Research ArticleBRAIN
Diffusion Tensor Microscopy Indicates the Cytoarchitectural Basis for Diffusion Anisotropy in the Human Hippocampus
T.M. Shepherd, E. Özarslan, A.T. Yachnis, M.A. King and S.J. Blackband
American Journal of Neuroradiology May 2007, 28 (5) 958-964;
T.M. Shepherd
E. Özarslan
A.T. Yachnis
M.A. King

References
- ↵Duvernoy HM. The Human Hippocampus. New York: Springer-Verlag;1998 :39–72
- ↵Insausti R, Amaral DG. Hippocampal formation. In: Paxinos G, Mai JK, eds. The Human Nervous System. 2nd ed. Boston: Elsevier Academic Press;2004 :871–914
- ↵Larson EB, Kukull WA, Katzman RL. Cognitive impairment: dementia and Alzheimer's disease. Annu Rev Public Health 1992;13:431–49
- ↵Van Paesschen W. Qualitative and quantitative imaging of the hippocampus in mesial temporal lobe epilepsy with hippocampal sclerosis. Neuroimaging Clin N Am 2004;14:373–400
- Sheline YI, Wang PW, Gado MH, et al. Hippocampal atrophy in recurrent major depression. Proc Natl Acad Sci U S A 1996;93:3908–13
- ↵Bigler ED, Blatter DD, Anderson CV, et al. Hippocampal volume in normal aging and traumatic brain injury. AJNR Am J Neuroradiol 1997;18:11–23
- ↵Sutula T, Cascino G, Cavazos J, et al. Mossy fiber synaptic reorganization in the epileptic human temporal lobe. Ann Neurol 1989;26:321–30
- ↵Fatterpekar GM, Naidich TP, Delman BN, et al. Cytoarchitecture of the human cerebral cortex: MR microscopy of excised specimens at 9.4 Tesla. AJNR Am J Neuroradiol 2002;23:1313–21
- ↵Chakeres DW, Whitaker CD, Dashner RA, et al. High-resolution 8 Tesla imaging of the formalin-fixed normal human hippocampus. Clin Anat 2005;18:88–91
- ↵Adachi M, Kawakatsu S, Hosoya T, et al. Morphology of the inner structure of the hippocampal formation in Alzheimer disease. AJNR Am J Neuroradiol 2003;24:1575–81
- ↵Basser PJ. Inferring microstructural features and the physiological state of tissues from diffusion-weighted images. NMR Biomed 1995;8:333–44
- ↵Basser PJ, Mattiello J, LeBihan D. Estimation of the effective self-diffusion tensor from the NMR spin echo. J Magn Reson B 1994;103:247–54
- ↵Beaulieu C. The basis of anisotropic water diffusion in the nervous system: a technical review. NMR Biomed 2002;15:435–55
- ↵Wieshmann UC, Clark CA, Symms MR, et al. Water diffusion in the human hippocampus in epilepsy. Magn Reson Imaging 1999;17:29–36
- Kalus P, Buri C, Slotboom J, et al. Volumetry and diffusion tensor imaging of hippocampal subregions in schizophrenia. Neuroreport 2004;15:867–71
- ↵Ardekani BA, Bappal A, D'Angelo D, et al. Brain morphometry using diffusion-weighted magnetic resonance imaging: application to schizophrenia. Neuroreport 2005;16:1455–59
- ↵Shepherd TM, Thelwall PE, Stanisz GJ, et al. Chemical fixation alters the water microenvironment in rat cortical brain slices: implications for MRI contrast mechanisms. Proc Intl Soc Magn Reson Med 2005;13:619
- ↵Shepherd TM, Thelwall PE, King MA, et al. Cytoarchitectural basis for water diffusion in rat hippocampal slices. Proc Intl Soc Magn Reson Med 2004;12:1231
- ↵McBain CJ, Traynelis SF, Dingledine R. Regional variation of extracellular space in the hippocampus. Science 1990;249:674–77
- ↵Wakana S, Jiang H, Nagae-Poetscher LM, et al. Fiber tract-based atlas of human white matter anatomy. Radiology 2004;230:77–87
- ↵Amaral DG, Witter MP. The three-dimensional organization of the hippocampal formation: a review of anatomical data. Neuroscience 1989;31:571–91
- ↵
- ↵Frank LR. Anisotropy in high angular resolution diffusion-weighted MRI. Magn Reson Med 2001;45:935–39
- ↵Tuch DS, Reese TG, Wiegell MR, et al. High angular resolution diffusion imaging reveals intravoxel white matter fiber heterogeneity. Magn Reson Med 2002;48:577–82
- ↵Özarslan E, Shepherd TM, Vemuri BC, et al. Resolution of complex tissue microarchitecture using the diffusion orientation transform (DOT). Neuroimage 2006;31:1086–103. Epub 2006 Mar 20
- ↵Pierpaoli C, Basser PJ. Toward a quantitative assessment of diffusion anisotropy. Magn Reson Med 1996;36:893–906
- ↵Shepherd TM, Flint J, Thelwall PE, et al. Postmortem interval alters the water relaxation and diffusion properties of nervous tissue: implications for high resolution MRI of human autopsy samples. Proc Intl Soc Magn Reson Med 2006;14:139
- ↵Seaman WJ. Postmortem Change in the Rat: A Histologic Characterization. Ames, Iowa: Iowa State University Press;1987
- ↵Burton EC, Nemetz PN. Medical error and outcomes measures: where have all the autopsies gone? MedGenMed 2000;2:E8
- ↵Sun SW, Neil JJ, Song SK. Relative indices of water diffusion anisotropy are equivalent in live and formalin-fixed mouse brains. Magn Reson Med 2003;50:743–48
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T.M. Shepherd, E. Özarslan, A.T. Yachnis, M.A. King, S.J. Blackband
Diffusion Tensor Microscopy Indicates the Cytoarchitectural Basis for Diffusion Anisotropy in the Human Hippocampus
American Journal of Neuroradiology May 2007, 28 (5) 958-964;
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