Case of the Week
Section Editors: Matylda Machnowska1 and Anvita Pauranik2
1University of Toronto, Toronto, Ontario, Canada
2BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada
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January 14, 2008
Neurosyphilis
- Caused by Treponema Pallidum; Southeast region has highest U.S. incidence.
- CNS involvement occurs during the secondary stage (meningitis) or tertiary stage (acute meningitis, meningovascular and parenchymal disease).
- May result in infarctions of medium-to-small size arteries Luetic labyrinthitis:
- enhancement of VII/VIII cranial nerves and labyrinth, spread to cochlea via endo- or perilymph or hematogeneous dissemination
- Osteitis with 'moth-eaten' demineralization of otic capsule