Case of the Week
Section Editors: Matylda Machnowska1 and Anvita Pauranik2
1University of Toronto, Toronto, Ontario, Canada
2BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada
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January 2, 2014
Granular Cell Tumor
- Also known as choristoma and infundibuloma
- Rare, benign, slow-growing tumor arising from the distribution of the neurohypophysis
- Clinical Presentation: Visual disturbance, headaches or amenorrhea, may also be asymptomatic. Rarely present with diabetes insipidus, galactorrhea, or prolactinemia.
- Key Diagnostic Features: Well-defined suprasellar or mixed intra/suprasellar mass. There are no documented cases of purely intrasellar masses. Solid components are isointense to brain on T1 and T2, with heterogeneous or homogeneous postcontrast enhancement. The mass tends to be hyperdense on CT.
- DDx: Neoplastic considerations include germinoma, infundibular adenoma, metastasis, and Langerhans cell histiocytosis. Inflammatory lesions in the differential could include sarcoidosis or lymphocytic hypophysitis.
- Rx: Resection
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