Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Other Publications
    • ajnr

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

Welcome to the new AJNR, Updated Hall of Fame, and more. Read the full announcements.


AJNR is seeking candidates for the position of Associate Section Editor, AJNR Case Collection. Read the full announcement.

 

Research ArticleAdult Brain
Open Access

Validation of Zero TE–MRA in the Characterization of Cerebrovascular Diseases: A Feasibility Study

S. Shang, J. Ye, W. Dou, X. Luo, J. Qu, Q. Zhu, H. Zhang and J. Wu
American Journal of Neuroradiology September 2019, 40 (9) 1484-1490; DOI: https://doi.org/10.3174/ajnr.A6173
S. Shang
aFrom the Department of Radiology (S.S., J.Y., X.L., Q.Z., H.Z., J.W.), Clinical Medical College, Yangzhou University, Yangzhou, Jiangsu, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for S. Shang
J. Ye
aFrom the Department of Radiology (S.S., J.Y., X.L., Q.Z., H.Z., J.W.), Clinical Medical College, Yangzhou University, Yangzhou, Jiangsu, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for J. Ye
W. Dou
bMR Research China (W.D., J.Q.), GE Healthcare, Beijing China.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for W. Dou
X. Luo
aFrom the Department of Radiology (S.S., J.Y., X.L., Q.Z., H.Z., J.W.), Clinical Medical College, Yangzhou University, Yangzhou, Jiangsu, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for X. Luo
J. Qu
bMR Research China (W.D., J.Q.), GE Healthcare, Beijing China.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for J. Qu
Q. Zhu
aFrom the Department of Radiology (S.S., J.Y., X.L., Q.Z., H.Z., J.W.), Clinical Medical College, Yangzhou University, Yangzhou, Jiangsu, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Q. Zhu
H. Zhang
aFrom the Department of Radiology (S.S., J.Y., X.L., Q.Z., H.Z., J.W.), Clinical Medical College, Yangzhou University, Yangzhou, Jiangsu, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for H. Zhang
J. Wu
aFrom the Department of Radiology (S.S., J.Y., X.L., Q.Z., H.Z., J.W.), Clinical Medical College, Yangzhou University, Yangzhou, Jiangsu, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for J. Wu
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

Article Figures & Data

Figures

  • Tables
  • Fig 1.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 1.

    Coronal projection of stenosis in the right MCA M2 segment (a 74-year-old man). A stenosis (34%, grade 2) was observed on VR of CTA (A, white arrowhead) and on VR of zTE-MRA (B, white arrowhead); the stenosis (32%, grade 2) was equal to that on CTA. The stenosis on VR of TOF (C, white arrowhead) was overestimated (72%, grade 3). In correspondence with MIP of CTA (D, white arrowhead), flow signal in the stenosis lesion was homogeneous on MIP of zTE-MRA (E, white arrowhead, score 4) and was heterogeneous on TOF-MRA (F, white arrowhead, score 3).

  • Fig 2.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 2.

    Oblique projection of aneurysms in the right ICA siphon segment (a 63-year-old woman). Two aneurysms were found on VR of CTA (A): The diameters were 3.0 × 3.2 mm (white arrow) and 2.4 × 2.1 mm (white arrowhead), respectively. Equal findings were observed on VR of zTE (B, 3.3 × 3.5 mm, white arrow; 2.× 2.4 mm, white arrowhead). On VR of TOF-MRA (C), the large one (3.1 × 3.4 mm, white arrow) was equal to the one on CTA. However, the tiny one was not evident (1.5 × 1.4 mm, white arrowhead). Concerning MIP of CTA (D, white arrow and white arrowhead), the same results were observed on MIP of zTE-MRA (E, white arrow and white arrowhead) and TOF-MRA (F, white arrow and white arrowhead).

  • Fig 3.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 3.

    An AVM in the left MCA M1 segment (a 27-year-old man). For the AVM, the nidus (blue arrow), draining vein (white arrowhead), and venous sinus (transverse sinus and sigmoid sinus, white arrow) were clearly depicted on VR and MIP of CTA (A and B) and zTE-MRA (C and D), whereas they were not well-defined (nidus, blue arrow; draining vein, white arrowhead) and were missed (venous sinus) on VR and MIP of TOF-MRA (E and F).

  • Fig 4.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 4.

    Oblique projection of Moyamoya disease in the left MCA M1 segment (a 43-year-old woman). The stenosed MCA (white arrowhead) and developed collateral vessels (white arrow) were scanned on VR and MIP of CTA (A and B) and zTE-MRA (C and D). A false occlusion in MCA (white arrowhead) and ill-defined collateral vessels (white arrow) were seen on VR and MIP of TOF-MRA (E and F).

Tables

  • Figures
    • View popup
    Table 1:

    Parameters of MRA sequences

    TR/TE (ms)Flip AngleFOV (cm)MatrixThickness (mm)SlicesNEXBandwidth (kHz)SlabsLabel Duration (sec)CoverageTime (min:sec)
    zTE-MRA862/0.0163°15 × 15166 × 1661.2320131.25–2Calvarium-mandible5:48
    TOF-MRA25/3.415°30 × 24320 × 2561.4256141.673–Cingulate cortex–mesencephalon5:08
    • Note:— –indicates no data available; TR, repetition time; TE, echo time; FOV, field of view; NEX, number of excitation.

    • View popup
    Table 2:

    Parameters of CTA sequences

    CollimationPitchFOV (cm)Gantry Rotation Time (ms)Thickness (mm)SlicesTube Voltage (kV[peak])Tube Current (mAs)Dose-Length Product (mGy × cm)Coverage
    CTA128 × 0.6250.75817 × 174000.6715100–120100–450220–608Aortic arch–vertex
    • View popup
    Table 3:

    Intensity of sound levels in different modes for zTE-MRA and TOF-MRA

    ModeSound Level (dB)FP
    Ambient54.89 ± 0.41a11,824.06<.001
    zTE-MRA58.01 ± 0.32ab
    TOF-MRA92.86 ± 0.64b
    • ↵a A significant difference compared with the TOF-MRA mode.

    • ↵b A significant difference compared with the ambient mode.

    • View popup
    Table 4:

    Cross-table of stenosis grade from observers for zTE-MRA (n = 44)a

    zTE-MRA A GradezTE-MRA B Grade
    01234Total
    0100001 (2.27%)
    10730010 (22.73%)
    200140014 (31.82%)
    30048012 (27.27%)
    4000167 (15.91%)
    Total1 (2.27%)7 (15.91%)21 (47.73%)9 (20.45%)6 (13.64%)44
    • ↵a Grading criterion: NASCET. Data represent the number of cases. A and B are observers A and B.

    • View popup
    Table 5:

    Cross-table of stenosis grade from observers for TOF-MRA (n = 44)a

    TOF-MRA A GradeTOF-MRA B Grade
    01234Total
    0000000 (0.00%)
    11900010 (22.73%)
    20184013(29.55%)
    30047011 (25.00%)
    40002810 (22.73%)
    Total1 (2.27%)10 (22.73%)12 (27.27%)13 (29.55%)8 (18.18%)44
    • ↵a Grading criterion: NASCET. Data represent the number of cases. A and B are observers A and B.

    • View popup
    Table 6:

    Classification of stenosis grade from observers for zTE-MRA, TOF-MRA, and CTA (n = 44)a

    Stenosis GradezTE-MRATOF-MRACTA
    01 (2.27%)0 (0.00%)1 (2.27%)
    111 (25.00%)10 (22.73%)11 (25.00%)
    212 (27.27%)12 (27.27%)13 (29.55%)
    311 (25.00%)11 (25.00%)10 (22.73%)
    49 (20.45%)11 (25.00%)9 (20.45%)
    • ↵a Grading criterion: NASCET. Data represent the number of cases.

    • View popup
    Table 7:

    Statistical analyses of aneurysms measured on MRA for groups

    GroupMRASumraIntercept (95% CI)bSlope (95% CI)bICC
    Group tinyczTE150.84−0.5084–1.1794−0.4952–0.20930.83; 95% CI, 0.57–0.94
    TOF150.740.7000–2.6133−1.0344 to −0.19230.64; 95% CI, 0.21–0.86
    Group largedzTE230.98−0.6059–0.2130−0.02625–0.12000.98, 95% CI, 0.97–0.99
    TOF230.95−1.1571–0.3062−0.01380–0.25200.95, 95% CI, 0.89–0.98
    • Note:—ICC indicates intraclass correlation coefficient.

    • ↵a Pearson correlation coefficient.

    • ↵b Intercept and slope are by Bland-Altman analysis.

    • ↵c Group tiny ≤3 mm.

    • ↵d Group large >3 mm.

PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 40 (9)
American Journal of Neuroradiology
Vol. 40, Issue 9
1 Sep 2019
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Validation of Zero TE–MRA in the Characterization of Cerebrovascular Diseases: A Feasibility Study
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
S. Shang, J. Ye, W. Dou, X. Luo, J. Qu, Q. Zhu, H. Zhang, J. Wu
Validation of Zero TE–MRA in the Characterization of Cerebrovascular Diseases: A Feasibility Study
American Journal of Neuroradiology Sep 2019, 40 (9) 1484-1490; DOI: 10.3174/ajnr.A6173

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Validation of Zero TE–MRA in the Characterization of Cerebrovascular Diseases: A Feasibility Study
S. Shang, J. Ye, W. Dou, X. Luo, J. Qu, Q. Zhu, H. Zhang, J. Wu
American Journal of Neuroradiology Sep 2019, 40 (9) 1484-1490; DOI: 10.3174/ajnr.A6173
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Footnotes
    • REFERENCES
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Crossref (5)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Qualitative and quantitative analysis of 3D T1 Silent imaging
    Francesca Di Giuliano, Silvia Minosse, Eliseo Picchi, Valentina Ferrazzoli, Valerio Da Ros, Massimo Muto, Chiara Adriana Pistolese, Francesco Garaci, Roberto Floris
    La radiologia medica 2021 126 9
  • Use of PETRA-MRA to assess intracranial arterial stenosis: Comparison with TOF-MRA, CTA, and DSA
    Junxia Niu, Yuncai Ran, Rui Chen, Feifei Zhang, Xiaowen Lei, Xiao Wang, Tengfei Li, Jinxia Zhu, Yong Zhang, Jingliang Cheng, Yan Zhang, Chengcheng Zhu
    Frontiers in Neurology 2023 13
  • The Use of Pointwise Encoding Time Reduction With Radial Acquisition MRA to Assess Middle Cerebral Artery Stenosis Pre- and Post-stent Angioplasty: Comparison With 3D Time-of-Flight MRA and DSA
    Feifei Zhang, Yuncai Ran, Ming Zhu, Xiaowen Lei, Junxia Niu, Xiao Wang, Yong Zhang, Shujian Li, Jinxia Zhu, Xuemei Gao, Mahmud Mossa-Basha, Jingliang Cheng, Chengcheng Zhu
    Frontiers in Cardiovascular Medicine 2021 8
  • CT-Like Images from MRI: A Comprehensive Review of the Zero-Echo-Time Sequence
    Yesim Yekta Yuruk, Mehmet Simsar, Yeliz Pekcevik
    Applied Radiology 2025 54 Suppl_1
  • Visualization of cortical neoangiogenesis after combined revascularization surgery in moyamoya disease using silent MRA
    Tomoaki Suzuki, Hitoshi Hasegawa, Hidemoto Fujiwara, Kohei Shibuya, Kouichirou Okamoto, Makoto Oishi
    Neuroradiology 2025 67 2

More in this TOC Section

  • Diagnostic Neuroradiology of Monoclonal Antibodies
  • Segmentation of Brain Metastases with BLAST
  • NCCT vs. MRI for Brain Atrophy in Acute Stroke
Show more Adult Brain

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editors Choice
  • Fellow Journal Club
  • Letters to the Editor

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

Special Collections

  • Special Collections

Resources

  • News and Updates
  • Turn around Times
  • Submit a Manuscript
  • Author Policies
  • Manuscript Submission Guidelines
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Submit a Case
  • Become a Reviewer/Academy of Reviewers
  • Get Peer Review Credit from Publons

Multimedia

  • AJNR Podcast
  • AJNR SCANtastic
  • Video Articles

About Us

  • About AJNR
  • Editorial Board
  • Not an AJNR Subscriber? Join Now
  • Alerts
  • Feedback
  • Advertise with us
  • Librarian Resources
  • Permissions
  • Terms and Conditions

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire