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COVID-19-Associated Acute Disseminated Encephalomyelitis–Like Disease

F.B. Assunção, D.C. Fragoso, T.L.P. Donoso Scoppetta and A.C. Martins Maia
American Journal of Neuroradiology April 2021, 42 (4) E21-E23; DOI: https://doi.org/10.3174/ajnr.A6967
F.B. Assunção
aDivision of NeuroradiologySanta Casa de Misericórdia de São PauloSão Paulo-SP, Brazil
bDivision of NeuroradiologyRede de Hospitais São Camilo de São PauloSão Paulo-SP, Brazil
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D.C. Fragoso
cDivision of NeuroradiologySanta Casa de Misericórdia de São PauloSão Paulo-SP, Brazil
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T.L.P. Donoso Scoppetta
dDivision of NeuroradiologySanta Casa de Misericórdia de São PauloSão Paulo-SP, Brazil
eDivision of NeuroradiologyRede de Hospitais São Camilo de São PauloSão Paulo-SP, Brazil
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A.C. Martins Maia
fDivision of NeuroradiologySanta Casa de Misericórdia de São PauloSão Paulo-SP, Brazil
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    FIG 1.

    FLAIR images (A–C) depict multiple nodular/oval hyperintensities that involve the deep and periventricular cerebral white matter, splenium of the corpus callosum, and pons. All lesions show restricted diffusion on DWI sequences (D–F). Neither gadolinium enhancement (G–I) nor hemorrhages (not shown) were demonstrated.

  • FIG 2.
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    FIG 2.

    Axial T2WI (A–C) demonstrates multiple large hyperintense oval lesions predominantly affecting the subcortical WM of the cerebral hemispheres, the posterior arm of the right internal capsule, and the infratentorial fossa structures, particularly in the middle cerebellar peduncles. All lesions concurrently demonstrate diffusion restriction observed in the diffusion sequence (D–F) and gadolinium enhancement in the postcontrast T1 sequence (G–I). Most lesions have an open-ring enhancement pattern, best characterized in the right middle cerebellar peduncle (arrowhead in I).

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American Journal of Neuroradiology: 42 (4)
American Journal of Neuroradiology
Vol. 42, Issue 4
1 Apr 2021
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Cite this article
F.B. Assunção, D.C. Fragoso, T.L.P. Donoso Scoppetta, A.C. Martins Maia
COVID-19-Associated Acute Disseminated Encephalomyelitis–Like Disease
American Journal of Neuroradiology Apr 2021, 42 (4) E21-E23; DOI: 10.3174/ajnr.A6967

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COVID-19-Associated Acute Disseminated Encephalomyelitis–Like Disease
F.B. Assunção, D.C. Fragoso, T.L.P. Donoso Scoppetta, A.C. Martins Maia
American Journal of Neuroradiology Apr 2021, 42 (4) E21-E23; DOI: 10.3174/ajnr.A6967
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