positive (n = 27) MRI-Negative (n = 8) OR 95% CI P Value Lower Upper Age (yr) 24.44 ± 3.53 23.87 ± 2.47 – −2.16 3.30 .67 Headache 19 5 1.42 0.27 7.44 1.00 Altered sensorium 26 4 26.0 2.29 295.65 .006a Visual disturbances 17 1 11.9 1.27 111.36 .018a Focal deficit 3 0 – – – 1.00 Status epilepticus 13 0 – – – .015a Edema in feet 15 5 0.75 0.15 3.79 1.00 SBP (mm Hg) 164.52 ± 17.03 153.75 ± 14.07 – −2.70 24.24 .11 DBP (mm Hg) 102.81 ± 12.71 98.75 ± 9.91 – −5.90 14.03 .41 MBP (mm Hg) 123.85 ± 13.39 117.25 ± 9.80 – −3.81 17.01 .21 Hematocrit (%) 32.33 ± 6.76 32.58 ± 6.49 – −5.73 5.25 .93 MCV (fL) 88.97 ± 6.02 91.1 ± 6.17 – −7.08 2.83 .39 TLC (109/L) 7.83 ± 2.23 8.41 ± 2.00 – −2.37 1.20 .51 Plt (105/mm3) 1.85 ± 0.49 2.00 ± 0.29 – −0.52 0.22 .42 AST (IU/L) 47.15 ± 17.83 53.13 ± 15.22 – −20.15 8.20 .40 ALT (IU/L) 46.48 ± 16.12 53.13 ± 16.14 – −19.85 6.56 .32 Sr. Creatinine (mg/dL) 1.11 ± 0.41 0.74 ± 0.14 – 0.07 0.67 .019a Sr. UA (mg/dL) 9.47 ± 2.75 6.31 ± 0.76 – 1.14 5.17 .003a Sr. LDH (IU/L) 458.03 ± 107.94 319.50 ± 20.50 – 59.69 217.39 .001a Note:—SBP indicates systolic blood pressure; DBP, diastolic blood pressure; MBP, mean blood pressure; MCV, mean corpuscular volume; TLC, total leukocyte count; Plt, platelet count; AST, aspartate transaminase; ALT, alanine transaminase; Sr., serum.
↵a Significant.
- Table 3:
Comparison of demographic data, clinical features, and laboratory data of cases with respect to outcome
Survived (n = 29) Deceased (n = 6) OR 95% CI P Value Lower Upper Age (yr) 23.86 ± 2.76 26.50 ± 4.93 – –5.55 0.27 .07 Headache 19 5 0.38 0.04 3.713 .64 Altered sensorium 24 6 – – – .56 Visual disturbances 14 4 0.47 0.07 2.96 .66 Focal deficit 1 2 0.07 0.01 0.98 .07 Status epilepticus 12 1 3.53 0.36 34.19 .38 Edema in feet 16 4 0.62 0.10 3.91 .68 SBP (mm Hg) 159.72 ± 17.52 173.33 ± 5.16 – −28.45 1.23 .07 DBP (mm Hg) 100.55 ± 11.35 108.33 ± 14.72 – −18.66 3.10 .16 MBP (mm Hg) 120.76 ± 12.79 130 ± 10.95 – −20.76 2.19 .11 Hematocrit (%) 32.76 ± 6.42 30.53 ± 7.79 – −3.82 8.31 .46 MCV (fL) 89.94 ± 5.86 87.12 ± 6.84 – −2.67 8.32 .30 TLC (109/L) 8.02 ± 2.31 7.65 ± 1.33 – −1.62 2.38 .70 Plt (105/mm3) 1.88 ± 0.49 1.88 ± 0.20 – −0.41 0.43 .96 AST (IU/L) 50.17 ± 18.09 40.50 ± 9.75 – −5.93 25.27 .22 ALT (IU/L) 47.66 ± 17.44 49.67 ± 7.99 – −16.94 12.92 .79 Sr. Creatinine (mg/dL) 0.88 ± 0.26 1.72 ± 0.07 – −1.06 .62 <.001a Sr. UA (mg/dL) 7.89 ± 1.54 12.87 ± 3.78 – −6.84 −3.10 <.001a Sr. LDH (IU/L) 404.44 ± 109.06 532.33 ± 44.68 – −220.90 −34.85 .009a Positive MRI findings 21 6 – – – .30 Moderate and severe PRES 5 4 0.10 0.02 0.73 .027a Cytotoxic edema 7 2 0.64 0.10 4.25 .64 Note:—SBP indicates systolic blood pressure; DBP, diastolic blood pressure; MBP, mean blood pressure; MCV, mean corpuscular volume; TLC, total leukocyte count; Plt, platelet count; AST, aspartate transaminase; ALT, alanine transaminase; Sr., serum.
↵a Significant.
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