Most read article(s)
- A Neuroradiologist’s Guide to Operationalizing the Response Assessment in Neuro-Oncology (RANO) Criteria Version 2.0 for Gliomas in Adults
This article is an overview of the updated version of the RANO 2.0 criteria, which are a standardized determination of radiographic response in adult gliomas on clinical trials. It provides guidance on the criteria for high- and low-grade gliomas in adults, use of the postradiotherapy MRI scan as the baseline for evaluation in newly diagnosed high-grade gliomas, the option of using volumetric tumor measurements, and the removal of subjective nonenhancing tumor evaluations in predominantly enhancing gliomas.
- Glial Fibrillary Acidic Protein Astrocytopathy: Review of Pathogenesis, Imaging Features, and Radiographic Mimics
Glial fibrillary acidic protein (GFAP) astrocytopathy is a CNS autoimmune inflammatory disorder characterized by specific antibodies targeting the intracellular filament protein in mature astrocytes. Neuroimaging findings include linear perivascular enhancement in the white matter extending in a radial pattern, periependymal enhancement, longitudinally extensive cord signal changes, intramedullary enhancement, optic neuritis, and papillitis.
- Radiologic Classification of Hippocampal Sclerosis in Epilepsy
This review explores how the International League Against Epilepsy (ILAE) subtypes of hippocampal sclerosis correlate with MRI findings. Hippocampal anatomy is reviewed in detail. The pathophysiology of hippocampal sclerosis is discussed. A radiologic classification scheme is proposed that aligns with the ILAE pathology classification, aiming to improve clinical communication and decision-making.
- Cortically Based Brain Tumors in Children: A Decision-Tree Approach in the Radiology Reading Room
This comprehensive review of cortically based brain tumors in children proposes a decision tree to help with the differential diagnosis.