MR Imaging of Pediatric Low-Grade Gliomas: Pretherapeutic Differentiation of BRAF V600E Mutation, BRAF Fusion, and Wild-Type Tumors in Patients without Neurofibromatosis-1

A. Trasolini; C. Erker; S. Cheng; C. Crowell; K. McFadden; R. Moineddin; M.A. Sargent; D. Mata-Mbemba

doi:10.3174/ajnr.A7574

Research ArticlePediatrics

MR Imaging of Pediatric Low-Grade Gliomas: Pretherapeutic Differentiation of BRAF V600E Mutation, BRAF Fusion, and Wild-Type Tumors in Patients without Neurofibromatosis-1

A. Trasolini, C. Erker, S. Cheng, C. Crowell, K. McFadden, R. Moineddin, M.A. Sargent and D. Mata-Mbemba

American Journal of Neuroradiology August 2022, 43 (8) 1196-1201; DOI: https://doi.org/10.3174/ajnr.A7574

A. Trasolini

aFrom the IWK Health Centre (A.T., C.E., C.C., K.M., D.M.-M.), Halifax, Nova Scotia, Canada

bDalhousie University Medical School (A.T.), Halifax, Nova Scotia, Canada

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for A. Trasolini

C. Erker

aFrom the IWK Health Centre (A.T., C.E., C.C., K.M., D.M.-M.), Halifax, Nova Scotia, Canada

cDepartments of Pediatrics (C.E.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for C. Erker

S. Cheng

gDivision of Hematology, Oncology, and Bone Marrow Transplant (S.C.), Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for S. Cheng

C. Crowell

aFrom the IWK Health Centre (A.T., C.E., C.C., K.M., D.M.-M.), Halifax, Nova Scotia, Canada

fFaculty of Science (C.C.), Dalhousie University, Halifax, Nova Scotia, Canada

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for C. Crowell

K. McFadden

aFrom the IWK Health Centre (A.T., C.E., C.C., K.M., D.M.-M.), Halifax, Nova Scotia, Canada

dPathology (K.M.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for K. McFadden

R. Moineddin

hUniversity of Toronto Dalla Lana School of Public Health (R.M.), Toronto, Ontario, Canada

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for R. Moineddin

M.A. Sargent

iDepartment of Radiology (M.A.S.), British Columbia Children’s Hospital and University of British Columbia, Vancouver, British Columbia, Canada

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for M.A. Sargent

D. Mata-Mbemba

aFrom the IWK Health Centre (A.T., C.E., C.C., K.M., D.M.-M.), Halifax, Nova Scotia, Canada

eDiagnostic Radiology (D.M.-M.)

jDepartment of Diagnostic Imaging (D.M.-M.), IWK Health Centre, Halifax, Nova Scotia, Canada

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for D. Mata-Mbemba

Article
Figures & Data
Supplemental
Info & Metrics
Responses
References
PDF

Submit a Response to This Article

Compose eLetter

Title *

Contents

More information about text formats

Plain text

No HTML tags allowed.
Web page addresses and e-mail addresses turn into links automatically.
Lines and paragraphs break automatically.

Author Information

Contributors
First Name and Middle Initial * First or given name, e.g. 'Peter'. Last Name * Your last, or family, name, e.g. 'MacMoody'. Email Address * Your email address, e.g. higgs-boson@gmail.com Occupation * Your role and/or occupation, e.g. 'Orthopedic Surgeon'. Affiliation * Your organization or institution (if applicable), e.g. 'Royal Free Hospital'.

Statement of Competing Interests

Competing interests? *

Yes

Please describe the competing interests

Vertical Tabs

Jump to comment:

No eLetters have been published for this article.

PreviousNext

In this issue

American Journal of Neuroradiology

Vol. 43, Issue 8

1 Aug 2022

Table of Contents
Index by author
Complete Issue (PDF)

Download PDF

Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following MR Imaging of Pediatric Low-Grade Gliomas: Pretherapeutic Differentiation of BRAF V600E Mutation, BRAF Fusion, and Wild-Type Tumors in Patients without Neurofibromatosis-1

Message Subject (Your Name) has sent you a message from American Journal of Neuroradiology

Message Body (Your Name) thought you would like to see the American Journal of Neuroradiology web site.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Cite this article

A. Trasolini, C. Erker, S. Cheng, C. Crowell, K. McFadden, R. Moineddin, M.A. Sargent, D. Mata-Mbemba

MR Imaging of Pediatric Low-Grade Gliomas: Pretherapeutic Differentiation of BRAF V600E Mutation, BRAF Fusion, and Wild-Type Tumors in Patients without Neurofibromatosis-1

American Journal of Neuroradiology Aug 2022, 43 (8) 1196-1201; DOI: 10.3174/ajnr.A7574

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

0 Responses

Respond to this article

Bookmark this article

User Name *

Password *

Remember my user name & password.

MRI of PEDS Low-Grade Gliomas and BRAF

A. Trasolini, C. Erker, S. Cheng, C. Crowell, K. McFadden, R. Moineddin, M.A. Sargent, D. Mata-Mbemba

American Journal of Neuroradiology Aug 2022, 43 (8) 1196-1201; DOI: 10.3174/ajnr.A7574

Share This Article:

Tweet Widget
Facebook Like
Google Plus One

Purchase

Jump to section

Article
Figures & Data
Supplemental
Info & Metrics
Responses
References
PDF

PubMed
Google Scholar

Cited By...

CNS Embryonal Tumor with PLAGL Amplification, a New Tumor in Children and Adolescents: Insights from a Comprehensive MRI Analysis
Multiparametric MRI Along with Machine Learning Informs on Molecular Underpinnings, Prognosis, and Treatment Response in Pediatric Low-Grade Glioma
Imaging Clusters of Pediatric Low-Grade Glioma are Associated with Distinct Molecular Characteristics
Identification of Multiclass Pediatric Low-Grade Neuroepithelial Tumor Molecular Subtype with ADC MR Imaging and Machine Learning

Crossref (6)
Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

CNS Embryonal Tumor with PLAGL Amplification, a New Tumor in Children and Adolescents: Insights from a Comprehensive MRI Analysis

A. Tietze, B. Bison, J. Engelhardt, T. Fenouil, D. Figarella-Branger, E. Goebell, J. Hakumäki, E. Koscielniak, L.E. Ludlow, D. Meyronet, P. Nyman, I. Øra, J. Pesola, T. Rauramaa, R.E. Reddingius, D. Samuel, A. Sexton-Oates, A. Vasiljevic, A.K. Wefers, J. Zamecnik, D.T.W. Jones, M.K. Keck, K. von Hoff

American Journal of Neuroradiology 2025 46 3
Identification of Multiclass Pediatric Low-Grade Neuroepithelial Tumor Molecular Subtype with ADC MR Imaging and Machine Learning

Matheus D. Soldatelli, Khashayar Namdar, Uri Tabori, Cynthia Hawkins, Kristen Yeom, Farzad Khalvati, Birgit B. Ertl-Wagner, Matthias W. Wagner

American Journal of Neuroradiology 2024 45 6
MRI characteristics predict BRAF V600E status in gangliogliomas and pleomorphic xanthoastrocytomas and provide survival prognostication

Bingqing Jiang, Yingyan Zheng, Dejun She, Zhen Xing, Dairong Cao

Acta Radiologica 2024 65 1
Multiparametric MRI along with machine learning predicts prognosis and treatment response in pediatric low-grade glioma

Anahita Fathi Kazerooni, Adam Kraya, Komal S. Rathi, Meen Chul Kim, Arastoo Vossough, Nastaran Khalili, Ariana M. Familiar, Deep Gandhi, Neda Khalili, Varun Kesherwani, Debanjan Haldar, Hannah Anderson, Run Jin, Aria Mahtabfar, Sina Bagheri, Yiran Guo, Qi Li, Xiaoyan Huang, Yuankun Zhu, Alex Sickler, Matthew R. Lueder, Saksham Phul, Mateusz Koptyra, Phillip B. Storm, Jeffrey B. Ware, Yuanquan Song, Christos Davatzikos, Jessica B. Foster, Sabine Mueller, Michael J. Fisher, Adam C. Resnick, Ali Nabavizadeh

Nature Communications 2025 16 1
Multimodal contrastive learning for enhanced explainability in pediatric brain tumor molecular diagnosis

Sara Ketabi, Matthias W. Wagner, Cynthia Hawkins, Uri Tabori, Birgit Betina Ertl-Wagner, Farzad Khalvati

Scientific Reports 2025 15 1
Performance of Machine Learning Models in Predicting BRAF Alterations Using Imaging Data in Low-Grade Glioma: A Systematic Review and Meta-Analysis

Shahryar Rajai Firouzabadi, Roozbeh Tavanaei, Ida Mohammadi, Alireza Alikhani, Ali Ansari, Mohammadhosein Akhlaghpasand, Bardia Hajikarimloo, Raymund L. Yong, Konstantinos Margetis

World Neurosurgery 2025 195

Main menu

User menu

Search

American Journal of Neuroradiology

MR Imaging of Pediatric Low-Grade Gliomas: Pretherapeutic Differentiation of BRAF V600E Mutation, BRAF Fusion, and Wild-Type Tumors in Patients without Neurofibromatosis-1

Plain text

Vertical Tabs

Jump to comment:

In this issue

Citation Manager Formats

Related Articles

Cited By...

More in this TOC Section

Similar Articles

Indexed Content

Cases

Special Collections

Resources

Multimedia

About Us

American Society of Neuroradiology