Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Other Publications
    • ajnr

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

Welcome to the new AJNR, Updated Hall of Fame, and more. Read the full announcements.


AJNR is seeking candidates for the position of Associate Section Editor, AJNR Case Collection. Read the full announcement.

 

Research ArticlePediatrics
Open Access

Characterization of MR Imaging–Visible Perivascular Spaces in the White Matter of Healthy Adolescents at 3T

J. Piantino, E.L. Boespflug, D.L. Schwartz, M. Luther, A.M. Morales, A. Lin, R.V. Fossen, L. Silbert and B.J. Nagel
American Journal of Neuroradiology November 2020, 41 (11) 2139-2145; DOI: https://doi.org/10.3174/ajnr.A6789
J. Piantino
aFrom the Department of Pediatrics (J.P., M.L.), Division of Child Neurology, Doernbecher Children’s Hospital
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for J. Piantino
E.L. Boespflug
bDepartment of Neurology (E.L.B., D.L.S., L.S.), Layton Aging and Alzheimer’s Disease Center
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for E.L. Boespflug
D.L. Schwartz
bDepartment of Neurology (E.L.B., D.L.S., L.S.), Layton Aging and Alzheimer’s Disease Center
cAdvanced Imaging Research Center (D.L.S.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for D.L. Schwartz
M. Luther
aFrom the Department of Pediatrics (J.P., M.L.), Division of Child Neurology, Doernbecher Children’s Hospital
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for M. Luther
A.M. Morales
dDepartment of Psychiatry (A.M.M., R.V.F., B.J.N.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for A.M. Morales
A. Lin
eDepartment of Emergency Medicine (A.L.), Center for Policy and Research in Emergency Medicine
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for A. Lin
R.V. Fossen
dDepartment of Psychiatry (A.M.M., R.V.F., B.J.N.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for R.V. Fossen
L. Silbert
bDepartment of Neurology (E.L.B., D.L.S., L.S.), Layton Aging and Alzheimer’s Disease Center
fDepartment of Neurology (L.S.), Portland Veterans Affairs Medical Center, Portland, Oregon
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for L. Silbert
B.J. Nagel
dDepartment of Psychiatry (A.M.M., R.V.F., B.J.N.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for B.J. Nagel
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

Article Information

vol. 41 no. 11 2139-2145
DOI 
https://doi.org/10.3174/ajnr.A6789
PubMed 
33033050

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received May 19, 2020
  • Accepted after revision July 17, 2020
  • Published online November 11, 2020.

Copyright & Usage 
© 2020 by American Journal of Neuroradiology Indicates open access to non-subscribers at www.ajnr.org

Author Information

  1. J. Piantinoa,
  2. E.L. Boespflugb,
  3. D.L. Schwartzb,c,
  4. M. Luthera,
  5. A.M. Moralesd,
  6. A. Line,
  7. R.V. Fossend,
  8. L. Silbertb,f and
  9. B.J. Nageld
  1. aFrom the Department of Pediatrics (J.P., M.L.), Division of Child Neurology, Doernbecher Children’s Hospital
  2. bDepartment of Neurology (E.L.B., D.L.S., L.S.), Layton Aging and Alzheimer’s Disease Center
  3. cAdvanced Imaging Research Center (D.L.S.)
  4. dDepartment of Psychiatry (A.M.M., R.V.F., B.J.N.)
  5. eDepartment of Emergency Medicine (A.L.), Center for Policy and Research in Emergency Medicine
  6. fDepartment of Neurology (L.S.), Portland Veterans Affairs Medical Center, Portland, Oregon
  1. Please address correspondence to Juan A. Piantino, MD, 707 SW Gaines St., Portland, OR 97239; e-mail: piantino{at}ohsu.edu
View Full Text

Funding

  • National Institute on Aging

    K01AG059842; P30 AG008017
  • National Heart, Lung, and Blood Institute

    K12HL133115; K23HL150217-01
  • National Institute on Drug Abuse

    K01DA046649

Altmetrics

Cited By...

  • 39 Citations
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Neuroimaging standards for research into small vessel disease—advances since 2013
    Marco Duering, Geert Jan Biessels, Amy Brodtmann, Christopher Chen, Charlotte Cordonnier, Frank-Erik de Leeuw, Stéphanie Debette, Richard Frayne, Eric Jouvent, Natalia S Rost, Annemieke ter Telgte, Rustam Al-Shahi Salman, Walter H Backes, Hee-Joon Bae, Rosalind Brown, Hugues Chabriat, Alberto De Luca, Charles deCarli, Anna Dewenter, Fergus N Doubal, Michael Ewers, Thalia S Field, Aravind Ganesh, Steven Greenberg, Karl G Helmer, Saima Hilal, Angela C C Jochems, Hanna Jokinen, Hugo Kuijf, Bonnie Y K Lam, Jessica Lebenberg, Bradley J MacIntosh, Pauline Maillard, Vincent C T Mok, Leonardo Pantoni, Salvatore Rudilosso, Claudia L Satizabal, Markus D Schirmer, Reinhold Schmidt, Colin Smith, Julie Staals, Michael J Thrippleton, Susanne J van Veluw, Prashanthi Vemuri, Yilong Wang, David Werring, Marialuisa Zedde, Rufus O Akinyemi, Oscar H Del Brutto, Hugh S Markus, Yi-Cheng Zhu, Eric E Smith, Martin Dichgans, Joanna M Wardlaw
    The Lancet Neurology 2023 22 7
  • Imaging perivascular space structure and function using brain MRI
    Giuseppe Barisano, Kirsten M. Lynch, Francesca Sibilia, Haoyu Lan, Nien-Chu Shih, Farshid Sepehrband, Jeiran Choupan
    NeuroImage 2022 257
  • Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease
    Marie-Gabrielle Duperron, Maria J. Knol, Quentin Le Grand, Tavia E. Evans, Aniket Mishra, Ami Tsuchida, Gennady Roshchupkin, Takahiro Konuma, David-Alexandre Trégouët, Jose Rafael Romero, Stefan Frenzel, Michelle Luciano, Edith Hofer, Mathieu Bourgey, Nicole D. Dueker, Pilar Delgado, Saima Hilal, Rick M. Tankard, Florian Dubost, Jean Shin, Yasaman Saba, Nicola J. Armstrong, Constance Bordes, Mark E. Bastin, Alexa Beiser, Henry Brodaty, Robin Bülow, Caty Carrera, Christopher Chen, Ching-Yu Cheng, Ian J. Deary, Piyush G. Gampawar, Jayandra J. Himali, Jiyang Jiang, Takahisa Kawaguchi, Shuo Li, Melissa Macalli, Pascale Marquis, Zoe Morris, Susana Muñoz Maniega, Susumu Miyamoto, Masakazu Okawa, Matthew Paradise, Pedram Parva, Tatjana Rundek, Muralidharan Sargurupremraj, Sabrina Schilling, Kazuya Setoh, Omar Soukarieh, Yasuharu Tabara, Alexander Teumer, Anbupalam Thalamuthu, Julian N. Trollor, Maria C. Valdés Hernández, Meike W. Vernooij, Uwe Völker, Katharina Wittfeld, Tien Yin Wong, Margaret J. Wright, Junyi Zhang, Wanting Zhao, Yi-Cheng Zhu, Helena Schmidt, Perminder S. Sachdev, Wei Wen, Kazumichi Yoshida, Anne Joutel, Claudia L. Satizabal, Ralph L. Sacco, Guillaume Bourque, Quentin Le Grand, Mark Lathrop, Tomas Paus, Israel Fernandez-Cadenas, Qiong Yang, Bernard Mazoyer, Philippe Boutinaud, Yukinori Okada, Hans J. Grabe, Karen A. Mather, Reinhold Schmidt, Marc Joliot, M. Arfan Ikram, Fumihiko Matsuda, Christophe Tzourio, Joanna M. Wardlaw, Sudha Seshadri, Hieab H. H. Adams, Stéphanie Debette
    Nature Medicine 2023 29 4
  • Longitudinal MRI-visible perivascular space (PVS) changes with long-duration spaceflight
    Kathleen E. Hupfeld, Sutton B. Richmond, Heather R. McGregor, Daniel L. Schwartz, Madison N. Luther, Nichole E. Beltran, Igor S. Kofman, Yiri E. De Dios, Roy F. Riascos, Scott J. Wood, Jacob J. Bloomberg, Ajitkumar P. Mulavara, Lisa C. Silbert, Jeffrey J. Iliff, Rachael D. Seidler, Juan Piantino
    Scientific Reports 2022 12 1
  • Brain perivascular space imaging across the human lifespan
    Kirsten M. Lynch, Farshid Sepehrband, Arthur W. Toga, Jeiran Choupan
    NeuroImage 2023 271
  • The Bidirectional Link Between Sleep Disturbances and Traumatic Brain Injury Symptoms: A Role for Glymphatic Dysfunction?
    Juan A. Piantino, Jeffrey J. Iliff, Miranda M. Lim
    Biological Psychiatry 2022 91 5
  • A critical guide to the automated quantification of perivascular spaces in magnetic resonance imaging
    William Pham, Miranda Lynch, Gershon Spitz, Terence O’Brien, Lucy Vivash, Benjamin Sinclair, Meng Law
    Frontiers in Neuroscience 2022 16
  • MRI-visible Dilated Perivascular Space in the Brain by Age: The Human Connectome Project
    Hyun Gi Kim, Na-Young Shin, Yoonho Nam, Eunkyeong Yun, Uicheul Yoon, Hye Sun Lee, Kook Jin Ahn
    Radiology 2023 306 3
  • The etiology and evolution of magnetic resonance imaging-visible perivascular spaces: Systematic review and meta-analysis
    Serhat V. Okar, Fengling Hu, Russell T. Shinohara, Erin S. Beck, Daniel S. Reich, Benjamin V. Ineichen
    Frontiers in Neuroscience 2023 17
  • Aging, prevalence and risk factors of MRI-visible enlarged perivascular spaces
    Frances Rodriguez Lara, Ashlea Lynn Scruton, Adlin Pinheiro, Serkalem Demissie, Pedram Parva, Andreas Charidimou, Michael Francis, Jayandra J. Himali, Charles DeCarli, Alexa Beiser, Sudha Seshadri, Jose R. Romero
    Aging 2022 14 17
  • MRI-visible Perivascular Spaces in the Neonatal Brain
    Jee Young Kim, Yoonho Nam, Sumin Kim, Na-Young Shin, Hyun Gi Kim
    Radiology 2023 307 2
  • The perivascular space is a conduit for cerebrospinal fluid flow in humans: A proof-of-principle report
    Erin A. Yamamoto, Jacob H. Bagley, Mathew Geltzeiler, Olabisi R. Sanusi, Aclan Dogan, Jesse J. Liu, Juan Piantino
    Proceedings of the National Academy of Sciences 2024 121 42
  • Perivascular spaces as a marker of disease severity and neurodegeneration in patients with behavioral variant frontotemporal dementia
    Jasmine Moses, Benjamin Sinclair, Daniel L. Schwartz, Lisa C. Silbert, Terence J. O’Brien, Meng Law, Lucy Vivash
    Frontiers in Neuroscience 2022 16
  • Macroscopic changes in aquaporin-4 underlie blast traumatic brain injury-related impairment in glymphatic function
    Molly Braun, Mathew Sevao, Samantha A Keil, Elizabeth Gino, Marie X Wang, Janet Lee, Mariya A Haveliwala, Emily Klein, Sanjana Agarwal, Taylor Pedersen, C Harker Rhodes, Deidre Jansson, David Cook, Elaine Peskind, Daniel P Perl, Juan Piantino, Abigail G Schindler, Jeffrey J Iliff
    Brain 2024 147 6
  • MRI-Visible Perivascular Spaces Associated With Cognitive Impairment in Military Veterans With Traumatic Brain Injury Mediated by CSF P-Tau
    Ming-Liang Wang, Dian-Xu Yang, Zheng Sun, Wen-Bin Li, Qiao-Qiao Zou, Peng-Yang Li, Xue Wu, Yue-Hua Li
    Frontiers in Psychiatry 2022 13
  • Systematic review and meta-analysis of automated methods for quantifying enlarged perivascular spaces in the brain
    Jennifer M.J. Waymont, Maria del C. Valdés Hernández, José Bernal, Roberto Duarte Coello, Rosalind Brown, Francesca M. Chappell, Lucia Ballerini, Joanna M. Wardlaw
    NeuroImage 2024 297
  • Characteristics of perivascular space dilatation in normal aging
    Chang‐hyun Park, Na‐Young Shin, Yoonho Nam, Uicheul Yoon, Kookjin Ahn, Seung‐Koo Lee
    Human Brain Mapping 2023 44 8
  • Correlation between enlarged perivascular space and brain white matter hyperintensities in patients with recent small subcortical infarct
    Xiuli Jian, Fubiao Xu, Mi Yang, Min Zhang, Wenwei Yun
    Brain and Behavior 2023 13 9
  • Overview of the Current Knowledge and Conventional MRI Characteristics of Peri- and Para-Vascular Spaces
    Marco Parillo, Federica Vaccarino, Gianfranco Di Gennaro, Sumeet Kumar, Johan Van Goethem, Bruno Beomonte Zobel, Carlo Cosimo Quattrocchi, Paul M. Parizel, Carlo Augusto Mallio
    Brain Sciences 2024 14 2
  • Enlarged perivascular spaces are associated with white matter injury, cognition and inflammation in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
    Nikolaos Karvelas, Bradley Oh, Earnest Wang, Yann Cobigo, Torie Tsuei, Stephen Fitzsimons, Kyan Younes, Alexander Ehrenberg, Michael D Geschwind, Daniel Schwartz, Joel H Kramer, Adam R Ferguson, Bruce L Miller, Lisa C Silbert, Howard J Rosen, Fanny M Elahi
    Brain Communications 2024 6 2
  • An Enlarged Perivascular Space: Clinical Relevance and the Role of Imaging in Aging and Neurologic Disorders
    Younghee Yim, Won-Jin Moon
    Journal of the Korean Society of Radiology 2022 83 3
  • Perivascular Space Burden and Cerebrospinal Fluid Biomarkers in US Veterans With Blast-Related Mild Traumatic Brain Injury
    Erin A. Yamamoto, Seiji Koike, Madison Luther, Laura Dennis, Miranda M. Lim, Murray Raskind, Kathleen Pagulayan, Jeffrey Iliff, Elaine Peskind, Juan A. Piantino
    Journal of Neurotrauma 2024 41 13-14
  • Automatic Quantification of Enlarged Perivascular Space in Patients With Traumatic Brain Injury Using Super-Resolution of T2-Weighted Images
    Jiachen Zhuo, Prashant Raghavan, Muhan Shao, Steven Roys, Xiao Liang, Rosy Linda Njonkou Tchoquessi, Chandler Sours Rhodes, Neeraj Badjatia, Jerry L. Prince, Rao P. Gullapalli
    Journal of Neurotrauma 2024 41 3-4
  • Beyond the AJR: Updates on the Glymphatic System, Perivascular Spaces, and Autism During Infancy
    Sarah J. Moum, Judith A. Gadde
    American Journal of Roentgenology 2024 223 6
  • Enlarged brain perivascular spaces correlate with blood plasma osmolality in the healthy population: A longitudinal study
    Alexandra Morozova, Filip Španiel, Antonín Škoch, Marek Brabec, Grygoriy Zolotarov, Vladimir Musil, Petr Zach
    NeuroImage 2024 300
  • Machine Learning–Based Perivascular Space Volumetry in Alzheimer Disease
    Katerina Deike, Andreas Decker, Paul Scheyhing, Julia Harten, Nadine Zimmermann, Daniel Paech, Oliver Peters, Silka D. Freiesleben, Luisa-Sophie Schneider, Lukas Preis, Josef Priller, Eike Spruth, Slawek Altenstein, Andrea Lohse, Klaus Fliessbach, Okka Kimmich, Jens Wiltfang, Claudia Bartels, Niels Hansen, Frank Jessen, Ayda Rostamzadeh, Emrah Düzel, Wenzel Glanz, Enise I. Incesoy, Michaela Butryn, Katharina Buerger, Daniel Janowitz, Michael Ewers, Robert Perneczky, Boris-Stephan Rauchmann, Stefan Teipel, Ingo Kilimann, Doreen Goerss, Christoph Laske, Matthias H. Munk, Annika Spottke, Nina Roy, Michael Wagner, Sandra Roeske, Michael T. Heneka, Frederic Brosseron, Alfredo Ramirez, Laura Dobisch, Steffen Wolfsgruber, Luca Kleineidam, Renat Yakupov, Melina Stark, Matthias C. Schmid, Moritz Berger, Stefan Hetzer, Peter Dechent, Klaus Scheffler, Gabor C. Petzold, Anja Schneider, Alexander Effland, Alexander Radbruch
    Investigative Radiology 2024 59 9
  • Neuroimaging in headache: possible findings and their interpretation
    O.V. Serousova, M.I. Karpova, N.B. Nadtochiy, D.G. Korotkova, A.F. Vasilenko
    Russian Journal of Pain 2022 20 3
  • Perivascular spaces visible on magnetic resonance imaging predict subsequent delirium in older patients
    Quhong Song, Yanli Zhao, Taiping Lin, Jirong Yue
    Frontiers in Aging Neuroscience 2022 14
  • Beyond the cerebellum: perivascular space burden in spinocerebellar ataxia type 3 extends to multiple brain regions
    Yonghua Huang, Zhiming Zhen, Lihua Deng, Peiling Ou, Linfeng Shi, Feng Shi, Rui Hua, Jiaojiao Wu, Wei Chen, Ru Wen, Jian Wang, Chen Liu
    Brain Communications 2025 7 2
  • Changes of brain parenchyma free water fraction reflect tissue damage and impaired processing speed in multiple sclerosis
    Alessandra Stella Caporale, Antonio Maria Chiarelli, Emma Biondetti, Alessandro Villani, Ilona Lipp, Davide Di Censo, Valentina Tomassini, Richard Geoffrey Wise
    Human Brain Mapping 2024 45 9
  • Dynamic changes in perivascular space morphology predict signs of spaceflight-associated neuro-ocular syndrome in bed rest
    Sutton B. Richmond, Rachael D. Seidler, Jeffrey J. Iliff, Daniel L. Schwartz, Madison Luther, Lisa C. Silbert, Scott J. Wood, Jacob J. Bloomberg, Edwin Mulder, Jessica K. Lee, Alberto De Luca, Juan Piantino
    npj Microgravity 2024 10 1
  • Enlarged perivascular space in the temporal lobe as a prognostic marker in temporal lobe epilepsy with hippocampal sclerosis
    Soomi Cho, Seungwon Song, Jungyon Yum, Eun Hwa Kim, Yun Ho Roh, Won‐Joo Kim, Kyoung Heo, Han Kyu Na, Kyung Min Kim
    Epilepsia 2025
  • MR Imaging of Neurofluids in the Developing Brain
    Nivedita Agarwal, Willemijn Klein, Ruth O’Gorman Tuura
    Neuroimaging Clinics of North America 2025 35 2
  • Neuraxial Therapeutics
    Deidre J. Jansson, Jeffrey J. Iliff
    2023
  • Perivascular space imaging during therapy for medulloblastoma
    Ruitian Song, John O. Glass, Shengjie Wu, Yimei Li, Giles W. Robinson, Amar Gajjar, Thomas E. Merchant, Wilburn E. Reddick, Arka Bhowmik
    PLOS ONE 2025 20 2
  • Quantifying dilated perivascular spaces in children with sickle cell disease
    Kristine A. Karkoska, Jahnavi Gollamudi, Russell P. Sawyer, Daniel Woo, Hyacinth I. Hyacinth
    Pediatric Blood & Cancer 2024 71 9
  • Repetitive Head Impacts and Perivascular Space Volume in Former American Football Players
    Leonard B. Jung, Tim L. T. Wiegand, Fatima Tuz-Zahra, Yorghos Tripodis, Jeffrey J. Iliff, Juan Piantino, Hector Arciniega, Cara L. Kim, Lara Pankatz, Sylvain Bouix, Alexander P. Lin, Michael L. Alosco, Daniel H. Daneshvar, Jesse Mez, Farshid Sepehrband, Yogesh Rathi, Ofer Pasternak, Michael J. Coleman, Charles H. Adler, Charles Bernick, Laura Balcer, Jeffrey L. Cummings, Eric M. Reiman, Robert A. Stern, Martha E. Shenton, Inga K. Koerte, Yi Su, Kewei Chen, Hillary Protas, Conni Boker, Rhoda Au, Robert C. Cantu, Lindsay Farrer, Robert Helm, Neil Kowall, Gustavo Mercier, James Otis, Jason Weller, Irene Simkin, Alondra Andino, Shannon Conneely, Courtney Diamond, Tessa Fagle, Olivia Haller, Tennyson Hung, Nicole Gullotti, Megan Mariani, Brian Mayville, Kathleen McLaughlin, Mary Nanna, Taylor Platt, Sury Pulukuri, Fiona Rica, Madison Sestak, Michael McClean, Douglas Annis, Christine Chaisson, Dianne B. Dixon, Carolyn Finney, Kerrin Gallagher, Kaitlin Hartlage, Jun Lu, Brett Martin, Emmanuel Ojo, Joseph N. Palmisano, Brittany Pine, Janani Ramachandran, Jennifer Fitzsimmons, Elena M. Bonke, Katherine Breedlove, Eduardo Coello, Hujiun Liao, Elizabeth Rizzoni, Vivian Schultz, Annelise Silva, Brynn Vessey, Sarah Banks, Jason Miller, Aaron Ritter, marwan Sabbagh, Raelynn de la Cruz, Jan Durant, Moragn Golceker, Nicolette Harmon, Kaeson Kaylegian, Rachelle Long, Christin Nance, Priscilla Sandoval, Robert W. Turner, Kenneth L. Marek, Andrew Serrano, David W. Dodick, Yonas Geda, Jennifer V. Wethe, Bryce Falk, Amy Duffy, Marci Howard, Michelle Montague, Thomas Osgood, Debra Babcock, William Barr, Judith Goldberg, Thomas Wisniewski, Ivian Kirov, Yvonne Lui, Charles Marmar, Lisene Hasanaj, Liliana Serrano, Alhassan Al-Kharafi, Allan George, Sammie Martin, Edward Riley, William Runge, Elaine R. Peskind, Elizabeth Colasurdo, Daniel S. Marcus, Jenny Gurney, Keith A. Johnson, Richard Greenwald
    JAMA Network Open 2024 7 8
  • Robust, fully-automated assessment of cerebral perivascular spaces and white matter lesions: a multicentre MRI longitudinal study of their evolution and association with risk of dementia and accelerated brain atrophy
    Giuseppe Barisano, Michael Iv, Jeiran Choupan, Melanie Hayden-Gephart, Michael Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John Morris, Leslie M. Shaw, Enchi Liu, Tom Montine, Ronald G. Thomas, Michael Donohue, Sarah Walter, Devon Gessert, Tamie Sather, Gus Jiminez, Danielle Harvey, Michael Donohue, Matthew Bernstein, Nick Fox, Paul Thompson, Norbert Schuff, Charles DeCarli, Bret Borowski, Jeff Gunter, Matt Senjem, Prashanthi Vemuri, David Jones, Kejal Kantarci, Chad Ward, Robert A. Koeppe, Norm Foster, Eric M. Reiman, Kewei Chen, Chet Mathis, Susan Landau, Nigel J. Cairns, Erin Householder, Lisa Taylor Reinwald, Virginia Lee, Magdalena Korecka, Michal Figurski, Karen Crawford, Scott Neu, Tatiana M. Foroud, Steven Potkin, Li Shen, Faber Kelley, Sungeun Kim, Kwangsik Nho, Zaven Kachaturian, Richard Frank, Peter J. Snyder, Susan Molchan, Jeffrey Kaye, Joseph Quinn, Betty Lind, Raina Carter, Sara Dolen, Lon S. Schneider, Sonia Pawluczyk, Mauricio Beccera, Liberty Teodoro, Bryan M. Spann, James Brewer, Helen Vanderswag, Adam Fleisher, Judith L. Heidebrink, Joanne L. Lord, Ronald Petersen, Sara S. Mason, Colleen S. Albers, David Knopman, Kris Johnson, Rachelle S. Doody, Javier Villanueva Meyer, Munir Chowdhury, Susan Rountree, Mimi Dang, Yaakov Stern, Lawrence S. Honig, Karen L. Bell, Beau Ances, John C. Morris, Maria Carroll, Sue Leon, Erin Householder, Mark A. Mintun, Stacy Schneider, Angela Oliver, Daniel Marson, Randall Griffith, David Clark, David Geld-macher, John Brockington, Erik Roberson, Hillel Grossman, Effie Mitsis, Leyla deToledo-Morrell, Raj C. Shah, Ranjan Duara, Daniel Varon, Maria T. Greig, Peggy Roberts, Marilyn Albert, Chiadi Onyike, Daniel D’Agostino, Stephanie Kielb, James E. Galvin, Dana M. Pogorelec, Brittany Cerbone, Christina A. Michel, Henry Rusinek, Mony J. de Leon, Lidia Glodzik, Susan De Santi, P. Murali Doraiswamy, Jeffrey R. Petrella, Terence Z. Wong, Steven E. Arnold, Jason H. Karlawish, David Wolk, Charles D. Smith, Greg Jicha, Peter Hardy, Partha Sinha, Elizabeth Oates, Gary Conrad, Oscar L. Lopez, MaryAnn Oakley, Donna M. Simpson, Anton P. Porsteinsson, Bonnie S. Goldstein, Kim Martin, Kelly M. Makino, M. Saleem Ismail, Connie Brand, Ruth A. Mulnard, Gaby Thai, Catherine Mc Adams Ortiz, Kyle Womack, Dana Mathews, Mary Quiceno, Ramon Diaz Arrastia, Richard King, Myron Weiner, Kristen Martin Cook, Michael DeVous, Allan I. Levey, James J. Lah, Janet S. Cellar, Jeffrey M. Burns, Heather S. Anderson, Russell H. Swerdlow, Liana Apostolova, Kathleen Tingus, Ellen Woo, Daniel H.S. Silverman, Po H. Lu, George Bartzokis, Neill R. Graff Radford, Francine Parfitt, Tracy Kendall, Heather Johnson, Martin R. Farlow, AnnMarie Hake, Brandy R. Matthews, Scott Herring, Cynthia Hunt, Christopher H. van Dyck, Richard E. Carson, Martha G. MacAvoy, Howard Chertkow, Howard Bergman, Chris Hosein, Sandra Black, Bojana Stefanovic, Curtis Caldwell, Ging-Yuek Robin Hsiung, Howard Feldman, Benita Mudge, Michele Assaly, Andrew Kertesz, John Rogers, Dick Trost, Charles Bernick, Donna Munic, Diana Kerwin, Marek Marsel Mesulam, Kristine Lipowski, Chuang Kuo Wu, Nancy Johnson, Carl Sadowsky, Walter Martinez, Teresa Villena, Raymond Scott Turner, Kathleen Johnson, Brigid Reynolds, Reisa A. Sperling, Keith A. Johnson, Gad Marshall, Meghan Frey, Jerome Yesavage, Joy L. Taylor, Barton Lane, Allyson Rosen, Jared Tinklenberg, Marwan N. Sabbagh, Christine M. Belden, Sandra A. Jacobson, Sherye A. Sirrel, Neil Kowall, Ronald Killiany, Andrew E. Budson, Alexander Norbash, Patricia Lynn Johnson, Thomas O. Obisesan, Saba Wolday, Joanne Allard, Alan Lerner, Paula Ogrocki, Leon Hudson, Evan Fletcher, Owen Carmichael, John Olichney, Charles DeCarli, Smita Kittur, Michael Borrie, T.Y. Lee, Rob Bartha, Sterling Johnson, Sanjay Asthana, Cynthia M. Carlsson, Steven G. Potkin, Adrian Preda, Dana Nguyen, Pierre Tariot, Adam Fleisher, Stephanie Reeder, Vernice Bates, Horacio Capote, Michelle Rainka, Douglas W. Scharre, Maria Kataki, Anahita Adeli, Earl A. Zimmerman, Dzintra Celmins, Alice D. Brown, Godfrey D. Pearlson, Karen Blank, Karen Anderson, Robert B. Santulli, Tamar J. Kitzmiller, Eben S. Schwartz, Kaycee M. Sink, Jeff D. Williamson, Pradeep Garg, Franklin Watkins, Brian R. Ott, Henry Querfurth, Geoffrey Tremont, Stephen Salloway, Paul Malloy, Stephen Correia, Howard J. Rosen, Bruce L. Miller, Jacobo Mintzer, Kenneth Spicer, David Bachman, Elizabeth Finger, Stephen Pasternak, Irina Rachinsky, John Rogers, Andrew Kertesz, Dick Drost, Nunzio Pomara, Raymundo Hernando, Antero Sarrael, Susan K. Schultz, Laura L. Boles Ponto, Hyungsub Shim, Karen Elizabeth Smith, Norman Relkin, Gloria Chaing, Lisa Raudin, Amanda Smith, Kristin Fargher, Balebail Ashok Raj
    eBioMedicine 2025 111
  • Visualization of perivascular spaces in the human brain with 5-T magnetic resonance imaging
    Sirui Liu, Jianbo Li, Rui Hua, Yaowen Xing, Jiaojiao Wu, Jiang Lin, Jian Wang, Yan Shan, Lei Xu, Feng Shi, Mengsu Zeng
    BMC Neuroscience 2025 26 1
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 41 (11)
American Journal of Neuroradiology
Vol. 41, Issue 11
1 Nov 2020
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Characterization of MR Imaging–Visible Perivascular Spaces in the White Matter of Healthy Adolescents at 3T
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
J. Piantino, E.L. Boespflug, D.L. Schwartz, M. Luther, A.M. Morales, A. Lin, R.V. Fossen, L. Silbert, B.J. Nagel
Characterization of MR Imaging–Visible Perivascular Spaces in the White Matter of Healthy Adolescents at 3T
American Journal of Neuroradiology Nov 2020, 41 (11) 2139-2145; DOI: 10.3174/ajnr.A6789

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Characterization of MR Imaging–Visible Perivascular Spaces in the White Matter of Healthy Adolescents at 3T
J. Piantino, E.L. Boespflug, D.L. Schwartz, M. Luther, A.M. Morales, A. Lin, R.V. Fossen, L. Silbert, B.J. Nagel
American Journal of Neuroradiology Nov 2020, 41 (11) 2139-2145; DOI: 10.3174/ajnr.A6789
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • MATERIALS AND METHODS
    • RESULTS
    • DISCUSSION
    • CONCLUSIONS
    • Footnotes
    • References
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • PubMed
  • Google Scholar

Cited By...

  • Association of hypoxic-ischemic injury with MRI-derived glymphatic function markers in neonates: analysis of perivascular space volume and diffusion-tensor imaging
  • Biological sex and BMI influence the longitudinal evolution of adolescent and young adult MRI-visible perivascular spaces
  • A Systematic Review and Meta-Analysis of Automated Methods for Quantifying Enlarged Perivascular Spaces in the Brain
  • Enlarged Perivascular Spaces are Associated with White Matter Injury, Brain Atrophy, Cognitive Decline and Markers of Inflammation in an Autosomal Dominant Vascular Neurodegenerative Disease (CADASIL)
  • Brain perivascular space imaging across the human lifespan
  • Crossref (39)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Neuroimaging standards for research into small vessel disease—advances since 2013
    Marco Duering, Geert Jan Biessels, Amy Brodtmann, Christopher Chen, Charlotte Cordonnier, Frank-Erik de Leeuw, Stéphanie Debette, Richard Frayne, Eric Jouvent, Natalia S Rost, Annemieke ter Telgte, Rustam Al-Shahi Salman, Walter H Backes, Hee-Joon Bae, Rosalind Brown, Hugues Chabriat, Alberto De Luca, Charles deCarli, Anna Dewenter, Fergus N Doubal, Michael Ewers, Thalia S Field, Aravind Ganesh, Steven Greenberg, Karl G Helmer, Saima Hilal, Angela C C Jochems, Hanna Jokinen, Hugo Kuijf, Bonnie Y K Lam, Jessica Lebenberg, Bradley J MacIntosh, Pauline Maillard, Vincent C T Mok, Leonardo Pantoni, Salvatore Rudilosso, Claudia L Satizabal, Markus D Schirmer, Reinhold Schmidt, Colin Smith, Julie Staals, Michael J Thrippleton, Susanne J van Veluw, Prashanthi Vemuri, Yilong Wang, David Werring, Marialuisa Zedde, Rufus O Akinyemi, Oscar H Del Brutto, Hugh S Markus, Yi-Cheng Zhu, Eric E Smith, Martin Dichgans, Joanna M Wardlaw
    The Lancet Neurology 2023 22 7
  • Imaging perivascular space structure and function using brain MRI
    Giuseppe Barisano, Kirsten M. Lynch, Francesca Sibilia, Haoyu Lan, Nien-Chu Shih, Farshid Sepehrband, Jeiran Choupan
    NeuroImage 2022 257
  • Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease
    Marie-Gabrielle Duperron, Maria J. Knol, Quentin Le Grand, Tavia E. Evans, Aniket Mishra, Ami Tsuchida, Gennady Roshchupkin, Takahiro Konuma, David-Alexandre Trégouët, Jose Rafael Romero, Stefan Frenzel, Michelle Luciano, Edith Hofer, Mathieu Bourgey, Nicole D. Dueker, Pilar Delgado, Saima Hilal, Rick M. Tankard, Florian Dubost, Jean Shin, Yasaman Saba, Nicola J. Armstrong, Constance Bordes, Mark E. Bastin, Alexa Beiser, Henry Brodaty, Robin Bülow, Caty Carrera, Christopher Chen, Ching-Yu Cheng, Ian J. Deary, Piyush G. Gampawar, Jayandra J. Himali, Jiyang Jiang, Takahisa Kawaguchi, Shuo Li, Melissa Macalli, Pascale Marquis, Zoe Morris, Susana Muñoz Maniega, Susumu Miyamoto, Masakazu Okawa, Matthew Paradise, Pedram Parva, Tatjana Rundek, Muralidharan Sargurupremraj, Sabrina Schilling, Kazuya Setoh, Omar Soukarieh, Yasuharu Tabara, Alexander Teumer, Anbupalam Thalamuthu, Julian N. Trollor, Maria C. Valdés Hernández, Meike W. Vernooij, Uwe Völker, Katharina Wittfeld, Tien Yin Wong, Margaret J. Wright, Junyi Zhang, Wanting Zhao, Yi-Cheng Zhu, Helena Schmidt, Perminder S. Sachdev, Wei Wen, Kazumichi Yoshida, Anne Joutel, Claudia L. Satizabal, Ralph L. Sacco, Guillaume Bourque, Quentin Le Grand, Mark Lathrop, Tomas Paus, Israel Fernandez-Cadenas, Qiong Yang, Bernard Mazoyer, Philippe Boutinaud, Yukinori Okada, Hans J. Grabe, Karen A. Mather, Reinhold Schmidt, Marc Joliot, M. Arfan Ikram, Fumihiko Matsuda, Christophe Tzourio, Joanna M. Wardlaw, Sudha Seshadri, Hieab H. H. Adams, Stéphanie Debette
    Nature Medicine 2023 29 4
  • Longitudinal MRI-visible perivascular space (PVS) changes with long-duration spaceflight
    Kathleen E. Hupfeld, Sutton B. Richmond, Heather R. McGregor, Daniel L. Schwartz, Madison N. Luther, Nichole E. Beltran, Igor S. Kofman, Yiri E. De Dios, Roy F. Riascos, Scott J. Wood, Jacob J. Bloomberg, Ajitkumar P. Mulavara, Lisa C. Silbert, Jeffrey J. Iliff, Rachael D. Seidler, Juan Piantino
    Scientific Reports 2022 12 1
  • Brain perivascular space imaging across the human lifespan
    Kirsten M. Lynch, Farshid Sepehrband, Arthur W. Toga, Jeiran Choupan
    NeuroImage 2023 271
  • The Bidirectional Link Between Sleep Disturbances and Traumatic Brain Injury Symptoms: A Role for Glymphatic Dysfunction?
    Juan A. Piantino, Jeffrey J. Iliff, Miranda M. Lim
    Biological Psychiatry 2022 91 5
  • A critical guide to the automated quantification of perivascular spaces in magnetic resonance imaging
    William Pham, Miranda Lynch, Gershon Spitz, Terence O’Brien, Lucy Vivash, Benjamin Sinclair, Meng Law
    Frontiers in Neuroscience 2022 16
  • MRI-visible Dilated Perivascular Space in the Brain by Age: The Human Connectome Project
    Hyun Gi Kim, Na-Young Shin, Yoonho Nam, Eunkyeong Yun, Uicheul Yoon, Hye Sun Lee, Kook Jin Ahn
    Radiology 2023 306 3
  • The etiology and evolution of magnetic resonance imaging-visible perivascular spaces: Systematic review and meta-analysis
    Serhat V. Okar, Fengling Hu, Russell T. Shinohara, Erin S. Beck, Daniel S. Reich, Benjamin V. Ineichen
    Frontiers in Neuroscience 2023 17
  • Aging, prevalence and risk factors of MRI-visible enlarged perivascular spaces
    Frances Rodriguez Lara, Ashlea Lynn Scruton, Adlin Pinheiro, Serkalem Demissie, Pedram Parva, Andreas Charidimou, Michael Francis, Jayandra J. Himali, Charles DeCarli, Alexa Beiser, Sudha Seshadri, Jose R. Romero
    Aging 2022 14 17

More in this TOC Section

  • Comparison of Image Quality and Radiation Dose in Pediatric Temporal Bone CT Using Photon-Counting Detector CT and Energy-Integrating Detector CT
  • SyMRI & MR Fingerprinting in Brainstem Myelination
  • Venous Sinus Stenosis in Mucopolysaccharidosis I
Show more Pediatrics

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editors Choice
  • Fellow Journal Club
  • Letters to the Editor

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

Special Collections

  • Special Collections

Resources

  • News and Updates
  • Turn around Times
  • Submit a Manuscript
  • Author Policies
  • Manuscript Submission Guidelines
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Submit a Case
  • Become a Reviewer/Academy of Reviewers
  • Get Peer Review Credit from Publons

Multimedia

  • AJNR Podcast
  • AJNR SCANtastic
  • Video Articles

About Us

  • About AJNR
  • Editorial Board
  • Not an AJNR Subscriber? Join Now
  • Alerts
  • Feedback
  • Advertise with us
  • Librarian Resources
  • Permissions
  • Terms and Conditions

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire