Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Other Publications
    • ajnr

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

Welcome to the new AJNR, Updated Hall of Fame, and more. Read the full announcements.


AJNR is seeking candidates for the position of Associate Section Editor, AJNR Case Collection. Read the full announcement.

 

Getting new auth cookie, if you see this message a lot, tell someone!
Research ArticleInterventional

Geometric and Compositional Appearance of Atheroma in an Angiographically Normal Carotid Artery in Patients with Atherosclerosis

L. Dong, H.R. Underhill, W. Yu, H. Ota, T.S. Hatsukami, T.L. Gao, Z. Zhang, M. Oikawa, X. Zhao and C. Yuan
American Journal of Neuroradiology February 2010, 31 (2) 311-316; DOI: https://doi.org/10.3174/ajnr.A1793
L. Dong
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
H.R. Underhill
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
W. Yu
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
H. Ota
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
T.S. Hatsukami
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
T.L. Gao
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Z. Zhang
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. Oikawa
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
X. Zhao
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
C. Yuan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Moore WS,
    2. Barnett HJ,
    3. Beebe HG,
    4. et al
    . Guidelines for carotid endarterectomy: a multidisciplinary consensus statement from the Ad Hoc Committee, American Heart Association. Circulation 1995;91:566–79
    Abstract/FREE Full Text
  2. 2.↵
    Endarterectomy for moderate symptomatic carotid stenosis: interim results from the MRC European Carotid Surgery Trial. Lancet 1996;347:1591–93
    PubMedWeb of Science
  3. 3.↵
    Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis: North American Symptomatic Carotid Endarterectomy Trial Collaborators. N Engl J Med 1991;325:445–53
    CrossRefPubMedWeb of Science
  4. 4.↵
    Clinical alert: benefit of carotid endarterectomy for patients with high-grade stenosis of the internal carotid artery—National Institute of Neurological Disorders and Stroke and Trauma Division. North American Symptomatic Carotid Endarterectomy Trial (NASCET) investigators. Stroke 1991;22:816–17
    FREE Full Text
  5. 5.↵
    1. Rothwell PM,
    2. Slattery J,
    3. Warlow CP
    . A systematic comparison of the risks of stroke and death due to carotid endarterectomy for symptomatic and asymptomatic stenosis. Stroke 1996;27:266–69
    Abstract/FREE Full Text
  6. 6.↵
    1. Rothwell PM,
    2. Gutnikov SA,
    3. Warlow CP
    . Reanalysis of the final results of the European Carotid Surgery Trial. Stroke 2003;34:514–23
    Abstract/FREE Full Text
  7. 7.↵
    1. Babiarz LS,
    2. Astor B,
    3. Mohamed MA,
    4. et al
    . Comparison of gadolinium-enhanced cardiovascular magnetic resonance angiography with high-resolution black blood cardiovascular magnetic resonance for assessing carotid artery stenosis. J Cardiovasc Magn Reson 2007;9:63–70
    CrossRefPubMed
  8. 8.↵
    1. Saam T,
    2. Underhill HR,
    3. Chu B,
    4. et al
    . Prevalence of American Heart Association type VI carotid atherosclerotic lesions identified by magnetic resonance imaging for different levels of stenosis as measured by duplex ultrasound. J Am Coll Cardiol 2008;51:1014–21
    CrossRefPubMedWeb of Science
  9. 9.↵
    1. Yuan C,
    2. Kerwin WS,
    3. Yarnykh VL,
    4. et al
    . MRI of atherosclerosis in clinical trials. NMR Biomed 2006;19:636–54
    CrossRefPubMedWeb of Science
  10. 10.↵
    1. Underhill HR,
    2. Yarnykh VL,
    3. Hatsukami TS,
    4. et al
    . Carotid plaque morphology and composition: initial comparison between 1.5- and 3.0-T magnetic field strengths. Radiology 2008;248:550–60
    CrossRefPubMed
  11. 11.↵
    1. Yarnykh VL,
    2. Yuan C
    . T1-insensitive flow suppression using quadruple inversion-recovery. Magn Reson Med 2002;48:899–905
    CrossRefPubMedWeb of Science
  12. 12.↵
    1. Yarnykh VL,
    2. Yuan C
    . Multislice double inversion-recovery black-blood imaging with simultaneous slice reinversion. J Magn Reson Imaging 2003;17:478–83
    CrossRefPubMed
  13. 13.↵
    1. Kerwin W,
    2. Xu D,
    3. Liu F,
    4. et al
    . Magnetic resonance imaging of carotid atherosclerosis: plaque analysis. Top Magn Reson Imaging 2007;18:371–78
    PubMed
  14. 14.↵
    1. Nissen SE,
    2. Tuzcu EM,
    3. Schoenhagen P,
    4. et al
    . Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: a randomized controlled trial. JAMA 2004;291:1071–80
    CrossRefPubMedWeb of Science
  15. 15.↵
    1. Saam T,
    2. Ferguson MS,
    3. Yarnykh VL,
    4. et al
    . Quantitative evaluation of carotid plaque composition by in vivo MRI. Arterioscler Thromb Vasc Biol 2005;25:234–39
    Abstract/FREE Full Text
  16. 16.↵
    1. Hatsukami TS,
    2. Ross R,
    3. Polissar NL,
    4. et al
    . Visualization of fibrous cap thickness and rupture in human atherosclerotic carotid plaque in vivo with high-resolution magnetic resonance imaging. Circulation 2000;102:959–64
    Abstract/FREE Full Text
  17. 17.↵
    1. Cai J,
    2. Hatsukami TS,
    3. Ferguson MS,
    4. et al
    . In vivo quantitative measurement of intact fibrous cap and lipid-rich necrotic core size in atherosclerotic carotid plaque: comparison of high-resolution, contrast-enhanced magnetic resonance imaging and histology. Circulation 2005;112:3437–44
    Abstract/FREE Full Text
  18. 18.↵
    1. Glagov S,
    2. Weisenberg E,
    3. Zarins CK,
    4. et al
    . Compensatory enlargement of human atherosclerotic coronary arteries. N Engl J Med 1987;316:1371–75
    CrossRefPubMedWeb of Science
  19. 19.↵
    1. Rothwell PM,
    2. Gibson RJ,
    3. Slattery J,
    4. et al
    . Equivalence of measurements of carotid stenosis: a comparison of three methods on 1001 angiograms—European Carotid Surgery Trialists' Collaborative Group. Stroke 1994;25:2435–39
    Abstract/FREE Full Text
  20. 20.↵
    1. Griffiths GD,
    2. Razzaq R,
    3. Farrell A,
    4. et al
    . Variability in measurement of internal carotid artery stenosis by arch angiography and duplex ultrasonography: time for a reappraisal? Eur J Vasc Endovasc Surg 2001;21:130–36
    CrossRefPubMed
  21. 21.↵
    1. Falk E
    . Why do plaques rupture? Circulation 1992;86:III30–42
    PubMed
  22. 22.↵
    1. Virmani R,
    2. Burke AP,
    3. Farb A,
    4. et al
    . Pathology of the vulnerable plaque. J Am Coll Cardiol 2006;47:C13–18
    CrossRefPubMedWeb of Science
  23. 23.↵
    1. Kolodgie FD,
    2. Gold HK,
    3. Burke AP,
    4. et al
    . Intraplaque hemorrhage and progression of coronary atheroma. N Engl J Med 2003;349:2316–25
    CrossRefPubMedWeb of Science
  24. 24.↵
    1. Yuan C,
    2. Zhang SX,
    3. Polissar NL,
    4. et al
    . Identification of fibrous cap rupture with magnetic resonance imaging is highly associated with recent transient ischemic attack or stroke. Circulation 2002;105:181–85
    Abstract/FREE Full Text
  25. 25.↵
    1. Murphy RE,
    2. Moody AR,
    3. Morgan PS,
    4. et al
    . Prevalence of complicated carotid atheroma as detected by magnetic resonance direct thrombus imaging in patients with suspected carotid artery stenosis and previous acute cerebral ischemia. Circulation 2003;107:3053–58
    Abstract/FREE Full Text
  26. 26.↵
    1. Takaya N,
    2. Yuan C,
    3. Chu B,
    4. et al
    . Presence of intraplaque hemorrhage stimulates progression of carotid atherosclerotic plaques: a high-resolution magnetic resonance imaging study. Circulation 2005;111:2768–75
    Abstract/FREE Full Text
  27. 27.↵
    1. Takaya N,
    2. Yuan C,
    3. Chu B,
    4. et al
    . Association between carotid plaque characteristics and subsequent ischemic cerebrovascular events: a prospective assessment with MRI—initial results. Stroke 2006;37:818–23
    Abstract/FREE Full Text
  28. 28.↵
    1. Sacco RL,
    2. Ellenberg JH,
    3. Mohr JP,
    4. et al
    . Infarcts of undetermined cause: the NINCDS Stroke Data Bank. Ann Neurol 1989;25:382–90
    CrossRefPubMedWeb of Science
  29. 29.↵
    1. Kizer JR
    . Evaluation of the patient with unexplained stroke. Coron Artery Dis 2008;19:535–40
    CrossRefPubMed
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 31 (2)
American Journal of Neuroradiology
Vol. 31, Issue 2
1 Feb 2010
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Geometric and Compositional Appearance of Atheroma in an Angiographically Normal Carotid Artery in Patients with Atherosclerosis
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
L. Dong, H.R. Underhill, W. Yu, H. Ota, T.S. Hatsukami, T.L. Gao, Z. Zhang, M. Oikawa, X. Zhao, C. Yuan
Geometric and Compositional Appearance of Atheroma in an Angiographically Normal Carotid Artery in Patients with Atherosclerosis
American Journal of Neuroradiology Feb 2010, 31 (2) 311-316; DOI: 10.3174/ajnr.A1793

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Geometric and Compositional Appearance of Atheroma in an Angiographically Normal Carotid Artery in Patients with Atherosclerosis
L. Dong, H.R. Underhill, W. Yu, H. Ota, T.S. Hatsukami, T.L. Gao, Z. Zhang, M. Oikawa, X. Zhao, C. Yuan
American Journal of Neuroradiology Feb 2010, 31 (2) 311-316; DOI: 10.3174/ajnr.A1793
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • Abbreviations
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Chinese Atherosclerosis Risk Evaluation (CARE II) study: a novel cross-sectional, multicentre study of the prevalence of high-risk atherosclerotic carotid plaque in Chinese patients with ischaemic cerebrovascular events--design and rationale
  • Prediction of High-Risk Plaque Development and Plaque Progression With the Carotid Atherosclerosis Score
  • Sustained Acceleration in Carotid Atherosclerotic Plaque Progression With Intraplaque Hemorrhage: A Long-Term Time Course Study
  • What Will Noninvasive Carotid Atherosclerosis Imaging Show Us About High-Risk Coronary Plaques?
  • Discriminating Carotid Atherosclerotic Lesion Severity by Luminal Stenosis and Plaque Burden: A Comparison Utilizing High-Resolution Magnetic Resonance Imaging at 3.0 Tesla
  • A Noninvasive Imaging Approach to Assess Plaque Severity: The Carotid Atherosclerosis Score
  • Crossref (42)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • MRI of carotid atherosclerosis: clinical implications and future directions
    Hunter R. Underhill, Thomas S. Hatsukami, Zahi A. Fayad, Valentin Fuster, Chun Yuan
    Nature Reviews Cardiology 2010 7 3
  • Sustained Acceleration in Carotid Atherosclerotic Plaque Progression With Intraplaque Hemorrhage
    Jie Sun, Hunter R. Underhill, Daniel S. Hippe, Yunjing Xue, Chun Yuan, Thomas S. Hatsukami
    JACC: Cardiovascular Imaging 2012 5 8
  • Discriminating Carotid Atherosclerotic Lesion Severity by Luminal Stenosis and Plaque Burden
    Xihai Zhao, Hunter R. Underhill, Qian Zhao, Jianming Cai, Feiyu Li, Minako Oikawa, Li Dong, Hideki Ota, Thomas S. Hatsukami, Baocheng Chu, Chun Yuan
    Stroke 2011 42 2
  • Association of carotid atherosclerotic plaque features with acute ischemic stroke: A magnetic resonance imaging study
    Huilin Zhao, Xihai Zhao, Xiaosheng Liu, Ye Cao, Daniel S. Hippe, Jie Sun, Feiyu Li, Jianrong Xu, Chun Yuan
    European Journal of Radiology 2013 82 9
  • Ultrasound-Based Carotid Elastography for Detection of Vulnerable Atherosclerotic Plaques Validated by Magnetic Resonance Imaging
    Chengwu Huang, Xiaochang Pan, Qiong He, Manwei Huang, Lingyun Huang, Xihai Zhao, Chun Yuan, Jing Bai, Jianwen Luo
    Ultrasound in Medicine & Biology 2016 42 2
  • Prediction of High-Risk Plaque Development and Plaque Progression With the Carotid Atherosclerosis Score
    Dongxiang Xu, Daniel S. Hippe, Hunter R. Underhill, Minako Oikawa-Wakayama, Li Dong, Kiyofumi Yamada, Chun Yuan, Thomas S. Hatsukami
    JACC: Cardiovascular Imaging 2014 7 4
  • Chinese Atherosclerosis Risk Evaluation (CARE II) study: a novel cross-sectional, multicentre study of the prevalence of high-risk atherosclerotic carotid plaque in Chinese patients with ischaemic cerebrovascular events—design and rationale
    Xihai Zhao, Rui Li, Daniel S Hippe, Thomas S Hatsukami, Chun Yuan
    Stroke and Vascular Neurology 2017 2 1
  • A Noninvasive Imaging Approach to Assess Plaque Severity: The Carotid Atherosclerosis Score
    H.R. Underhill, T.S. Hatsukami, J. Cai, W. Yu, J.K. DeMarco, N.L. Polissar, H. Ota, X. Zhao, L. Dong, M. Oikawa, C. Yuan
    American Journal of Neuroradiology 2010 31 6
  • Late Stage Complicated Atheroma in Low-Grade Stenotic Carotid Disease: MR Imaging Depiction—Prevalence and Risk Factors
    Helen M. C. Cheung, Alan R. Moody, Navneet Singh, Richard Bitar, James Zhan, General Leung
    Radiology 2011 260 3
  • Clinical Factors Associated With High-Risk Carotid Plaque Features as Assessed by Magnetic Resonance Imaging in Patients With Established Vascular Disease (from the AIM-HIGH Study)
    Xue-Qiao Zhao, Thomas S. Hatsukami, Daniel S. Hippe, Jie Sun, Niranjan Balu, Daniel A. Isquith, John R. Crouse, Todd Anderson, John Huston, Nayak Polissar, Kevin O'Brien, Chun Yuan
    The American Journal of Cardiology 2014 114 9

More in this TOC Section

  • SAVE vs. Solumbra Techniques for Thrombectomy
  • CT Perfusion&Reperfusion in Acute Ischemic Stroke
  • Delayed Reperfusion Post-Thrombectomy&Thrombolysis
Show more Interventional

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editors Choice
  • Fellow Journal Club
  • Letters to the Editor

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

Special Collections

  • Special Collections

Resources

  • News and Updates
  • Turn around Times
  • Submit a Manuscript
  • Author Policies
  • Manuscript Submission Guidelines
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Submit a Case
  • Become a Reviewer/Academy of Reviewers
  • Get Peer Review Credit from Publons

Multimedia

  • AJNR Podcast
  • AJNR SCANtastic
  • Video Articles

About Us

  • About AJNR
  • Editorial Board
  • Not an AJNR Subscriber? Join Now
  • Alerts
  • Feedback
  • Advertise with us
  • Librarian Resources
  • Permissions
  • Terms and Conditions

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire