Clinical Application of Arterial Spin-Labeling MR Imaging in Patients with Carotid Stenosis: Quantitative Comparative Study with Single-Photon Emission CT

CBF assessments by ASL and SPECT in the region of interest analysis. A, Resting CBF values measured by ASL are plotted against the corresponding CBF values measured by SPECT from bilateral frontal and temporal ROIs. The solid line shows the line of equality. B, Bland-Altman plot of CBF values measured by ASL and SPECT. A plot of the differences between the methods against their means is shown. The broken line shows average of differences, and the solid line indicates ±1.96 × SD of differences.

CVR assessments by ASL and SPECT in the ROI study. A, CVR values measured by ASL are plotted against the corresponding CVR values measured by SPECT from bilateral frontal and temporal ROIs. The broken line shows the line of equality. B, Bland-Altman plot of CVR values measured by ASL and SPECT. The broken line shows average of differences, and the solid line indicates ±1.96× SD of differences.

A, ROC curves of CBF by ASL for detection of CBF reduction on SPECT. Area under the curve is 0.98. B, ROC curves of CVR by ASL for detection of CVR reduction on SPECT. Area under the curve is 0.99. TPF, true-positive fraction; FPF, false-positive fraction.