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Research ArticlePediatrics
Open Access

White Matter Impairment in Rett Syndrome: Diffusion Tensor Imaging Study with Clinical Correlations

A. Mahmood, G. Bibat, A.-L. Zhan, I. Izbudak, L. Farage, A. Horska, S. Mori and S. Naidu
American Journal of Neuroradiology February 2010, 31 (2) 295-299; DOI: https://doi.org/10.3174/ajnr.A1792
A. Mahmood
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G. Bibat
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A.-L. Zhan
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I. Izbudak
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L. Farage
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A. Horska
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S. Mori
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S. Naidu
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Article Figures & Data

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    Fig 1.

    Total of 42 ROIs (21 in each hemisphere) and 3 in the corpus callosum are shown.

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    Fig 2.

    Comparison of FA among patients categorized by speech capacity in the superior longitudinal fasciculus and control subjects.

Tables

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  • Comparisons of FA between patients with RTT and control subjects

    ROISideRTTControlP value
    GC0.555 (0.052)0.67 (0.033).0001
    SCC0.56 (0.08)0.682 (0.04).0001
    CC0.419 (0.046)0.498 (0.056).0001
    ECR0.291 (0.059)0.321 (0.037).008
    L0.296 (0.042)0.337 (0.038).0001
    IFO1R0.37 (0.051)0.444 (0.044).0001
    L0.374 (0.051)0.427 (0.045).0001
    IFO2R0.338 (0.039)0.392 (0.051).0001
    L0.341 (0.034)0.384 (0.057).0018
    SSR0.403 (0.047)0.433 (0.043).034
    L0.392 (0.044)0.435 (0.046).001
    SLFR0.338 (0.062)0.369 (0.049).056
    L0.34 (0.055)0.402 (0.052).0001
    PCRR0.413 (0.042)0.383 (0.049).018
    L0.413 (0.044)0.387 (0.055).052
    ALICR0.481 (0.043)0.478 (0.052)> .99
    L0.473 (0.049)0.482 (0.046).92
    PLICR0.547 (0.033)0.565 (0.024).02
    L0.548 (0.037)0.566 (0.029).16
    ALIC2R0.475 (0.051)0.509 (0.042).012
    L0.463 (0.047)0.51 (0.042).0001
    PTR1R0.428 (0.046)0.455 (0.04).018
    L0.424 (0.051)0.439 (0.045).346
    PTR2R0.46 (0.032)0.474 (0.032).18
    L0.462 (0.037)0.479 (0.038).12
    FW1R0.356 (0.059)0.394 (0.052).014
    L0.352 (0.046)0.401 (0.051).0001
    FW2R0.356 (0.038)0.345 (0.043).54
    L0.367 (0.048)0.361 (0.041)> .99
    FW3R0.394 (0.047)0.455 (0.05).0001
    L0.388 (0.048)0.457 (0.049).0001
    CPR0.552 (0.06)0.557 (0.058)> .99
    L0.525 (0.06)0.544 (0.047).4
    SCPR0.542 (0.098)0.567 (0.084).7
    L0.537 (0.091)0.568 (0.099).684
    MCPR0.518 (0.053)0.55 (0.046).078
    L0.531 (0.059)0.535 (0.057).914
    CG1R0.275 (0.056)0.336 (0.045).0001
    L0.298 (0.053)0.377 (0.05).0001
    CG2R0.301 (0.059)0.31 (0.055)> .99
    L0.281 (0.038)0.301 (0.056).25
    CG3R0.294 (0.05)0.307 (0.061).9
    L0.278 (0.035)0.296 (0.058).228
    CG4R0.296 (0.05)0.321 (0.049).16
    L0.298 (0.061)0.302 (0.049)> .99
    FX/STR0.413 (0.087)0.426 (0.065)> .99
    L0.418 (0.074)0.442 (0.063).334
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American Journal of Neuroradiology: 31 (2)
American Journal of Neuroradiology
Vol. 31, Issue 2
1 Feb 2010
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A. Mahmood, G. Bibat, A.-L. Zhan, I. Izbudak, L. Farage, A. Horska, S. Mori, S. Naidu
White Matter Impairment in Rett Syndrome: Diffusion Tensor Imaging Study with Clinical Correlations
American Journal of Neuroradiology Feb 2010, 31 (2) 295-299; DOI: 10.3174/ajnr.A1792

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White Matter Impairment in Rett Syndrome: Diffusion Tensor Imaging Study with Clinical Correlations
A. Mahmood, G. Bibat, A.-L. Zhan, I. Izbudak, L. Farage, A. Horska, S. Mori, S. Naidu
American Journal of Neuroradiology Feb 2010, 31 (2) 295-299; DOI: 10.3174/ajnr.A1792
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