Middle Cerebral Artery Stenosis in Patients with Acute Ischemic Stroke and TIA in Israel

Article Figures & Data

Table 1:

Distribution of demographic and vascular risk factors and vascular diseases in the whole group of patients^{^a}

Risk Factor	All Patients (N = 1344)	Patients with Intracranial Stenosis	Patients without Intracranial Stenosis	P Value
Age	65.67 ± 13.2	66.02 ± 12.9	63.85 ± 12.9	<.04
Sex (male)	983 (73.1%)	81 (67.5%)	902 (67.2%)	.14
Ethnicity (Arab)	310 (23.1%)	23 (19.1%)	287 (23.5%)	.28
CVA	1041 (77.5%)	107 (89.2%)	934 (76.3%)	.0005
TIA	303 (22.5%)	13 (10.8%)	290 (23.8%)	.0005
Hypertension	946 (70.4%)	93 (77.5%)	853 (69.8%)	.068
Diabetes	470 (35%)	61 (50.8%)	409 (33.5%)	.0002
Hyperlipidemia	686 (51%)	72 (60%)	614 (50.25%)	.04
Smoking	454 (33.8%)	32 (26.7%)	422 (34.5%)	.07
IHD	398 (29.6%)	42 (35%)	356 (29.1%)	.18
MI	187 (13.9%)	17 (14.2%)	170 (13.9%)	.9
AF	138 (10.3%)	8 (6.7%)	130 (10.6%)	.14
PVD	94 (7%)	17 (14.2%)	77 (6.3%)	.004

Note:—CVA indicates cerebral vascular accident; IHD, ischemic heart disease; AF, paroxysmal or chronic atrial fibrillation; PVD, peripheral vascular disease; MI, myocardial infarction.
↵a χ² analyses and t tests, uncorrected for multiple comparisons, were performed.

Table 2:

Logistic regression analysis of possible predictors of intracranial stenosis in patients with acute ischemic stroke or TIA^{^a}

Effect	Odds Ratio	95% Confidence Limits	P Value
Ethnicity (Arab vs Jewish)	0.785	0.479–1.284	.33
Age (per yr)	1.009	0.992–1.026	.3
Sex (male vs female)	0.715	0.466–1.097	.124
Hypertension	1.138	0.709–1.826	.59
Diabetes	1.889	1.274–2.801	.002^{^b}
Smoking	0.723	0.460–1.137	.16
Hyperlipidemia	1.352	0.899–2.033	.15
IHD	1.243	0.746–2.071	.4
PVD	2.197	1.210–3.987	.01^{^b}
MI	0.736	0.381–1.423	.36
AF	0.582	0.272–1.247	.16

Note:—IHD indicates ischemic heart disease; AF, paroxysmal or chronic atrial fibrillation; PVD, peripheral vascular disease; MI, myocardial infarction.
↵a Multivariate logistic regression analysis of factors potentially leading to intracranial stenosis. The overall logistic regression model was significant, P = .0003.
↵b Significant parameters.