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Research ArticleBrain
Open Access

A Novel Technique for the Measurement of CBF and CBV with Robot-Arm-Mounted Flat Panel CT in a Large-Animal Model

O. Beuing, A. Boese, Y. Kyriakou, Y. Deuerling-Zengh, B. Jöllenbeck, C. Scherlach, A. Lenz, S. Serowy, S. Gugel, G. Rose and M. Skalej
American Journal of Neuroradiology September 2014, 35 (9) 1740-1745; DOI: https://doi.org/10.3174/ajnr.A3973
O. Beuing
aFrom the Institute of Neuroradiology (O.B., C.S., A.L., S.S., M.S.)
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A. Boese
cHealthcare Telematics and Medical Engineering (A.B., S.G., G.R.), Otto von Guericke University, Magdeburg, Germany
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Y. Kyriakou
dSiemens AG (Y.K., Y.D.-Z.), Healthcare Sector, Erlangen, Germany.
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Y. Deuerling-Zengh
dSiemens AG (Y.K., Y.D.-Z.), Healthcare Sector, Erlangen, Germany.
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B. Jöllenbeck
bDepartment of Neurosurgery (B.J.)
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C. Scherlach
aFrom the Institute of Neuroradiology (O.B., C.S., A.L., S.S., M.S.)
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A. Lenz
aFrom the Institute of Neuroradiology (O.B., C.S., A.L., S.S., M.S.)
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S. Serowy
aFrom the Institute of Neuroradiology (O.B., C.S., A.L., S.S., M.S.)
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S. Gugel
cHealthcare Telematics and Medical Engineering (A.B., S.G., G.R.), Otto von Guericke University, Magdeburg, Germany
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G. Rose
cHealthcare Telematics and Medical Engineering (A.B., S.G., G.R.), Otto von Guericke University, Magdeburg, Germany
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M. Skalej
aFrom the Institute of Neuroradiology (O.B., C.S., A.L., S.S., M.S.)
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REFERENCES

  1. 1.↵
    Tissue plasminogen activator for acute ischemic stroke: the National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. N Engl J Med 1995;333:1581–87
    CrossRefPubMedWeb of Science
  2. 2.↵
    1. Lees KR,
    2. Bluhmki E,
    3. von Kummer R,
    4. et al
    . Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials. Lancet 2010;375:1695–703
    CrossRefPubMedWeb of Science
  3. 3.↵
    1. Sandercock P,
    2. Wardlaw JM,
    3. Lindley RI,
    4. et al
    . The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third International Stroke Trial [IST-3]): a randomised controlled trial. Lancet 2012;379:2352–63
    CrossRefPubMedWeb of Science
  4. 4.↵
    1. Mattle HP,
    2. Arnold M,
    3. Georgiadis D,
    4. et al
    . Comparison of intraarterial and intravenous thrombolysis for ischemic stroke with hyperdense middle cerebral artery sign. Stroke 2008;39:379–83
    Abstract/FREE Full Text
  5. 5.↵
    Penumbra Pivotal Stroke Trial Investigators. The Penumbra Pivotal Stroke Trial: safety and effectiveness of a new generation of mechanical devices for clot removal in intracranial large vessel occlusive disease. Stroke 2009;40:2761–68
    Abstract/FREE Full Text
  6. 6.↵
    1. Dávalos A,
    2. Pereira VM,
    3. Chapot R,
    4. et al
    . Retrospective multicenter study of Solitaire FR for revascularization in the treatment of acute ischemic stroke. Stroke 2012;43:2699–705
    Abstract/FREE Full Text
  7. 7.↵
    1. Nogueira RG,
    2. Lutsep HL,
    3. Gupta R,
    4. et al
    . Trevo versus Merci retrievers for thrombectomy revascularisation of large vessel occlusions in acute ischaemic stroke (TREVO 2): a randomised trial. Lancet 2012;380:1231–40
    CrossRefPubMedWeb of Science
  8. 8.↵
    1. Saver JL,
    2. Jahan R,
    3. Levy EI,
    4. et al
    . Solitaire flow restoration device versus the Merci retriever in patients with acute ischaemic stroke (SWIFT): a randomised, parallel-group, non-inferiority trial. Lancet 2012;380:1241–49
    CrossRefPubMedWeb of Science
  9. 9.↵
    1. Lev MH
    . Perfusion imaging of acute stroke: its role in current and future clinical practice. Radiology 2013;266:22–27
    CrossRefPubMedWeb of Science
  10. 10.↵
    1. Struffert T,
    2. Deuerling-Zheng Y,
    3. Engelhorn T,
    4. et al
    . Feasibility of cerebral blood volume mapping by flat panel detector CT in the angiography suite: first experience in patients with acute middle cerebral artery occlusions. AJNR Am J Neuroradiol 2012;33:618–25
    Abstract/FREE Full Text
  11. 11.↵
    1. Struffert T,
    2. Deuerling-Zheng Y,
    3. Kloska S,
    4. et al
    . Cerebral blood volume imaging by flat detector computed tomography in comparison to conventional multislice perfusion CT. Eur Radiol 2011;21:882–89
    CrossRefPubMed
  12. 12.↵
    1. Bley T,
    2. Strother CM,
    3. Pulfer K,
    4. et al
    . C-arm CT measurement of cerebral blood volume in ischemic stroke: an experimental study in canines. AJNR Am J Neuroradiol 2010;31:536–40
    Abstract/FREE Full Text
  13. 13.↵
    1. Ganguly A,
    2. Fieselmann A,
    3. Marks M,
    4. et al
    . Cerebral CT perfusion using an interventional C-arm imaging system: cerebral blood flow measurements. AJNR Am J Neuroradiol 2011;32:1525–31
    Abstract/FREE Full Text
  14. 14.↵
    1. Royalty K,
    2. Manhart M,
    3. Pulfer K,
    4. et al
    . C-arm CT measurement of cerebral blood volume and cerebral blood flow using a novel high-speed acquisition and a single intravenous contrast injection. AJNR Am J Neuroradiol 2013;34:2131–38
    Abstract/FREE Full Text
  15. 15.↵
    1. Boltze J,
    2. Forschler A,
    3. Nitzsche B,
    4. et al
    . Permanent middle cerebral artery occlusion in sheep: a novel large animal model of focal cerebral ischemia. J Cereb Blood Flow Metab 2008;28:1951–64
    CrossRefPubMedWeb of Science
  16. 16.↵
    1. Fieselmann A,
    2. Dennerlein F,
    3. Deuerling-Zheng Y,
    4. et al
    . A model for filtered backprojection reconstruction artifacts due to time-varying attenuation values in perfusion C-arm CT. Phys Med Biol 2011;56:3701–17
    PubMed
  17. 17.↵
    1. Landis JR,
    2. Koch GG
    . The measurement of observer agreement for categorical data. Biometrics 1977;33:159–74
    CrossRefPubMedWeb of Science
  18. 18.↵
    1. Abou-Chebl A
    . Endovascular treatment of acute ischemic stroke may be safely performed with no time window limit in appropriately selected patients. Stroke 2010;41:1996–2000
    Abstract/FREE Full Text
  19. 19.↵
    1. Turk A,
    2. Magarik JA,
    3. Chaudry I,
    4. et al
    . CT perfusion-guided patient selection for endovascular treatment of acute ischemic stroke is safe and effective. J Neurointerv Surg 2012;4:261–65
    Abstract/FREE Full Text
  20. 20.↵
    1. Bivard A,
    2. McElduff P,
    3. Spratt N,
    4. et al
    . Defining the extent of irreversible brain ischemia using perfusion computed tomography. Cerebrovasc Dis 2011;31:238–45
    CrossRefPubMed
  21. 21.↵
    1. Davis S,
    2. Campbell B,
    3. Christensen S,
    4. et al
    . Perfusion/diffusion mismatch is valid and should be used for selecting delayed interventions. Transl Stroke Res 2012;3:188–97
    PubMed
  22. 22.↵
    1. Kamalian S,
    2. Maas MB,
    3. Goldmacher GV,
    4. et al
    . CT cerebral blood flow maps optimally correlate with admission diffusion-weighted imaging in acute stroke but thresholds vary by postprocessing platform. Stroke 2011;42:1923–28
    Abstract/FREE Full Text
  23. 23.↵
    1. Struffert T,
    2. Eyupoglu IY,
    3. Huttner HB,
    4. et al
    . Clinical evaluation of flat-panel detector compared with multislice computed tomography in 65 patients with acute intracranial hemorrhage: initial results: clinical article. J Neurosurg 2010;113:901–07
    CrossRefPubMedWeb of Science
  24. 24.↵
    1. Blanc R,
    2. Pistocchi S,
    3. Babic D,
    4. et al
    . Intravenous flat-detector CT angiography in acute ischemic stroke management. Neuroradiology 2012;54:383–91
    CrossRefPubMedWeb of Science
  25. 25.↵
    1. Jeon JS,
    2. Sheen SH,
    3. Hwang GJ,
    4. et al
    . Feasibility of intravenous flat panel detector CT angiography for intracranial arterial stenosis. AJNR Am J Neuroradiol 2013;34:129–34
    Abstract/FREE Full Text
  26. 26.↵
    1. Doelken M,
    2. Struffert T,
    3. Richter G,
    4. et al
    . Flat-panel detector volumetric CT for visualization of subarachnoid hemorrhage and ventricles: preliminary results compared to conventional CT. Neuroradiology 2008;50:517–23
    CrossRefPubMedWeb of Science
  27. 27.↵
    1. Konstas AA,
    2. Goldmakher GV,
    3. Lee TY,
    4. et al
    . Theoretic basis and technical implementations of CT perfusion in acute ischemic stroke. Part 1. Theoretic basis. AJNR Am J Neuroradiol 2009;30:662–68
    Abstract/FREE Full Text
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American Journal of Neuroradiology: 35 (9)
American Journal of Neuroradiology
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Cite this article
O. Beuing, A. Boese, Y. Kyriakou, Y. Deuerling-Zengh, B. Jöllenbeck, C. Scherlach, A. Lenz, S. Serowy, S. Gugel, G. Rose, M. Skalej
A Novel Technique for the Measurement of CBF and CBV with Robot-Arm-Mounted Flat Panel CT in a Large-Animal Model
American Journal of Neuroradiology Sep 2014, 35 (9) 1740-1745; DOI: 10.3174/ajnr.A3973

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A Novel Technique for the Measurement of CBF and CBV with Robot-Arm-Mounted Flat Panel CT in a Large-Animal Model
O. Beuing, A. Boese, Y. Kyriakou, Y. Deuerling-Zengh, B. Jöllenbeck, C. Scherlach, A. Lenz, S. Serowy, S. Gugel, G. Rose, M. Skalej
American Journal of Neuroradiology Sep 2014, 35 (9) 1740-1745; DOI: 10.3174/ajnr.A3973
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