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Research ArticleBrain
Open Access

Apolipoprotein E ε4 Does Not Modulate Amyloid-β–Associated Neurodegeneration in Preclinical Alzheimer Disease

R.S. Desikan, L.K. McEvoy, D. Holland, W.K. Thompson, J.B. Brewer, P.S. Aisen, O.A. Andreassen, B.T. Hyman, R.A. Sperling, A.M. Dale and for the Alzheimer's Disease Neuroimaging Initiative
American Journal of Neuroradiology March 2013, 34 (3) 505-510; DOI: https://doi.org/10.3174/ajnr.A3267
R.S. Desikan
aFrom the Departments of Radiology (R.S.D., L.K.E., J.B.B., A.M.D.)
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L.K. McEvoy
aFrom the Departments of Radiology (R.S.D., L.K.E., J.B.B., A.M.D.)
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D. Holland
bNeuroscience (D.H., J.B.B., P.S.A., A.M.D.)
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W.K. Thompson
cPsychiatry (W.K.T., O.A.A.), University of California, San Diego, La Jolla, California
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J.B. Brewer
aFrom the Departments of Radiology (R.S.D., L.K.E., J.B.B., A.M.D.)
bNeuroscience (D.H., J.B.B., P.S.A., A.M.D.)
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P.S. Aisen
bNeuroscience (D.H., J.B.B., P.S.A., A.M.D.)
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O.A. Andreassen
cPsychiatry (W.K.T., O.A.A.), University of California, San Diego, La Jolla, California
dInstitute of Clinical Medicine (O.A.A.), University of Oslo and Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
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B.T. Hyman
eDepartment of Neurology (B.T.H., R.A.S.), Massachusetts General Hospital, Boston, Massachusetts
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R.A. Sperling
eDepartment of Neurology (B.T.H., R.A.S.), Massachusetts General Hospital, Boston, Massachusetts
fDepartment of Neurology (R.A.S.), Brigham and Women's Hospital, Boston, Massachusetts.
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A.M. Dale
aFrom the Departments of Radiology (R.S.D., L.K.E., J.B.B., A.M.D.)
bNeuroscience (D.H., J.B.B., P.S.A., A.M.D.)
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American Journal of Neuroradiology: 34 (3)
American Journal of Neuroradiology
Vol. 34, Issue 3
1 Mar 2013
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Cite this article
R.S. Desikan, L.K. McEvoy, D. Holland, W.K. Thompson, J.B. Brewer, P.S. Aisen, O.A. Andreassen, B.T. Hyman, R.A. Sperling, A.M. Dale, for the Alzheimer's Disease Neuroimaging Initiative
Apolipoprotein E ε4 Does Not Modulate Amyloid-β–Associated Neurodegeneration in Preclinical Alzheimer Disease
American Journal of Neuroradiology Mar 2013, 34 (3) 505-510; DOI: 10.3174/ajnr.A3267

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Apolipoprotein E ε4 Does Not Modulate Amyloid-β–Associated Neurodegeneration in Preclinical Alzheimer Disease
R.S. Desikan, L.K. McEvoy, D. Holland, W.K. Thompson, J.B. Brewer, P.S. Aisen, O.A. Andreassen, B.T. Hyman, R.A. Sperling, A.M. Dale, for the Alzheimer's Disease Neuroimaging Initiative
American Journal of Neuroradiology Mar 2013, 34 (3) 505-510; DOI: 10.3174/ajnr.A3267
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    Stephanie JB Vos, Chengjie Xiong, Pieter Jelle Visser, Mateusz S Jasielec, Jason Hassenstab, Elizabeth A Grant, Nigel J Cairns, John C Morris, David M Holtzman, Anne M Fagan
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    R S Desikan, A J Schork, Y Wang, A Witoelar, M Sharma, L K McEvoy, D Holland, J B Brewer, C-H Chen, W K Thompson, D Harold, J Williams, M J Owen, M C O'Donovan, M A Pericak-Vance, R Mayeux, J L Haines, L A Farrer, G D Schellenberg, P Heutink, A B Singleton, A Brice, N W Wood, J Hardy, M Martinez, S H Choi, A DeStefano, M A Ikram, J C Bis, A Smith, A L Fitzpatrick, L Launer, C van Duijn, S Seshadri, I D Ulstein, D Aarsland, T Fladby, S Djurovic, B T Hyman, J Snaedal, H Stefansson, K Stefansson, T Gasser, O A Andreassen, A M Dale
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    Frontiers in Aging Neuroscience 2014 6
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    Molecular Neurodegeneration 2013 8 1
  • Nonlinear cerebral atrophy patterns across the Alzheimer's disease continuum: impact of APOE4 genotype
    J.D. Gispert, L. Rami, G. Sánchez-Benavides, C. Falcon, A. Tucholka, S. Rojas, J.L. Molinuevo
    Neurobiology of Aging 2015 36 10
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    Revue Neurologique 2013 169 10
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