Article Figures & Data
Figures
- Fig 1.
The first case is a 69-year-old male patient with right stroke who underwent CTA that showed a large IPH component of 107 mm3 (A–C). A, The coronal view of the carotid CTA is given with the segmentation of the software (white open arrow). B, A coronal cut of the postprocessed carotid arteries is shown (white arrowhead). C, The white arrow indicates the internal carotid artery in the axial selected section. The legend of the chromatic scale is the following: red = IPH; yellow = lipid-IPH component; blue = mixed component; green = calcified component. The second case is a 73-year-old male patient with left MCA stroke with an IPH/lipid ratio of 0.93 (D–F). D–F, Three axial slices from the bifurcation upward were selected showing the presence of a large IPH and the small amount of lipid-IPH (white arrowheads).
- Fig 2.
Boxplot of the volume components of the carotid artery plaque according to the presence or absence of cerebral symptoms (A) and boxplot of the percentages of the components according to the presence or absence of cerebrovascular symptoms (B).
- Fig 3.
ROC curve analysis of the volume components of the carotid artery plaque according to the presence or absence of cerebral symptoms (A) and ROC curve analysis of the percentages of the components according to the presence or absence of cerebral symptoms (B).
Tables
Cerebrovascular Symptoms Yes No P Value Test Demographics Age (mean) (95% CI) (yr) 70 (66–74) 68 (65–71) .37 Paired Student t Sex (male = 93) 80% (37/46) 74% (57/77) .55 χ2 Hypertension 26% (12/46) 27% (42/154) .98 χ2 CAD 50% (23/46) 45% (70/154) .71 χ2 Smoking status 43% (20/46) 30% (46/154) .12 χ2 Diabetes 7% (3/43) 7% (11/154) .85 χ2 Dyslipidemia 28% (13/46) 32% (49/154) .79 χ2 Plaque composition Total plaque volume (mm3) 793 (565–984) 560 (503–669) .105 Mann-Whitney Lipid volume (mm3) 187 (132–240) 79 (63–101) .002a Mann-Whitney Mixed volume (mm3) 471 (400–544) 318 (290–367) .062 Mann-Whitney Calcified volume (mm3) 103 (70–150) 128 (109–156) .16 Mann-Whitney IPH volume (mm3) 115 (74–160) 2 (0–9) .001a Mann-Whitney Lipid-IPH volume (mm3) 61 (37–110) 67 (60–87) .14 Mann-Whitney % of lipid 23 (21–30) 17 (14–18) .002a Mann-Whitney % of mixed 58 (56–63) 59 (56–61) .51 Mann-Whitney % of calcium 13 (12–17) 21 (18–22) .001a Mann-Whitney % of IPH 15 (12–18) 1 (0–3) .001a Mann-Whitney % of lipid-IPH 8 (6–11) 13 (12–14) .001a Mann-Whitney IPH/lipid ratio 0.69 (0.59–0.73) 0.019 (0–0.064) .001a Mann-Whitney Note:—CAD indicates coronary artery disease.
↵a Significant.
AUC SE 95% CI P Value Plaque volume 0.579 0.049 0.507–0.648 .108 IPH volume 0.793 0.0421 0.730–0.847 .001 Lipid minus IPH 0.574 0.0486 0.502–0.643 .129 Lipid volume 0.648 0.0486 0.577–0.714 .002 Mixed volume 0.594 0.0465 0.523–0.663 .043 Calcium volume 0.568 0.0517 0.497–0.638 .186 % of lipid 0.679 0.0476 0.609–0.743 .001 % of mixed 0.532 0.0459 0.460–0.602 .489 % of calcium 0.591 0.0426 0.522–0.654 .135 % of IPH 0.812 0.0413 0.751–0.863 .001 % of lipid minus IPH 0.702 0.0428 0.633–0.764 .001 IPH/lipid radio 0.811 0.0424 0.751–0.863 .001 Note:—SE indicates standard error.
χ2 Contingency Coefficient P Value IPH, 10 mm3 12.527 0.243 .001 IPH, 50 mm3 43.913 0.424 .001 IPH, 100 mm3 37.478 0.397 .001 IPH, 150 mm3 34.763 0.385 .001 IPH, 200 mm3 14.935 0.264 .001 IPH, 250 mm3 7.944 0.195 .048
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