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Research ArticleUltra-High-Field MRI/Imaging of Epilepsy/Demyelinating Diseases/Inflammation/Infection

Multiparametric Characterization and Spatial Distribution of Different MS Lesion Phenotypes

Francesco Tazza, Giacomo Boffa, Simona Schiavi, Caterina Lapucci, Gian Franco Piredda, Emilio Cipriano, Domenico Zacà, Luca Roccatagliata, Tom Hilbert, Tobias Kober, Matilde Inglese and Mauro Costagli
American Journal of Neuroradiology August 2024, 45 (8) 1166-1174; DOI: https://doi.org/10.3174/ajnr.A8271
Francesco Tazza
aFrom the Departments of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (F.T., G.B., S.S., E.C., M.I., M.C.), University of Genoa, Genoa, Italy
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  • ORCID record for Francesco Tazza
Giacomo Boffa
aFrom the Departments of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (F.T., G.B., S.S., E.C., M.I., M.C.), University of Genoa, Genoa, Italy
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  • ORCID record for Giacomo Boffa
Simona Schiavi
aFrom the Departments of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (F.T., G.B., S.S., E.C., M.I., M.C.), University of Genoa, Genoa, Italy
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Caterina Lapucci
bIstituto di Ricovero e Cura a Carattere Scientifico (C.L., L.R., M.I., M.C.), Ospedale Policlinico San Martino, Genoa, Italy
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Gian Franco Piredda
cAdvanced Clinical Imaging Technology (G.F.P., T.H., T.K.), Siemens Healthineers International AG, Lausanne, Switzerland
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Emilio Cipriano
aFrom the Departments of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (F.T., G.B., S.S., E.C., M.I., M.C.), University of Genoa, Genoa, Italy
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Domenico Zacà
fSiemens Healthcare (D.Z.), Milan, Italy
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Luca Roccatagliata
bIstituto di Ricovero e Cura a Carattere Scientifico (C.L., L.R., M.I., M.C.), Ospedale Policlinico San Martino, Genoa, Italy
gDepartment of Health Sciences (L.R.), University of Genoa, Genoa, Italy
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Tom Hilbert
cAdvanced Clinical Imaging Technology (G.F.P., T.H., T.K.), Siemens Healthineers International AG, Lausanne, Switzerland
dDepartment of Radiology (T.H., T.K.), Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland
eLTS5 (T.H., T.K.), École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
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Tobias Kober
cAdvanced Clinical Imaging Technology (G.F.P., T.H., T.K.), Siemens Healthineers International AG, Lausanne, Switzerland
dDepartment of Radiology (T.H., T.K.), Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland
eLTS5 (T.H., T.K.), École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
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Matilde Inglese
aFrom the Departments of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (F.T., G.B., S.S., E.C., M.I., M.C.), University of Genoa, Genoa, Italy
bIstituto di Ricovero e Cura a Carattere Scientifico (C.L., L.R., M.I., M.C.), Ospedale Policlinico San Martino, Genoa, Italy
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Mauro Costagli
aFrom the Departments of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (F.T., G.B., S.S., E.C., M.I., M.C.), University of Genoa, Genoa, Italy
bIstituto di Ricovero e Cura a Carattere Scientifico (C.L., L.R., M.I., M.C.), Ospedale Policlinico San Martino, Genoa, Italy
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Article Information

vol. 45 no. 8 1166-1174
DOI 
https://doi.org/10.3174/ajnr.A8271
PubMed 
38816021

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received December 14, 2023
  • Accepted after revision March 1, 2024
  • Published online August 9, 2024.

Copyright & Usage 
© 2024 by American Journal of Neuroradiology

Author Information

  1. Francesco Tazzaa,#,
  2. Giacomo Boffaa,#,
  3. Simona Schiavia,
  4. Caterina Lapuccib,
  5. Gian Franco Pireddac,
  6. Emilio Ciprianoa,
  7. Domenico Zacàf,
  8. Luca Roccatagliatab,g,
  9. Tom Hilbertc,d,e,
  10. Tobias Koberc,d,e,
  11. Matilde Inglesea,b and
  12. Mauro Costaglia,b
  1. aFrom the Departments of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (F.T., G.B., S.S., E.C., M.I., M.C.), University of Genoa, Genoa, Italy
  2. bIstituto di Ricovero e Cura a Carattere Scientifico (C.L., L.R., M.I., M.C.), Ospedale Policlinico San Martino, Genoa, Italy
  3. cAdvanced Clinical Imaging Technology (G.F.P., T.H., T.K.), Siemens Healthineers International AG, Lausanne, Switzerland
  4. dDepartment of Radiology (T.H., T.K.), Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland
  5. eLTS5 (T.H., T.K.), École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
  6. fSiemens Healthcare (D.Z.), Milan, Italy
  7. gDepartment of Health Sciences (L.R.), University of Genoa, Genoa, Italy
  1. Please address correspondence to Matilde Inglese, MD, Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Largo Paolo Daneo 3, 16132 Genova, Italy; e-mail: m.inglese{at}unige.it
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Funding

  • Ministero della Salute

    Ricerca Corrente RRC 2022 and 5x1000
  • Ministero dell’Università e della Ricerca

    National Recovery and Resilience Plan (NRRP); project MNESYS (PE0000006)

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This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Biomarkers of Progression Independent of Relapse Activity—Can We Actually Measure It Yet?
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    International Journal of Molecular Sciences 2025 26 10
  • Cognitive changes in patients with relapse-free MS treated with high efficacy therapies: the predictive value of paramagnetic rim lesions
    Vincenzo Daniele Boccia, Elisa Leveraro, Emilio Cipriano, Caterina Lapucci, Tommaso Sirito, Maria Cellerino, Giacomo Rebella, Lorenza Nasone, Giacomo Boffa, Matilde Inglese
    Journal of Neurology, Neurosurgery & Psychiatry 2025
  • Lesion phenotyping based on magnetic susceptibility in pediatric multiple sclerosis
    Vincenzo Daniele Boccia, Giacomo Boffa, Caterina Lapucci, Mauro Costagli, Luca Bosisio, Maria Margherita Mancardi, Matilde Inglese, Maria Cellerino
    Journal of Neuroimaging 2024 34 5
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Vol. 45, Issue 8
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Cite this article
Francesco Tazza, Giacomo Boffa, Simona Schiavi, Caterina Lapucci, Gian Franco Piredda, Emilio Cipriano, Domenico Zacà, Luca Roccatagliata, Tom Hilbert, Tobias Kober, Matilde Inglese, Mauro Costagli
Multiparametric Characterization and Spatial Distribution of Different MS Lesion Phenotypes
American Journal of Neuroradiology Aug 2024, 45 (8) 1166-1174; DOI: 10.3174/ajnr.A8271

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Multiparametric MS Lesion Phenotypes
Francesco Tazza, Giacomo Boffa, Simona Schiavi, Caterina Lapucci, Gian Franco Piredda, Emilio Cipriano, Domenico Zacà, Luca Roccatagliata, Tom Hilbert, Tobias Kober, Matilde Inglese, Mauro Costagli
American Journal of Neuroradiology Aug 2024, 45 (8) 1166-1174; DOI: 10.3174/ajnr.A8271
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This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Biomarkers of Progression Independent of Relapse Activity—Can We Actually Measure It Yet?
    Gabriel Bsteh, Assunta Dal-Bianco, Nik Krajnc, Thomas Berger
    International Journal of Molecular Sciences 2025 26 10
  • Cognitive changes in patients with relapse-free MS treated with high efficacy therapies: the predictive value of paramagnetic rim lesions
    Vincenzo Daniele Boccia, Elisa Leveraro, Emilio Cipriano, Caterina Lapucci, Tommaso Sirito, Maria Cellerino, Giacomo Rebella, Lorenza Nasone, Giacomo Boffa, Matilde Inglese
    Journal of Neurology, Neurosurgery & Psychiatry 2025
  • Lesion phenotyping based on magnetic susceptibility in pediatric multiple sclerosis
    Vincenzo Daniele Boccia, Giacomo Boffa, Caterina Lapucci, Mauro Costagli, Luca Bosisio, Maria Margherita Mancardi, Matilde Inglese, Maria Cellerino
    Journal of Neuroimaging 2024 34 5

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