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Research ArticleAdult Brain

Diagnostic Accuracy of Arterial Spin-Labeling, Dynamic Contrast-Enhanced, and DSC Perfusion Imaging in the Diagnosis of Recurrent High-Grade Gliomas: A Prospective Study

T.B. Nguyen, N. Zakhari, S. Velasco Sandoval, A. Guarnizo-Capera, M. Alexios Gulak, J. Woulfe, G. Jansen, R. Thornhill, N. Majtenyi and G.O. Cron
American Journal of Neuroradiology February 2023, 44 (2) 134-142; DOI: https://doi.org/10.3174/ajnr.A7771
T.B. Nguyen
aFrom the Department of Radiology (T.B.N., N.Z., R.T.), Radiation Oncology and Medical Physics
cUniversity of Ottawa (T.B.N., N.Z., J.W., G.J., R.T.), Ottawa, Ontario, Canada
dThe Ottawa Hospital Research Institute (T.B.N., J.W., G.J., R.T.), Ottawa, Ontario, Canada
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  • ORCID record for T.B. Nguyen
N. Zakhari
aFrom the Department of Radiology (T.B.N., N.Z., R.T.), Radiation Oncology and Medical Physics
cUniversity of Ottawa (T.B.N., N.Z., J.W., G.J., R.T.), Ottawa, Ontario, Canada
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S. Velasco Sandoval
eDivision of Neuroradiology (S.V.S., A.G.-C.), Department of Radiology, Hospital Universitario Fundación Santa Fe de Bogotá, Bogotá, D.C., Colombia
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A. Guarnizo-Capera
eDivision of Neuroradiology (S.V.S., A.G.-C.), Department of Radiology, Hospital Universitario Fundación Santa Fe de Bogotá, Bogotá, D.C., Colombia
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M. Alexios Gulak
fDepartment of Anesthesiology and Pain Medicine (M.A.G.), University of Toronto, Toronto, Ontario, Canada
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J. Woulfe
bDepartment of Pathology and Laboratory Medicine (J.W., G.J.), The Ottawa Hospital, Ottawa, Ontario, Canada
cUniversity of Ottawa (T.B.N., N.Z., J.W., G.J., R.T.), Ottawa, Ontario, Canada
dThe Ottawa Hospital Research Institute (T.B.N., J.W., G.J., R.T.), Ottawa, Ontario, Canada
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G. Jansen
bDepartment of Pathology and Laboratory Medicine (J.W., G.J.), The Ottawa Hospital, Ottawa, Ontario, Canada
cUniversity of Ottawa (T.B.N., N.Z., J.W., G.J., R.T.), Ottawa, Ontario, Canada
dThe Ottawa Hospital Research Institute (T.B.N., J.W., G.J., R.T.), Ottawa, Ontario, Canada
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R. Thornhill
aFrom the Department of Radiology (T.B.N., N.Z., R.T.), Radiation Oncology and Medical Physics
cUniversity of Ottawa (T.B.N., N.Z., J.W., G.J., R.T.), Ottawa, Ontario, Canada
dThe Ottawa Hospital Research Institute (T.B.N., J.W., G.J., R.T.), Ottawa, Ontario, Canada
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N. Majtenyi
gDepartment of Medical Physics (N.M.), Grand River Regional Cancer Centre, Kitchener, Ontario, Canada
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G.O. Cron
hStanford University (G.O.C.), Stanford, California
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Article Information

vol. 44 no. 2 134-142
DOI 
https://doi.org/10.3174/ajnr.A7771
PubMed 
36702501

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received July 28, 2022
  • Accepted after revision December 30, 2022
  • Published online February 1, 2023.

Copyright & Usage 
© 2023 by American Journal of Neuroradiology

Author Information

  1. T.B. Nguyena,c,d,
  2. N. Zakharia,c,
  3. S. Velasco Sandovale,
  4. A. Guarnizo-Caperae,
  5. M. Alexios Gulakf,
  6. J. Woulfeb,c,d,
  7. G. Jansenb,c,d,
  8. R. Thornhilla,c,d,
  9. N. Majtenyig and
  10. G.O. Cronh
  1. aFrom the Department of Radiology (T.B.N., N.Z., R.T.), Radiation Oncology and Medical Physics
  2. bDepartment of Pathology and Laboratory Medicine (J.W., G.J.), The Ottawa Hospital, Ottawa, Ontario, Canada
  3. cUniversity of Ottawa (T.B.N., N.Z., J.W., G.J., R.T.), Ottawa, Ontario, Canada
  4. dThe Ottawa Hospital Research Institute (T.B.N., J.W., G.J., R.T.), Ottawa, Ontario, Canada
  5. eDivision of Neuroradiology (S.V.S., A.G.-C.), Department of Radiology, Hospital Universitario Fundación Santa Fe de Bogotá, Bogotá, D.C., Colombia
  6. fDepartment of Anesthesiology and Pain Medicine (M.A.G.), University of Toronto, Toronto, Ontario, Canada
  7. gDepartment of Medical Physics (N.M.), Grand River Regional Cancer Centre, Kitchener, Ontario, Canada
  8. hStanford University (G.O.C.), Stanford, California
  1. Please address correspondence to Thanh B. Nguyen, MD, Department of Radiology, The Ottawa Hospital, Civic Campus, 1053 Carling Ave, Room J1115, Ottawa, ON, K1Y 4E9, Canada; e-mail: thnguyen{at}toh.ca
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Funding

  • GE Healthcare

    ISR 2016-0425

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T.B. Nguyen, N. Zakhari, S. Velasco Sandoval, A. Guarnizo-Capera, M. Alexios Gulak, J. Woulfe, G. Jansen, R. Thornhill, N. Majtenyi, G.O. Cron
Diagnostic Accuracy of Arterial Spin-Labeling, Dynamic Contrast-Enhanced, and DSC Perfusion Imaging in the Diagnosis of Recurrent High-Grade Gliomas: A Prospective Study
American Journal of Neuroradiology Feb 2023, 44 (2) 134-142; DOI: 10.3174/ajnr.A7771

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MRI for Recurrent High-Grade Gliomas Diagnosis
T.B. Nguyen, N. Zakhari, S. Velasco Sandoval, A. Guarnizo-Capera, M. Alexios Gulak, J. Woulfe, G. Jansen, R. Thornhill, N. Majtenyi, G.O. Cron
American Journal of Neuroradiology Feb 2023, 44 (2) 134-142; DOI: 10.3174/ajnr.A7771
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Cited By...

  • Arterial Spin-Labeling and DSC Perfusion Metrics Improve Agreement in Neuroradiologists Clinical Interpretations of Posttreatment High-Grade Glioma Surveillance MR Imaging--An Institutional Experience
  • Crossref (6)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • MRI Treatment Response Assessment Maps (TRAMs) for differentiating recurrent glioblastoma from radiation necrosis
    Sebastian Johannes Müller, Eya Khadhraoui, Oliver Ganslandt, Hans Henkes, Georg Alexander Gihr
    Journal of Neuro-Oncology 2024 166 3
  • The value of arterial spin labelling (ASL) perfusion MRI in the assessment of post-treatment progression in adult glioma: A systematic review and meta-analysis.
    Tamadur A Alsulami, Harpreet Hyare, David L Thomas, Xavier Golay
    Neuro-Oncology Advances 2023 5 1
  • Arterial Spin-Labeling and DSC Perfusion Metrics Improve Agreement in Neuroradiologists’ Clinical Interpretations of Posttreatment High-Grade Glioma Surveillance MR Imaging—An Institutional Experience
    Ghiam Yamin, Eric Tranvinh, Bryan A. Lanzman, Elizabeth Tong, Syed S. Hashmi, Chirag B. Patel, Michael Iv
    American Journal of Neuroradiology 2024 45 4
  • ASL, DSC, DCE perfusion MRI and 18F-DOPA PET/CT in differentiating glioma recurrence from post-treatment changes
    Giulia Moltoni, Andrea Romano, Gabriela Capriotti, Giuseppe Campagna, Anna Maria Ascolese, Allegra Romano, Francesco Dellepiane, Giuseppe Minniti, Alberto Signore, Alessandro Bozzao
    La radiologia medica 2024 129 9
  • Cerebellar Cavernoma Resection: Case Report with Long-Term Follow-Up
    Corneliu Toader, Matei Serban, Razvan-Adrian Covache-Busuioc, Mugurel Petrinel Radoi, Ghaith Saleh Radi Aljboor, Horia Petre Costin, Antonio Daniel Corlatescu, Luca-Andrei Glavan, Radu Mircea Gorgan
    Journal of Clinical Medicine 2024 13 24
  • A Combined Approach Using T2*-Weighted Dynamic Susceptibility Contrast MRI Perfusion Parameters and Radiomics to Differentiate Between Radionecrosis and Glioma Progression: A Proof-of-Concept Study
    José Pablo Martínez Barbero, Francisco Javier Pérez García, David López Cornejo, Marta García Cerezo, Paula María Jiménez Gutiérrez, Luis Balderas, Miguel Lastra, Antonio Arauzo-Azofra, José M. Benítez, Antonio Jesús Láinez Ramos-Bossini
    Life 2025 15 4

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