Article Figures & Data
Figures
- Fig 1.
Matrix and Matrix2 coils. The polyglycolic/polylactic acid coating of the Matrix2 coil (B), with 30% of total coil volume, was reduced from the initial Matrix (A), with 70%, to prevent miscarried elution.
Tables
Matrix2 Coil Group BPC Group P Valuea Aneurysms (patients) 121 (114) 151 (137) Age, mean ± SD (yr) 55.5 ± 11.2 57.6 ± 11.1 .136 Female, no. (%) 88 (72.7) 103 (68.2) .418 Unruptured aneurysms, no. (%) 97 (80.2) 127 (84.1) .148 Circulation, anterior:posterior, no. (%) 110:11 (90.9) 136:15 (90.1) .839 Aneurysm volume (mm3), mean ± SD 129.5 ± 268.4 95.9 ± 204.6 .243 Initial occlusion grade, complete obliteration, no. (%) 81 (66.9) 96 (63.6) .688 Initial occlusion grade, residual neck, no. (%) 33 (27.3) 48 (31.8) Initial occlusion grade, residual aneurysm, no. (%) 7 (5.8) 7 (4.6) Packing density (%), mean ± SD 32.4 ± 7.9 31.2 ± 7.3 .181 Thromboembolism, overall, no. (%) 13 (10.7) 9 (6.0) .181 Thromboembolism, symptomatic, no. (%) 1 (0.8) 2 (1.3) 1.0 Perforation or leakage, no. (%) 1 (0.8) 2 (1.3) 1.0 Coil protrusion, no. (%) 2 (1.7) 8 (5.3) .193 -
↵a P value <.05 is significant.
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- Table 2:
One-year follow-up outcomes of Matrix2 group and BPC group based on aneurysm volumes, initial occlusion grades, and packing density
Matrix2 Coil, No. (%) BPC, No. (%) P Value No. Stable Occlusion Overall Recurrence No. Stable Occlusion Overall Recurrence Major Recanalization Retreatment Major Recanalization Retreatment 21 (17.4) 11 (7.3) All aneurysm volumes 121 100 (82.6) 151 140 (92.7) .066 17 (14.0) 13 (10.7) 8 (5.3) 7 (4.6) 3 (4.5) 4 (4.4) Volume <50 mm3 67 64 (95.5) 90 86 (95.6) .404 3 (4.5) 2 (3.0) 2 (2.2) 0 (0) 9 (23.7) 1 (2.2) Volume 50–200 mm3 38 29 (76.3) 46 45 (97.8) .022a 5 (13.1) 4 (10.5) 0 (0) 0 (0) 9 (56.3) 6 (40) Volume >200 mm3 16 7 (43.8) 15 9 (60) .642 9 (56.3) 7 (43.8) 6 (40) 5 (33.3) Initial occlusion grade 9 (11.1) 4 (4.2) Complete obliteration 81 72 (88.9) 96 92 (95.8) .092 6 (7.4) 6 (7.4) 1 (1.0) 1 (1.0) 8 (24.2) 5 (10.4) Residual neck 33 25 (75.8) 48 43 (89.6) .160 7 (21.2) 5 (15.2) 5 (10.4) 5 (10.4) 4 (57.1) 2 (28.6) Residual aneurysm 7 3 (42.9) 7 5 (71.4) .558 4 (57.1) 2 (28.6) 2 (28.6) 1 (14.3) Packing density 18 (38.3) 8 (13.3) PD <30% 47 29 (61.7) 60 52 (86.7) .025a 15 (31.9) 11 (23.4) 7 (11.7) 6 (10) 2 (6.3) 1 (2) PD 30–35% 32 30 (93.7) 49 48 (98.0) .327 2 (6.3) 2 (6.3) 1 (2) 1 (2) 1 (2.4) 2 (4.8) PD >35% 42 41 (97.6) 42 40 (95.2) .557 0 (0) 0 (0) 0 (0) 0 (0) -
↵a P value <.05.
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Length of Matrix2 Coils <50% 50%–100% 100% P Valuea Aneurysm no. (%) 35 (28.9) 47 (38.8) 39 (32.2) Mean aneurysm volume (mm3) 168.5 ± 296.2 114.7 ± 237.3 112.3 ± 280.7 .597 Mean packing density (%) 30.2 ± 7.4 33.2 ± 6.4 33.5 ± 9.6 .152 Initial occlusion grade, no. (%) Complete obliteration 25 (71.4) 35 (74.4) 21 (53.8) .098 Residual neck 7 (20.0) 12 (25.5) 14 (35.9) Residual aneurysm 3 (8.6) 0 (0.0) 4 (10.3) 1-year follow-up outcomes, no. (%) Stable occlusion 25 (71.4) 42 (89.4) 33 (84.6) .209 Overall recurrence 10 (28.6) 5 (10.6) 6 (15.4) Major recanalization 8 (22.9) 5 (10.6) 4 (10.3) Retreatment 5 (14.3) 4 (8.5) 4 (10.3) -
↵a P value <.05 is significant.
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